Results 81 to 90 of about 14,164 (239)

Anti-inflammaging and antiglycation activity of a novel botanical ingredient from African biodiversity (Centevita™)

, 2013
Giada Maramaldi,1 Stefano Togni,1 Federico Franceschi,1 Elian Lati21Indena SpA, Milan, Italy; 2Laboratoire BIO-EC, Longjumeau, FrancePurpose: The aim of this study was to investigate the topical efficacy of a new purified extract from Madagascar, Gotu ...
Lati E, Franceschi F, Maramaldi G, Togni S   +3 more
core  

Comments to the “Letter to the Editor” for the manuscript titled “Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease”

Brain Pathology, EarlyView.
Beta amyloid diffuse plaques, neurofibrillary tangles and neuritic plaques, are increased in densities at the intermediate stage of Alzheimer's neuropathological change. These pathological changes releasing Pathogen‐Associated Molecular Patterns (PAMPs) and Damage‐Associated Molecular Patterns (DAMPs).
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source

Alpha synuclein and inflammaging

Heliyon
The α-synuclein protein is an established molecule in Lewy body pathology, especially Parkinson's disease (PD). While the pathological role of α-synuclein (α-syn) in PD has been well described, novel evidence may suggest that α-syn interacts with inflammasomes in response to aging.
Geneviève L. Putnam, Robert W. Maitta
openaire   +3 more sources

A comprehensive review of cancer‐induced cardiac wasting

British Journal of Pharmacology, EarlyView.
Cancer is frequently accompanied by cachexia, a systemic syndrome characterized by progressive loss of skeletal muscle mass, with or without loss of fat mass. Increasing evidence indicates that cancer can also induce cardiac muscle wasting, which is associated with structural cardiac remodelling, impaired contractile function and the development of ...
Alessia Lena, Muhammad Shahzeb Khan, Ulrich Keller, Lars Bullinger, Dominik P. Modest, Markus S. Anker   +5 more
wiley   +1 more source

Baicalin alleviates uterine inflammaging and improves eggshell quality in aged laying hens

Frontiers in Immunology
Aging is a major contributor to the decline in egg quality, with uterine inflammaging playing a key role in this process. Implementing anti-aging strategies to prevent uterine inflammaging and sustain optimal eggshell quality is imperative.
Dan Shao, Yuan Qu, Liang Qu, Haibing Tong   +3 more
doaj   +1 more source

Epigenetic Mechanisms Involved in Inflammaging-Associated Hypertension

, 2022
Purpose of Review: This review summarizes the involvement of inflammaging in vascular damage with focus on the epigenetic mechanisms by which inflammaging-induced hypertension is triggered.
Ferder, León, Manucha, Walter, Chuffa, Luiz Gustavo A. [UNESP], Simão, Vinícius Augusto [UNESP]   +3 more
core   +1 more source

Mechanisms underlying the protective effects of San‐Bai decoction against UV radiation on the skin

International Journal of Cosmetic Science, EarlyView.
Combining conventional differential expression analysis with differential network analysis offers a promising strategy to uncover the mechanistic basis of the holistic benefits provided by herbal blends. Our findings demonstrated that San‐Bai decoction modulates multiple pathways—not only those related to skin pigmentation, such as ET‐1 signalling, but
Rui Zhang, Hong Zhang, Chengming Zhang, Wencai Jiang, Luonan Chen, Yimei Tan, Ying Zou, Xuelan Gu   +7 more
wiley   +1 more source

The Role of the Inflammasome in Inflammaging [PDF]

There is an increase in inflammation during aging, leading to a chronic state of low-level inflammation known as inflammaging. The inflammasome, a multiprotein complex of the innate immune response, contributes to inflammaging.
Cyr, Brianna
core   +3 more sources

Senescent cell-derived extracellular vesicles as potential mediators of innate immunosenescence and inflammaging

Experimental Gerontology
Ageing is accompanied by a decline in immune function (immunosenescence), increased inflammation (inflammaging), and more senescent cells which together contribute to age-related disease and infection susceptibility. The innate immune system is the front-
Shaun Hanley, Yung-Yi Chen, Jon Hazeldine, Janet M. Lord   +3 more
doaj   +1 more source

The Causal Effect of Supra‐ and Sub‐Gingival Instrumentation on the Oral Microbiome of Elderly Periodontitis Patients Treated in Nursing Homes: Secondary Analysis of a Randomised Controlled Trial

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aims Periodontitis among nursing home residents is increasing as more older adults retain their dentition. Evidence on the impact of periodontal therapy on their oral microbiota is limited. We aimed to assess the effect of outreach‐based supra‐ and sub‐gingival instrumentation on the periodontal microbiome.
Anna Greta Barbe, Daniel Hagenfeld, Carolin Walther, Dalia Beck, Fedja Farowski, Maria J. G. T. Vehreschild, Sonja H. M. Derman, Sven Kleine Bardenhorst, Dirk Bleiel   +8 more
wiley   +1 more source