Results 11 to 20 of about 948,572 (352)

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases. [PDF]

Nature, 2019
Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect several million individuals worldwide. Crohn's disease and ulcerative colitis are complex diseases that are heterogeneous at the clinical, immunological, molecular,
Ajami, Nadim J, Ananthakrishnan, Ashwin N, Andrews, Elizabeth, Arze, Cesar, Avila-Pacheco, Julian, Bonham, Kevin S, Braun, Jonathan, Brislawn, Colin J, Casero, David, Clish, Clary B, Courtney, Holly, Denson, Lee A, Franzosa, Eric A, Gonzalez, Antonio, Graeber, Thomas G, Hall, A Brantley, Huttenhower, Curtis, IBDMDB Investigators, Jansson, Janet K, Knight, Rob, Kugathasan, Subra, Lake, Kathleen, Landers, Carol J, Lloyd-Price, Jason, Mallick, Himel, McGovern, Dermot PB, Petrosino, Joseph F, Plichta, Damian R, Poon, Tiffany W, Prasad, Mahadev, Rahnavard, Gholamali, Sauk, Jenny, Schirmer, Melanie, Shungin, Dmitry, Stappenbeck, Thaddeus S, Vlamakis, Hera, Vázquez-Baeza, Yoshiki, White, Richard A, Winter, Harland S, Xavier, Ramnik J   +39 more
core   +2 more sources

History of Inflammatory Bowel Diseases [PDF]

Journal of Clinical Medicine, 2019
Inflammatory bowel diseases (IBD) are characterized by chronic inflammation of the intestinal mucosa and unknown etiology. In this review, we identified three main eras in the IBD history. Between the 19th and the 20th century, the primary task had been the definition of the diagnostic criteria in order to differentiate the new entity from intestinal ...
Giovanni Clemente Actis, Rinaldo Pellicano, Sharmila Fagoonee, Davide Giuseppe Ribaldone   +3 more
openaire   +5 more sources

Inflammatory Bowel Diseases and Gut Microbiota

International Journal of Molecular Sciences, 2023
Inflammatory bowel disease (IBD) is an inflammatory disease of the gastrointestinal tract, the incidence of which has rapidly increased worldwide, especially in developing and Western countries.
Yuri Haneishi, Yuma Furuya, Mayu Hasegawa, A. Picarelli, M. Rossi, J. Miyamoto   +5 more
semanticscholar   +1 more source

The Role of Enterobacteriaceae in Gut Microbiota Dysbiosis in Inflammatory Bowel Diseases

Microorganisms, 2021
Inflammatory bowel diseases (IBDs) are a group of chronic gastrointestinal inflammatory diseases with unknown etiology. There is a combination of well documented factors in their pathogenesis, including intestinal microbiota dysbiosis.
Valerio Baldelli, F. Scaldaferri, L. Putignani, F. Del Chierico   +3 more
semanticscholar   +1 more source

The Gut Microbiome and Inflammatory Bowel Diseases.

Annual Review of Medicine, 2021
Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental factors, and gut microbiota, where each is necessary but not sufficient to cause disease.
Yue Shan, Mirae Lee, E. Chang
semanticscholar   +1 more source

Dermatological Manifestations in Inflammatory Bowel Diseases

Journal of Clinical Medicine, 2021
Inflammatory bowel diseases (IBDs) may be associated with extra-intestinal manifestations. Among these, mucocutaneous manifestations are relatively frequent, often difficult to diagnose and treat, and may complicate the course of the underlying disease ...
E. Antonelli, G. Bassotti, M. Tramontana, K. Hansel, L. Stingeni, S. Ardizzone, G. Genovese, A. Marzano, G. Maconi   +8 more
semanticscholar   +1 more source

Crohn’s disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome

Genome Medicine, 2022
Background Crohn’s disease (CD) patients demonstrate distinct intestinal microbial compositions and metabolic characteristics compared to unaffected controls. However, the impact of inflammation and underlying genetic risk on these microbial profiles and
Jonathan P. Jacobs, Maryam Goudarzi, Venu Lagishetty, Dalin Li, Tytus Mak, Maomeng Tong, Paul Ruegger, Talin Haritunians, Carol Landers, Philip Fleshner, Eric Vasiliauskas, Andrew Ippoliti, Gil Melmed, David Shih, Stephan Targan, James Borneman, Albert J. Fornace, Dermot P. B. McGovern, Jonathan Braun   +18 more
doaj   +1 more source

Inflammatory Bowel Diseases (IBD) (Inflammatory Bowel Diseases and the Microbiome: Searching the Crime Scene for Clues).

Gastroenterology, 2020
Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial, immunological, and genetic factors. Alterations in the gut microbiota have been associated with development and progression of IBD, but it is not clear which ...
Mirae Lee, E. Chang
semanticscholar   +1 more source

PTPN2 gene variants are associated with susceptibility to both Crohn's disease and ulcerative colitis supporting a common genetic disease background. [PDF]

, 2012
Genome-wide association studies identified PTPN2 (protein tyrosine phosphatase, non-receptor type 2) as susceptibility gene for inflammatory bowel diseases (IBD).
Beigel, Florian, Brand, Stephan, Czamara, Darina, Diegelmann, Julia, Friedrich, Matthias, Glas, Jürgen, Göke, Burkhard, Karbalai, Nazanin, Ochsenkühn, Thomas, Olszak, Torsten, Seiderer, Julia, Stallhofer, Johannes, Steib, Christian, Tillack, Cornelia, Wagner, Johanna, Wetzke, Martin   +15 more
core   +10 more sources

Development and evaluation of a risk assessment tool to improve clinical triage accuracy for colonoscopic investigations

BMC Cancer, 2018
Background Gastroenterology Departments at hospitals within Australia receive thousands of General Practitioner (GP)-referral letters for gastrointestinal investigations every month. Many of these requests are for colonoscopy. This study aims to evaluate
Anton R. Lord, Lisa A. Simms, Allison Brown, Katherine Hanigan, Krupa Krishnaprasad, Belinda Schouten, Anthony R. Croft, Mark N. Appleyard, Graham L. Radford-Smith   +8 more
doaj   +1 more source