Results 161 to 170 of about 15,244 (279)

Development and Validation of a Nomogram to Predict Respiratory Failure With Influenza

Immunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Purpose Influenza‐induced respiratory failure is a severe complication of influenza that can rapidly progress to multi‐organ failure or even death due to severe impairment of pulmonary ventilation or gas exchange function. Early prediction and intervention can decrease the mortality in patients with respiratory failure. Methods A comprehensive
Mingzhen Zhao, Yi Li, Hongxiang Fu, Guanghui Jia, Xing Zhao, Yu Sun, Xingbin Li, Hongbo Zhang, Zhiwei Zhao   +8 more
wiley   +1 more source

Controversies Surrounding Critical‐Size Defects: Influence of Age and Biological Characteristics

Journal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 6, June 2026.
ABSTRACT Critical‐size defects (CSDs) in craniofacial reconstruction refer to osseous gaps that fail to heal spontaneously, increasing the risk of neurological impairment and craniofacial dysmorphology. Despite decades of investigation, controversy still exists surrounding the definition of CSDs, with criteria varying across species, experimental ...
Andrew Nordlund, Hana Shah, Nicholas A. Mirsky, Kashyap K. Tadisina, Arturo J. Rios‐Diaz, Vasudev Vivekanand Nayak, Estevam A. Bonfante, Paulo G. Coelho   +7 more
wiley   +1 more source

Editorial: Unraveling inflammaging: a pathway to prevent age-related disease in animals, volume II. [PDF]

Front Vet Sci
Arai T.
europepmc   +1 more source

Inflammaging: Immune-Metabolic Crosstalk Between the Prostate-Testis and Musculoskeletal System. [PDF]

Int J Mol Sci
Bossio S, Russa D, Rago V, Di Dio M, Aversa A, Perri A.   +5 more
europepmc   +1 more source

Gut Microbiota as a Key Modulator in the Pathophysiology of Sepsis: SURVEIL Project

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
Longitudinal profiling of 132 hospitalized patients reveals that age, colonization status, and sepsis interact to shape gut microbiota diversity and composition. Sepsis is associated with reduced alpha diversity, beta‐diversity shifts, functional predictions (methanogenesis, nitrate/sulfate respiration), and partial MDR overlap with bloodstream ...
Chiara Bazzano, Alice Caramaschi, Nadia Massa, Silvio Collani, Marta Mellai, Nadia Barizzone, Andrea Rocchetti, Paolo Bottino, Maria Simona Caroppo, Valeria Bonato, Rosanna Vaschetto, Sara Scaglione, Alessia Francese, Narges Gholami, Claudio Caria, Paola Bianchi, Cristiano Lauritano, Luigi Castello, Annalisa Roveta, Antonio Maconi, Stefano Andreoni, Sandra Dalfonso, Elisa Bona   +22 more
wiley   +1 more source

Targeting Mitochondria in Aging‐Related Diseases: Therapeutic Potential and Obstacles

MedComm, Volume 7, Issue 6, June 2026.
This article systematically summarized the specific mechanism of aging‐related diseases caused by mitochondrial dysfunction, and summarized the broad‐spectrum treatment methods and disease targeted treatment strategies for mitochondria. At the same time, it also pointed out the dilemma faced by mitochondrial targeted treatment.
Zijie Xiang, Yu Chen, Xishui Liu, Haowen Lu, Yuqing Yang, Lei Xing, Yu Zhang, Chuandong Lang, Siming Zhang, Shixiang Zhao, Youzhi Hong, Jiaxiang Bai, Yusen Qiao   +12 more
wiley   +1 more source

Author Correction: NRF1-mediated innate immune response drives inflammaging. [PDF]

Nat Commun
Lei H, Zhao T, Zhang J, Long Y, Chen Y, Zhu Y, Meng Y, Tang Y, Liu X, Sun J, Li Z, Su J, Gong F, Chen G, Sun B, Chen Y, Chen Q, Li Y, Zhu Y.   +18 more
europepmc   +1 more source

Spermidine Mitigates Immune Cell Senescence and Boosts Vaccine Responses in Healthy Older Adults—A Pilot Study

Aging Cell, Volume 25, Issue 6, June 2026.
Can we boost vaccine responses in older adults? In a double‐blind, randomised, placebo‐controlled pilot study (n = 40, > 65 years), spermidine supplementation (6 mg/day, 13 weeks) was safe and significantly improved immune responses following a 3rd SARS‐CoV‐2 vaccine dose.
Ghada Alsaleh, Mohammad Ali, Amir Hossein Kayvanjoo, Feng Liu, Tanaïs Moreau, Sagida Bibi, Lin Luo, Melissa Govender, Miles Carroll, Sebastian J. Hofer, Eisenberg Tobias, Christoph Magnes, Loren Kell, Christopher Chung, Yu Deng, Aneesha Bhandari, Lucy Garner, Thomas Conrad, Liye Chen, Barbara Kronsteiner‐Dobramysl, Susie Dunachie, Owen B. Spiller, Teresa Lambe, Paul Klenerman, Lucy C. Jones, A. Katharina Simon   +25 more
wiley   +1 more source

Bridging aging and colorectal cancer: synergistic roles of inflammaging and immunosenescence. [PDF]

Front Immunol
Zaongo SD, Yang Q, Han M, Xi T, Luo Z, Wang X, Yang J, Ouyang J.   +7 more
europepmc   +1 more source

Sex‐Specific Regulation of the Turandot Gene Family Modulates Temperature‐Dependent Lifespan in Drosophila melanogaster

Aging Cell, Volume 25, Issue 6, June 2026.
Multi‐omics analysis in Drosophila reveals that temperature‐driven lifespan changes are actively regulated, not purely thermodynamic. The Turandot gene family mediates this response, and its knockdown extends lifespan across temperatures with sex‐specific effects, establishing tot genes as key genetic regulators of thermal longevity.
Jessica M. Hoffman, A. Tate Lasher, Michael P. Fitch, Steven N. Austad, Liou Y. Sun   +4 more
wiley   +1 more source