Results 141 to 150 of about 18,204 (247)

Anemia in the frail, elderly patient

Clinical Interventions in Aging, 2016
Gabriele Röhrig1,2 1Ageing Clinical Research, Department II of Internal Medicine, University Hospital Cologne, 2Department of Geriatrics, St Marien Hospital Cologne, Cologne, Germany Abstract: Anemia and frailty are two common findings in ...
Röhrig G
doaj  

Anthraquinones and Aloe Vera Extracts as Potential Modulators of Inflammaging Mechanisms: A Translational Approach from Autoimmune to Onco-Hematological Diseases

Molecules
Inflammaging is a chronic, low-grade inflammatory state that contributes to age-related diseases, including cardiovascular disorders, osteoporosis, neurodegeneration, and cancer. This process involves immunosenescence, oxidative stress, and immune aging,
Raffaele Cordiano, Santino Caserta, Paola Lucia Minciullo, Alessandro Allegra, Sebastiano Gangemi   +4 more
doaj   +1 more source

Growth differentiation factor 15 mitigates lipotoxic steatosis by preserving mitochondrial morphodynamics and augmenting fatty acid oxidation in hepatocytes and liver organoids

Diabetes, Obesity and Metabolism, Volume 28, Issue 5, Page 3788-3806, May 2026.
Abstract Aims Growth differentiation factor 15 (GDF15) has emerged as a promising metabolic regulator with hepatoprotective properties in metabolic dysfunction‐associated steatotic liver disease (MASLD), yet its underlying mechanisms remain elusive.
Jia Li, Qi Zhou, Mengmeng Xia, Yakun Li, Junyu Wang, Manon Buist‐Homan, Vincent E. de Meijer, Hans Blokzijl, Klaas Nico Faber, Han Moshage   +9 more
wiley   +1 more source

Lifelong Exercise as a Modulator of CD4+ T Cell Immunometabolism

European Journal of Clinical Investigation, Volume 56, Issue 5, May 2026.
Hypothetical framework illustrating how physical exercise initiated early in life acts as a critical immunomodulatory factor by promoting optimal immune function from childhood and establishing a better “immunometabolic functional peak”. This early advantage may confer sustained benefits to CD4+ T cell metabolism and immune competence across aging ...
Bruna Spolador de Alencar Silva, Amanda Veiga Sardeli, Ricardo R. Agostinete, Helena Batatinha, Alessandra Peres, José César Rosa‐Neto, José Teixeira, Manuel J. Coelho‐e‐Silva, Paulo J. Oliveira, Fábio Santos Lira   +9 more
wiley   +1 more source

Reversing inflammaging [PDF]

Nature Reviews Drug Discovery, 2020
openaire   +1 more source

T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age‐Related Diseases

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Cardiovascular diseases (CVD) are shaped by a complex interplay with immune mechanisms. In particular, the distinct roles of antigen‐specific T cell mechanisms are emerging as critical determinants across a broad spectrum of conditions, ranging from atherosclerosis, myocardial infarction (MI), heart failure (HF), and myocarditis. Because these
Leon Richter, João Dias‐Ferreira, Gustavo Campos Ramos, DiyaaElDin Ashour   +3 more
wiley   +1 more source

Pathophysiology and Molecular Signalling in Osteoporosis: Linking Risk Factors to Bone Loss

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Osteoporosis is a prevalent skeletal disorder characterised by progressive reduction in bone mass, microarchitectural deterioration, and increased fracture susceptibility. In India, approximately one‐third of the elderly population is affected by bone‐related disorders, and the global burden of osteoporosis continues to rise.
Pramoda G., Kamini Shivhare, Piyush Kumar Gupta, Amirhossein Sahebkar, Prashant Kesharwani, Rahul Shukla   +5 more
wiley   +1 more source

Study on the Multiple Efficacies of Vitamin C Serum in Anti‐Glycation, Anti‐Carbonylation, Antioxidation, and Anti‐Inflammation of Human Skin Based on In Vivo Tests

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Skin glycation, oxidation, carbonylation, and excessive inflammation are well‐recognized factors contributing to skin aging and pigmentation. Previous in vitro studies have confirmed vitamin C's antioxidant, anti‐glycation, and anti‐inflammatory properties, but its in vivo effects remain to be further verified.
Yusha Zi, Jianwei Liu, Qi Liu, Yao Pan, Xiuyu Jiang   +4 more
wiley   +1 more source

Changes of erythropoiesis in case of chronic obstructive pulmonary disease and urolithiasis comorbidity [PDF]

, 2016
In comorbidity of chronic obstructive pulmonary disease and urolithiasis with oxalic acid stones changes of erythropoiesis were found in 78,3 % of patients, in particular – 52,2 % corresponded to mild iron-deficiency anemia and in 26,1 % of patients ...
Khukhlina, O.S., Viligorska, K.V.
core  

Translating inflammaging: The bidirectional relationship between oral and systemic health in geriatric prosthodontics

Archives of Gerontology and Geriatrics Plus
The aging population presents complex challenges to oral health, particularly due to inflammaging, a chronic, low-grade systemic inflammation linked to tissue degeneration and frailty syndrome. Despite its relevance, inflammaging remains underexplored in
Olga Naka, Panagiota Chatzidou, Katia Sarafidou, Vassiliki Anastassiadou   +3 more
doaj   +1 more source