Results 151 to 160 of about 14,164 (239)

Understanding and addressing resistance to IMiDs immunomodulatory compounds in multiple myeloma

The FEBS Journal, Volume 293, Issue 17, Page 5121-5139, September 2026.
IMiDs are pivotal in the treatment of multiple myeloma. Mechanisms of resistance comprise cell intrinsic and extrinsic pathways, involving tumour microenvironment, immune cell dysfunction, CRBN‐dependent and independent genetic drivers and epigenetic changes.
Maria‐Cynthia Fuentes‐Lacouture, Devi Nandana, Karthik Ramasamy, Anjan Thakurta   +3 more
wiley   +1 more source

Hypothalamic Inflammaging: A Central Driver of Type 2 Diabetes Mellitus and Metabolic Disease in Aging. [PDF]

Diabetes Metab J
Lyoo SH, Kim KH, Kim KW.
europepmc   +1 more source

Complement Activation by Post‐Translationally Modified Proteins: Links to Chronic Inflammation and Autoimmunity

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT Post‐translational modifications (PTMs) of proteins are essential to maintain homeostasis as many cellular processes rely on reversible PTMs. However, several PTMs, particularly irreversible PTMs in the extracellular space, can contribute to tissue dysfunction, inflammation, and may even trigger the development of autoimmunity against PTM ...
Marleen M. J. van Greevenbroek, Leendert A. Trouw   +1 more
wiley   +1 more source

Predicting susceptibility to inflammaging using a genetic inflammatory index through Prakriti-based phenotypic stratification. [PDF]

Front Immunol
Bera N, Gowri S A, Syed N, Govinda V, Rao AK, Jeeru J, Kurthkoti K, Narayanaswamy K, Jakka SR, Raghawan AK, Nair P, Oruganti B.   +11 more
europepmc   +1 more source

Anti‐Aging Potential of Callus Culture: Mechanisms, Efficacy and Future Trends

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Callus culture technology revolutionizes skin antiaging research, offering a sustainable and efficient method for producing bioactive compounds with potent geroprotective properties. This plant tissue and cell culture technique enables the controlled biosynthesis of beneficial phytochemicals while mitigating the variability and ...
Amir Mohammad Sharafi, Ali Khajeei, Maryam Hasan Zadeh Navroodi, Soheila Mokari, Seydeh Halimeh Najafi, Mohaddeseh Argha, Faezeh Talaei Shahmirzadi, Parina Asgharian, Tooba Gholikhani   +8 more
wiley   +1 more source

Biomarkers of Inflammaging and Cellular Senescence in Musculoskeletal (MSK) Diseases: The Knowns and the Unknowns. [PDF]

Biomedicines
Ganguly P.
europepmc   +1 more source

The immunology behind inflammaging-causes, sources, and mechanisms. [PDF]

J Allergy Clin Immunol
Sturmlechner I, LeBrasseur NK, Weyand CM, Goronzy JJ.   +3 more
europepmc   +1 more source

Effects of a Dietary Supplement on Systemic Aging Related Biomarkers and Skin Aging Outcomes in Middle‐Aged Women: In Vitro and Clinical Studies

Journal of Cosmetic Dermatology, Volume 25, Issue 9, September 2026.
ABSTRACT Background Interest in dietary supplements targeting both skin and biological aging biomarkers is rapidly growing, yet existing studies lack rigorous clinical validation of combined oral–topical regimens and concurrent assessment of skin and systemic biomarkers.
Jie‐Hua Chen, Liugang Ding, Pingping Lv, Wenzhi Li, Meiling Tai, Ran Yin, Yi Yu, Yunru Huang, Jinluan Zheng, Erman Wang, Huan Liu, Jiaojiao Fu, Hongjue Wang, Ruopan Huang, Jun Ma   +14 more
wiley   +1 more source

Inflammaging and immunosenescence-driven remodeling of the immune microenvironment in osteoarthritis: mechanisms, immune regulation and immune reprogramming. [PDF]

Front Immunol
Wang T, Jiang W, Chen X, Fu S, Hu K, Zeng L.   +5 more
europepmc   +1 more source

Natural Agents for Preventing Skin Damage Induced by Visible Light: A Systematic Review of Preclinical and Clinical Evidence

Photodermatology, Photoimmunology &Photomedicine, Volume 42, Issue 5, September 2026.
ABSTRACT Background/Purpose Visible light (VL), and particularly high‐energy visible light (HEVL), reaching Earth's surface has emerged as a relevant contributor to skin damage. VL has been implicated in oxidative stress, inflammation, pigmentation disorders, and photoaging, especially in individuals with darker skin phototypes.
Azahara Rodríguez‐Luna, Alicia Zamarrón, Cristina García‐Muñoz, Juan‐Carlos Hernández‐Rodríguez, Henry W. Lim, Salvador González   +5 more
wiley   +1 more source