Results 151 to 160 of about 18,204 (247)

Alpha synuclein and inflammaging

Heliyon
The α-synuclein protein is an established molecule in Lewy body pathology, especially Parkinson's disease (PD). While the pathological role of α-synuclein (α-syn) in PD has been well described, novel evidence may suggest that α-syn interacts with inflammasomes in response to aging.
Geneviève L. Putnam, Robert W. Maitta
openaire   +2 more sources

DNA-PK-mediated phosphorylation of STAT6 establishes a non-canonical type 2 immunity axis to prevent macrophage senescence

Nature Communications
Macrophage senescence drives inflammaging, a chronic, age-related inflammation. To date, the protective mechanisms against inflammaging are poorly defined.
Zhao Zhou, Xinmeng Li, Yushuang Wang, Long Liang, Chunyang Wang, Yongchang Sun, Dongmei Wu, Yifu Qiu   +7 more
doaj   +1 more source

MAM‐STAT3‐Driven Mitochondrial Ca+2 Upregulation Contributes to Immunosenescence in Type A Mandibuloacral Dysplasia Patients

Advanced Science
Individuals with homozygous laminA/C p.R527C mutations manifest a severe form of Mandibuloacral dysplasia‐(MAD) and exhibit overlapping progeroid symptoms, for which the underlying molecular pathology remains unknown.
Arshad Ahmed Padhiar, Xiaohong Yang, Syed Aqib Ali Zaidi, Zhu Li, Jinqi Liao, Wei Shu, Arif Ali Chishti, Liangge He, Gulzar Alam, Abdullah Faqeer, Ilyas Ali, Shuai Zhang, Ting Wang, Tao Liu, Meiling Zhou, Gang Wang, Yan Zhou, Guangqian Zhou   +17 more
doaj   +1 more source

Osteoimmunologic and Immune-Aging Signatures in Postmenopausal Women with Periodontitis and Low Bone Mineral Density: A Cross-Sectional Study. [PDF]

Diagnostics (Basel)
Sufaru IG, Martu MA, Laza MG, Solomon SM, Luchian I, Pasarin L, Tatarciuc D, Martu I.   +7 more
europepmc   +1 more source

Rosemary Aqueous Extract as a Natural Alternative to Retinol for Skin Aging Intervention. [PDF]

Pharmaceuticals (Basel)
Gao P, Zhang H, Gu X.
europepmc   +1 more source

Diet and Exercise Interventions in Pediatric Cancer Survivors and Effects on Cardiometabolic Disease Risk and Inflammaging Biomarkers: A Systematic Review. [PDF]

Adv Nutr
Cares K, Bryner A, DiPiazza B, Chakos K, Schmidt ML, Gabel K.   +5 more
europepmc   +1 more source

An inflammation-defying adjuvant "micro"manages age-diminished vaccine efficacy. [PDF]

Mol Ther Nucleic Acids
Liu G.
europepmc   +1 more source

Exploring the nexus between inflammation and mobility through the lens of healthy aging: current scenario and future perspectives. [PDF]

Aging Clin Exp Res
Patusco R, Gyasi K, Kaufmann A.
europepmc   +1 more source

Age is the work of art? : impact of neutrophil and organism age on neutrophil extracellular trap formation [PDF]

, 2017
Elzbieta Kolaczkowska, Weronika Ortmann
core   +1 more source

Inflammaging and Cardiovascular Risk in Old Women. [PDF]

High Blood Press Cardiovasc Prev
Moscucci F, Baratta F, Bucciarelli V, Mattioli AV, Pinti M, Zanini G, Sciomer S, Gallina S, Piccirillo G, Desideri G.   +9 more
europepmc   +1 more source