Results 81 to 90 of about 17,832 (233)

Emerging Vistas for the Nutraceutical Withania somnifera in Inflammaging

Pharmaceuticals
Inflammaging, a coexistence of inflammation and aging, is a persistent, systemic, low-grade inflammation seen in the geriatric population. Various natural compounds have been greatly explored for their potential role in preventing and treating ...
Vivek Basudkar, Gunjan Gujrati, Saiprasad Ajgaonkar, Manav Gandhi, Dilip Mehta, Sujit Nair   +5 more
doaj   +1 more source

Age‐related local versus systemic early phase wound healing dynamics following free gingival graft harvest

Journal of Periodontology, EarlyView.
Abstract Background Free palatal gingival grafts (FGG) are commonly harvested during mucogingival procedures. The present study investigates age‐related local and systemic early secondary wound healing outcomes, following FGG harvest in a rat model. Methods A 4.2 mm diameter defect was created in the palate of 24 younger (2 m) and 24 older (6 m) Wistar
Maayan Atzmon‐Shavit, Marilena Vered, Michael Saminsky, Liat Chaushu   +3 more
wiley   +1 more source

Changes in Dietary Intake and Adherence to the NU-AGE Diet Following a One-Year Dietary Intervention among European Older Adults—Results of the NU-AGE Randomized Trial [PDF]

, 2018
Background: The Mediterranean Diet has been proposed as an effective strategy to reduce inflammaging, a chronic low grade inflammatory status, and thus, to slow down the aging process.
Berendsen, Agnes A. M., Brzozowska, Anna, Caille, Aurélie, Cassidy, Aedin, Caumon, Elodie, de Groot, Lisette C. P. G. M., Feskens, Edith J. M., Franceschi, Claudio, Gillings, Rachel, Jennings, Amy, Malpuech-Brugere, Corinne, Ostan, Rita, Pietruszka, Barbara, Santoro, Aurelia, Stelmaszczyk-Kusz, Agnieszka, van de Rest, Ondine   +15 more
core   +3 more sources

Regulation of inflammAging

Bioinformation
The non-neuronal cholinergic system plays an important role in the modulation of immunity and in particular the control of the inflammatory response. The cholinergic anti-inflammatory pathway is mediated principally by the α7-nicotinic acetylcholine receptor (α7-nAChR) and its receptor-specific chaperone, resistance to inhibitors of cholinesterase (RIC)
Chiappelli, Francesco, Fotovat, Lily, Khakshooy, Allen, Oluwadara, Oluwadayo, Penhaskashi, Jaden   +4 more
openaire   +1 more source

Mapping the subgingival HerBiome and HisBiome over the human healthspan

Journal of Periodontology, EarlyView.
Abstract Background Understanding the intricate relationship between sex, age, and the oral microbiome is crucial for deciphering the onset and progression of numerous age‐related oral and systemic diseases. Methods Subgingival plaque was collected from 781 periodontally and systemically healthy females and 160 males spanning 0 to 80 years.
Rahul Nikam, Kazune Pax, Michelle Lee‐Scott Beverly, Purnima S. Kumar   +3 more
wiley   +1 more source

Quantitative proteomic analysis of age-related subventricular zone proteins associated with neurodegenerative disease. [PDF]

, 2016
Aging is characterized by a progressive decline in the function of adult tissues which can lead to neurodegenerative disorders. However, little is known about the correlation between protein changes in the subventricular zone (SVZ) and neurodegenerative ...
AV Molofsky, AY Maslov, B Winner, C Franceschi, C Lopez-Otin, C Stapnes, C Zhang, CM Dong, D Vilchez, DG Healy, ET Powers, F Doetsch, GL Ming, GP Dimri, H Inadera, H Koga, I Ziabreva, J Campisi, JJ Rodriguez, JJ Rodriguez, JM Savitt, KJ Davies, L Liu, LK Felzien, M De la Fuente, N Awasthi, N Chondrogianni, N Chondrogianni, N Chondrogianni, RA Signer, RM Seaberg, S Katyal, S Ohta, SA van den Berge, SZ Young, V Della-Maggiore, WR Markesbery   +36 more
core   +1 more source

Bridging Psychological Stress and Skin Cellular Aging: Flavonoids as a Dual‐Action Therapeutic Strategy

Phytotherapy Research, EarlyView.
ABSTRACT Psychological stress (or simply “stress”) is a major contributor to chronic disease worldwide, affecting 35% of the global population, including younger generations. Furthermore, it plays a significant role in human premature aging; hence, its detrimental effects on people's health compel us to comprehend and control the ways in which ...
Marco Duarte, Sílvia Santos Pedrosa, P. Raaj Khusial, Ana Raquel Madureira   +3 more
wiley   +1 more source

Identification of a prognostic signature for old-age mortality by integrating genome-wide transcriptomic data with the conventional predictors: the Vitality 90+ Study [PDF]

, 2014
Background Prediction models for old-age mortality have generally relied upon conventional markers such as plasma-based factors and biophysiological characteristics.
Antti Hervonen, Jani Raitanen, Juulia Jylhävä, Marja Jylhä, Mikko Hurme, Saara Marttila   +5 more
core   +2 more sources

Growth differentiation factor 15 mitigates lipotoxic steatosis by preserving mitochondrial morphodynamics and augmenting fatty acid oxidation in hepatocytes and liver organoids

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Growth differentiation factor 15 (GDF15) has emerged as a promising metabolic regulator with hepatoprotective properties in metabolic dysfunction‐associated steatotic liver disease (MASLD), yet its underlying mechanisms remain elusive.
Jia Li, Qi Zhou, Mengmeng Xia, Yakun Li, Junyu Wang, Manon Buist‐Homan, Vincent E. de Meijer, Hans Blokzijl, Klaas Nico Faber, Han Moshage   +9 more
wiley   +1 more source

Mindfulness meditation and improvement in depressive symptoms among Spanish- and English speaking adults: A randomized, controlled, comparative efficacy trial. [PDF]

, 2019
ObjectiveLatino immigrants experience acculturative stress and increased depression risk. Mindfulness meditation improves depressive symptoms, yet the vast majority of research has focused on English speaking populations.MethodsIn this randomized ...
Irwin, Michael R, Lopez-Maya, Eric, Olmstead, Richard   +2 more
core   +2 more sources