Results 191 to 200 of about 190,243 (379)

Vanillylacetone attenuates NLRP3 inflammasome mediated immune responses in murine bone marrow derived macrophages via NLRP3 alkylation

Journal of Functional Foods, 2020
Vanillylacetone (VA) is widely used as a food additive owing to its sweet flavour. In this study, we have reported for the first time that VA has an inhibitory role in inflammasome activation.
Han-Bi Kim, Sang-Chul Kwon, Xiao Sun, Mahbuba Akther, Jun-Hyuk Han, Tae-Yeon Kim, Tae-Bong Kang, Kwang-Ho Lee   +7 more
doaj  

Caspase-1 inflammasomes: choosing between death and taxis [PDF]

, 2007
Maya Saleh, Douglas R. Green
openalex   +1 more source

Sustained‐Release Photothermal Microneedles for Postoperative Incisional Analgesia and Wound Healing via Hydrogen Therapy

Advanced Science, EarlyView.
This study introduces a novel transdermal delivery system of molecular hydrogen for postoperative pain relief and wound healing. This system utilizes sustained‐release photothermal microneedles to integrate hydrogen‐releasing nanoparticles and temperature‐responsive microspheres, achieving acid‐responsive hydrogen release and controlled drug release ...
Aining Zhang, Xue Jiang, Bingrui Xiong, Jiayi Chen, Xin Liu, Siyuan Wang, Bofu Li, Mian Peng, Wei Li   +8 more
wiley   +1 more source

The Inflammasome Mediates UVB-Induced Activation and Secretion of Interleukin-1β by Keratinocytes [PDF]

, 2007
Laurence Feldmeyer, Martin Keller, Gisela Niklaus, Daniel Hohl, Sabine Werner, Hans‐Dietmar Beer   +5 more
openalex   +1 more source

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta.

Molecules and Cells, 2002
F. Martinon, K. Burns, J. Tschopp
semanticscholar   +1 more source

The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis

Nature, 2021
T. Fidler, Chenyi Xue, M. Yalcinkaya, B. Hardaway, Sandra Abramowicz, Tong Xiao, Wenli Liu, D. G. Thomas, M. Hajebrahimi, J. Pircher, C. Silvestre-Roig, Andriana G Kotini, Larry L. Luchsinger, Ying Wei, M. Westerterp, H. Snoeck, E. Papapetrou, C. Schulz, S. Massberg, O. Soehnlein, B. Ebert, R. Levine, M. Reilly, P. Libby, Nan Wang, A. Tall   +25 more
semanticscholar   +1 more source

Neutrophil Mobilization Triggers Microglial Functional Change to Exacerbate Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
These study underscores the pivotal role of neutrophil‐derived myeloid‐related protein 14 (MRP14) in the pathophysiology of acute ischemic stroke (AIS). MRP14 not only disrupts mitochondrial function, thereby inhibiting microglial phagocytosis of neutrophils, but also activates microglial pyroptosis, exacerbating neuroinflammation following AIS ...
Huijuan Jin, Zhifang Li, Senwei Tan, Qinghui Xiao, Qingcan Li, Jiao Ye, Yifan Zhou, Yan Wan, Qiang Liu, Bijoy K Menon, Bo Hu   +10 more
wiley   +1 more source

Type I interferon signaling is required for activation of the inflammasome during Francisella infection [PDF]

, 2007
Thomas Henry, Anna Brotcke, David S. Weiss, Lucinda J. Thompson, Denise M. Monack   +4 more
openalex   +1 more source

In Situ Programming of the Tumor Microenvironment to Alleviate Immunosuppression for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
cmExoaCD11b induced the repolarization of immunosuppressive M2 macrophages into pro‐inflammatory M1 phenotype, thereby promoting the proliferation and activation of CD8+ T cells and reversing the immunosuppressive state of the tumor microenvironment.
Man Sun, Huan Zhang, Yarui Ma, Simiao Wang, Jiayi Chen, Yaxin Cui, Yun Zhang, Siyuan Hu, Dan Zhou, Pengchen Zhang, Yahui Liu, Betty Y.S. Kim, Wen Jiang, Xiaobing Wang, Zhaogang Yang   +14 more
wiley   +1 more source

NALP3 Forms an IL-1β-Processing Inflammasome with Increased Activity in Muckle-Wells Autoinflammatory Disorder

, 2004
Laetitia Agostini, Fabio Martinon, Kimberly Burns, Michael McDermott, Philip N. Hawkins, Jürg Tschopp   +5 more
openalex   +1 more source