Results 211 to 220 of about 18,204 (247)
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Bladder cancer, inflammageing and microbiomes
Nature Reviews Urology, 2022Ageing is correlated with elevated bladder cancer incidence, morbidity and mortality. Advanced age is also associated with elevated markers of chronic inflammation and perturbations in gut and urinary tract microbiota. One reason for the increased incidence and mortality of bladder cancer in the elderly might be that age-associated changes in multiple ...
Martin, Austin +4 more
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Ammonia-Induced Glial-Inflammaging
Molecular Neurobiology, 2020Astrocytes are functionally diverse glial cells that maintain blood-brain barrier (BBB) integrity, provide metabolic and trophic support, and react to pathogens or harmful stimuli through inflammatory response. Impairment of astrocyte functions has been implicated in hepatic encephalopathy (HE), a neurological complication associated with ...
Larissa Daniele Bobermin +3 more
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Inflammaging and Anti-Inflammaging: The Role of Cytokines in Extreme Longevity
Archivum Immunologiae Et Therapiae Experimentalis, 2015Longevity and aging are two sides of the same coin, as they both derive from the interaction between genetic and environmental factors. Aging is a complex, dynamic biological process characterized by continuous remodeling. One of the most recent theories on aging focuses on immune response, and takes into consideration the activation of subclinical ...
Paola Lucia Minciullo +2 more
exaly +5 more sources
2019
Inflammaging refers to the chronic, low-grade inflammation that develops with age and may favor the onset of age-related diseases (ARDs) and geriatric syndromes (GSs). Many molecular mechanisms are involved in causing inflammaging, from innate immunity activation to increased availability of DAMPs and to mitochondria-ER stress. Inflammaging is emerging
Capri M., Franceschi C., Salvioli S.
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Inflammaging refers to the chronic, low-grade inflammation that develops with age and may favor the onset of age-related diseases (ARDs) and geriatric syndromes (GSs). Many molecular mechanisms are involved in causing inflammaging, from innate immunity activation to increased availability of DAMPs and to mitochondria-ER stress. Inflammaging is emerging
Capri M., Franceschi C., Salvioli S.
openaire +1 more source
Nihon rinsho. Japanese journal of clinical medicine, 2019
Chronic inflammation is the common pathological basis for age-associated diseases. Chronic activation of basic inflammatory sates is known to associate with aging. Changes in immune system (immunosenescence), tissue microenvironment, such as the accumulation of cell debris, and systemic changes in metabolic and hormonal signals, likely contribute to ...
Yumiko, Oishi, Ichiro, Manabe
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Chronic inflammation is the common pathological basis for age-associated diseases. Chronic activation of basic inflammatory sates is known to associate with aging. Changes in immune system (immunosenescence), tissue microenvironment, such as the accumulation of cell debris, and systemic changes in metabolic and hormonal signals, likely contribute to ...
Yumiko, Oishi, Ichiro, Manabe
openaire +1 more source
NLRP3 inflammasome activation in inflammaging
Seminars in Immunology, 2018The process of aging is associated with the appearance of low-grade subclinical inflammation, termed inflammaging, that can accelerate age-related diseases. In Western societies the age-related inflammatory response can additionally be aggravated by an inflammatory response related to modern lifestyles and excess calorie consumption, a pathophysiologic
Latz, Eicke, Duewell, Peter
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Inflammaging aggravates stroke pathology
Nature Immunology, 2023Christian Schulz, Steffen Massberg
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The Journal of Investigative Dermatology, 2020
As global life expectancy continues to rise we are challenged with maintaining health into old age. One strategy is to target the chronic low level inflammation associated with aging, termed ‘inflammaging’. This is characterized by increased levels of circulating pro-inflammatory cytokines and a shift toward cellular senescence; changes that are ...
Pilkington, Suzanne +3 more
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As global life expectancy continues to rise we are challenged with maintaining health into old age. One strategy is to target the chronic low level inflammation associated with aging, termed ‘inflammaging’. This is characterized by increased levels of circulating pro-inflammatory cytokines and a shift toward cellular senescence; changes that are ...
Pilkington, Suzanne +3 more
openaire +1 more source