Results 21 to 30 of about 3,006,442 (287)

Resolution of MoS2 nanosheets-induced pulmonary inflammation driven by nanoscale intracellular transformation and extracellular-vesicle shuttles [PDF]

, 2022
Pulmonary exposure to some engineered nanomaterials can cause chronic lesions as a result of unresolved inflammation. Among two-dimensional (2D) nanomaterials and graphene, MoS2 have received tremendous attention in optoelectronics and nanomedicine. Here
Nathaly, Ortiz Peña, Hervé , Hillaireau, Kondareddy , Cherukula, Sarah , Razafindrakoto, Cécilia, Ménard Moyon, Amanda K. A. , Silva, Florence , Gazeau, Alberto , Bianco, Benjamin , Even, Shiyuan , Peng, Elias , Fattal, Ding-Kun , Ji, Damien , Alloyeau   +12 more
core   +1 more source

A 17-kDa Fragment of Lactoferrin Associates With the Termination of Inflammation and Peptides Within Promote Resolution

Frontiers in Immunology, 2018
During the resolution of inflammation, macrophages engulf apoptotic polymorphonuclear cells (PMN) and can accumulate large numbers of their corpses. Here, we report that resolution phase macrophages acquire the neutrophil-derived glycoprotein lactoferrin
Aviv Lutaty, Aviv Lutaty, Soaad Soboh, Soaad Soboh, Sagie Schif-Zuck, Sagie Schif-Zuck, Orly Zeituni-Timor, Orly Zeituni-Timor, Ran Rostoker, Ran Rostoker, Malgorzata J. Podolska, Christine Schauer, Martin Herrmann, Luis E. Muñoz, Amiram Ariel, Amiram Ariel   +15 more
doaj   +1 more source

Downregulation of Mcl-1 has anti-inflammatory pro-resolution effects and enhances bacterial clearance from the lung [PDF]

, 2014
Phagocytes not only coordinate acute inflammation and host defense at mucosal sites, but also contribute to tissue damage. Respiratory infection causes a globally significant disease burden and frequently progresses to acute respiratory distress syndrome,
Tait, M A, Robb, C T, Haslett, C, Duffin, R, Fox, S, Rossi, A G, Dorward, D A, Lucas, C D; id_orcid, Allen, K C, Hirani, N, Marwick, J A   +10 more
core   +1 more source

Adhesion molecule-dependent mechanisms regulate the rate of macrophage clearance during the resolution of peritoneal inflammation [PDF]

, 2002
Macrophage clearance is essential for the resolution of inflammation. Much is known about how monocytes enter the inflammatory site but little is known about how resultant macrophages are cleared. We have previously demonstrated that macrophage clearance
Mutsaers, SE, Bottoms, S, Cooksley, H, Helen Cauldwell, Bellingan, GJ, Christopher Haslett, Xu, P, Haslett, C, Geoffrey John Laurent, Steven Eugene Mutsaers, Anthony Shock, Laurent, GJ, Ping Xu, Stephen Bottoms, Cauldwell, H, Shock, A, Helen Cooksley, Geoffrey John Bellingan   +17 more
core   +1 more source

MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure [PDF]

, 2018
Objective: Acute liver failure (ALF) is characterised by overwhelming hepatocyte death and liver inflammation with massive infiltration of myeloid cells in necrotic areas.
Curbishley, S.M., Khamri, W., Patel, V.C., Pop, O.T., Wilson, I.D., Triantafyllou, E., Ma, Y., Davies, S.P., Dargue, R., Abeles, R.D., Bernsmeier, C., Coen, M., Antoniades, C.G., Liaskou, E., Woollard, K.J., Adams, D.H., Petts, G., Wilhelm, A., Tickle, J., Wendon, J., Stamataki, Z., Possamai, L.A., Weston, C.J., Thursz, M.R., Quaglia, A., Yuksel, M., Singanayagam, A.   +26 more
core   +1 more source

Apoptosis is essential for neutrophil functional shutdown and determines tissue damage in experimental pneumococcal meningitis. [PDF]

, 2009
During acute bacterial infections such as meningitis, neutrophils enter the tissue where they combat the infection before they undergo apoptosis and are taken up by macrophages.
Häcker Georg, Bianca Obermaier, Georg Häcker, Robert Paul, Hans Häcker, Obermaier, Bianca, Paul Robert, Frankenberg, Tobias, Koedel, Uwe, Uwe Koedel, Frankenberg Tobias, Paul, Robert, Susanne Kirschnek, Kirschnek, Susanne, Tobias Frankenberg, Kirschnek Susanne, Obermaier Bianca, Koedel Uwe, Häcker, Hans, Häcker, Georg, Häcker Hans   +20 more
core   +2 more sources

Apoptosis in resolution of inflammation [PDF]

Journal of Leukocyte Biology, 1997
Abstract The last few years have seen the accumulation of compelling evidence that apoptosis (programmed cell death) plays a major role in promoting resolution of the acute inflammatory response. Neutrophils are constitutively programmed to undergo apoptosis, which limits their pro-inflammatory potential and leads to rapid, specific, and
openaire   +3 more sources

Resolving acute inflammation; what happens when inflammation goes haywire? How can it get back in line?

, 2022
Within this chapter we discuss the mechanisms that drive inflammation resolution and consider the possible reasons for the failure of resolution responses and chronicity of inflammation.
Norling, LV, Cecconello, C, Clària Ribas, P   +2 more
core   +1 more source

Glucocorticoid-Induced Leucine Zipper Alleviates Lung Inflammation and Enhances Bacterial Clearance during Pneumococcal Pneumonia

Cells, 2022
Pneumonia is a leading cause of morbidity and mortality. While inflammation is a host protective response that ensures bacterial clearance, a finely regulated response is necessary to prevent bystander tissue damage.
Jéssica Amanda Marques Souza, Antônio Felipe S. Carvalho, Lais C. Grossi, Isabella Zaidan, Leonardo Camilo de Oliveira, Juliana P. Vago, Camila Cardoso, Marina G. Machado, Geovanna V. Santos Souza, Celso Martins Queiroz-Junior, Eric F. Morand, Stefano Bruscoli, Carlo Riccardi, Mauro M. Teixeira, Luciana P. Tavares, Lirlândia P. Sousa   +15 more
doaj   +1 more source

Molecular dynamics of inflammation resolution: therapeutic implications. [PDF]

Front Cell Dev Biol
Inflammation is a critical part of innate immune response that is essential for exclusion of harmful stimuli and restoration of tissue homeostasis.
Soliman AM, Soliman M, Shah SSH, Baig HA, Gouda NS, Alenezi BT, Alenezy A, Hegazy AMS, Jan M, Eltom EH.   +9 more
europepmc   +2 more sources