Results 221 to 230 of about 190,243 (379)
This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo+10 more
wiley +1 more source
Inflammasomes are Differentially Expressed in Cardiovascular and other Tissues [PDF]
Yong Yin+6 more
openalex +1 more source
Mechanism and Regulation of NLRP3 Inflammasome Activation.
Yuan He, H. Hara, G. Núñez
semanticscholar +1 more source
The G‐CS/MSN drug delivery system enhances intervertebral disc repair through sequential drug release. Abstract Intervertebral disc degeneration (IDD) is characterized by an inflammatory environment and dysregulation of the extracellular matrix metabolism (ECM).
Xiangzhen Kong+12 more
wiley +1 more source
Inflammasome-Associated Nucleotide-Binding Domain, Leucine-Rich Repeat Proteins and Inflammatory Diseases [PDF]
Sushmita Jha, Jenny P.‐Y. Ting
openalex +1 more source
Naturally derived biomembrane nanostructures by mimicking evolutionarily optimized biological architectures could effectively suppress tumor growth and have emerged as a compelling strategy in translational biomedicine. This review provides a systematic overview of rational design and underlying antitumor therapeutic mechanisms of mammalian cells ...
Xiaodan Wei+10 more
wiley +1 more source
ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome
Sanjeev Mariathasan
openalex +1 more source
An Essential Role for the NLRP3 Inflammasome in Host Defense against the Human Fungal Pathogen Candida albicans [PDF]
Amy G. Hise+6 more
openalex +1 more source
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases
Rebecca C. Coll+21 more
semanticscholar +1 more source
Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang+6 more
wiley +1 more source