Results 11 to 20 of about 1,070,166 (331)

The Role of Enterobacteriaceae in Gut Microbiota Dysbiosis in Inflammatory Bowel Diseases

Microorganisms, 2021
Inflammatory bowel diseases (IBDs) are a group of chronic gastrointestinal inflammatory diseases with unknown etiology. There is a combination of well documented factors in their pathogenesis, including intestinal microbiota dysbiosis.
Valerio Baldelli, F. Scaldaferri, L. Putignani, F. Del Chierico   +3 more
semanticscholar   +1 more source

The Gut Microbiome and Inflammatory Bowel Diseases.

Annual Review of Medicine, 2021
Inflammatory bowel diseases (IBD) arise from a convergence of genetic risk, environmental factors, and gut microbiota, where each is necessary but not sufficient to cause disease.
Yue Shan, Mirae Lee, E. Chang
semanticscholar   +1 more source

DR3 Regulates Intestinal Epithelial Homeostasis and Regeneration After Intestinal Barrier InjurySummary

Cellular and Molecular Gastroenterology and Hepatology, 2023
Background & Aims: Tumor necrosis factor (TNF) superfamily member tumor necrosis factor–like protein 1A (TL1A) has been associated with the susceptibility and severity of inflammatory bowel diseases. However, the function of the tumor necrosis factor–
Yosuke Shimodaira, Shyam K. More, Hussein Hamade, Anna Y. Blackwood, Jay P. Abraham, Lisa S. Thomas, Jordan H. Miller, Dalton T. Stamps, Sofi L. Castanon, Noam Jacob, Connie W.Y. Ha, Suzanne Devkota, David Q. Shih, Stephan R. Targan, Kathrin S. Michelsen   +14 more
doaj   +1 more source

Dermatological Manifestations in Inflammatory Bowel Diseases

Journal of Clinical Medicine, 2021
Inflammatory bowel diseases (IBDs) may be associated with extra-intestinal manifestations. Among these, mucocutaneous manifestations are relatively frequent, often difficult to diagnose and treat, and may complicate the course of the underlying disease ...
E. Antonelli, G. Bassotti, M. Tramontana, K. Hansel, L. Stingeni, S. Ardizzone, G. Genovese, A. Marzano, G. Maconi   +8 more
semanticscholar   +1 more source

The effects of inflammatory bowel disease on caregivers: significant burden and loss of productivity

BMC Health Services Research, 2020
Background Caregiver burden is the emotional, physical, practical, and/or financial burden associated with taking care of a patient with a chronic condition.
Aria Zand, Brian J. Kim, Welmoed K. van Deen, Zachary Stokes, Anya Platt, Shelby O’Hara, Harrison Khong, Daniel W. Hommes   +7 more
doaj   +1 more source

Crohn’s disease in endoscopic remission, obesity, and cases of high genetic risk demonstrates overlapping shifts in the colonic mucosal-luminal interface microbiome

Genome Medicine, 2022
Background Crohn’s disease (CD) patients demonstrate distinct intestinal microbial compositions and metabolic characteristics compared to unaffected controls. However, the impact of inflammation and underlying genetic risk on these microbial profiles and
Jonathan P. Jacobs, Maryam Goudarzi, Venu Lagishetty, Dalin Li, Tytus Mak, Maomeng Tong, Paul Ruegger, Talin Haritunians, Carol Landers, Philip Fleshner, Eric Vasiliauskas, Andrew Ippoliti, Gil Melmed, David Shih, Stephan Targan, James Borneman, Albert J. Fornace, Dermot P. B. McGovern, Jonathan Braun   +18 more
doaj   +1 more source

Inflammatory Bowel Diseases (IBD) (Inflammatory Bowel Diseases and the Microbiome: Searching the Crime Scene for Clues).

Gastroenterology, 2020
Inflammatory bowel diseases (IBD) develop via convergence of environmental, microbial, immunological, and genetic factors. Alterations in the gut microbiota have been associated with development and progression of IBD, but it is not clear which ...
Mirae Lee, E. Chang
semanticscholar   +1 more source

Development and evaluation of a risk assessment tool to improve clinical triage accuracy for colonoscopic investigations

BMC Cancer, 2018
Background Gastroenterology Departments at hospitals within Australia receive thousands of General Practitioner (GP)-referral letters for gastrointestinal investigations every month. Many of these requests are for colonoscopy. This study aims to evaluate
Anton R. Lord, Lisa A. Simms, Allison Brown, Katherine Hanigan, Krupa Krishnaprasad, Belinda Schouten, Anthony R. Croft, Mark N. Appleyard, Graham L. Radford-Smith   +8 more
doaj   +1 more source

A Nucleotide Analog Prevents Colitis-Associated Cancer via Beta-Catenin Independently of Inflammation and AutophagySummary

Cellular and Molecular Gastroenterology and Hepatology, 2021
Background & Aims: Chronic bowel inflammation increases the risk of colon cancer; colitis-associated cancer (CAC). Thiopurine treatments are associated with a reduction in dysplasia and CAC in inflammatory bowel disease (IBD).
Yong Hua Sheng, Rabina Giri, Julie Davies, Veronika Schreiber, Saleh Alabbas, Ramya Movva, Yaowu He, Andy Wu, John Hooper, Brett McWhinney, Iulia Oancea, Gregor Kijanka, Sumaira Hasnain, Andrew J. Lucke, David P. Fairlie, Michael A. McGuckin, Timothy H. Florin, Jakob Begun   +17 more
doaj   +1 more source

Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases

Frontiers in Immunology, 2019
Ulcerative colitis (UC) and Crohn's disease (CD), collectively known as Inflammatory Bowel Diseases (IBD), are caused by a complex interplay between genetic, immunologic, microbial and environmental factors.
Daniela Parada Venegas, M. De la Fuente, G. Landskron, María-Julieta González, R. Quera, G. Dijkstra, H. Harmsen, K. Faber, M. Hermoso   +8 more
semanticscholar   +1 more source