Results 181 to 190 of about 45,312 (295)

The Role of NLRP1, AIM2 and MEFV Inflammasomes in the High-Intensity Interval Training of Individuals With Obesity. [PDF]

Immunology
Silveira ALPA, Abreu DA, Musto ALS, Nali LHDS, Amaral JBD, Bachi ALL, Shio MT, Rezende-Teixeira P, França CN.   +8 more
europepmc   +1 more source

Resveratrol Ameliorates Allergic Rhinitis by Activating SIRT1 to Disrupt the Mitochondrial ROS‐Inflammation Vicious Cycle

Flavour and Fragrance Journal, EarlyView.
This study demonstrates that resveratrol alleviates allergic rhinitis by activating SIRT1, thereby disrupting the mitochondrial ROS‐inflammatory cycle, improving mitochondrial function, promoting anti‐inflammatory M2 macrophage polarisation, and reducing epithelial oxidative damage.
Xinyu Zhou, Yi Yue, Wenwen Qi, Wenqing Zhu, Xinran Liu, Rongcui Sui, Xuanchen Zhou   +6 more
wiley   +1 more source

Special Issue "Immunomodulatory Molecules in Cancer". [PDF]

Int J Mol Sci
Pantouris G.
europepmc   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Pulmonary Vascular Signaling in Pulmonary Hypertension: Potential Role of Endothelial Ca²⁺ Signaling in Cellular Senescence and Inflammasome Activation. [PDF]

Arterioscler Thromb Vasc Biol
Wang WT, Li X, Wang T, Ferrizzi SA, Avchalumov Y, Thistlethwaite PA, Makino A, Yuan JX.   +7 more
europepmc   +1 more source

["The inflammasomes"].

Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2012
Inflammation is a host adaptational response to cell injury caused by various exogenous and endogenous stimuli. IL-1β, which is an important proinflammatory cytokine secreted at the site of cellular injury, plays an important role in inflammation. Inflammasome is an intracellular multi-protein complex that mediates caspase-1-dependent processing of IL ...
openaire   +1 more source

Beyond Gut Modulation: A Critical Review of the Therapeutic Potential, Safety, and Clinical Prospects of Natural Polysaccharides for IBD

Food Safety and Health, EarlyView.
In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso, A. M. Abd El‐Aty, Kwaku Amoah, Xianghong Ju   +3 more
wiley   +1 more source

Tellimagrandin II Stimulates Inflammasomes by Causing an Accumulation of 3-Aminopropanal, Which Promotes Apoptosis of Endometriotic Cells While Inhibiting Invasion. [PDF]

J Inflamm Res
Fan W, Zhang Y, Zhao R.
europepmc   +1 more source

Gut microbiota and postoperative complications in colorectal surgery and its potential association with intestinal permeability and NLRP6 inflammasome. [PDF]

Front Immunol
Buitrago-Ruiz M, Arias-Sánchez C, Asensio-López MM, Martínez-García JJ, Soria-Aledo V, Valero-Navarro G, Cuevas S.   +6 more
europepmc   +1 more source

Regulatory Roles of Noncanonical Inflammasomes in Diabetes Mellitus and Diabetes-Associated Complications. [PDF]

Int J Mol Sci
Yi YS.
europepmc   +1 more source