Results 101 to 110 of about 11,191,535 (322)
FEBS Letters, EarlyView.Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Ações de pesquisa e extensão no projeto laboratório de tecnologias intelectuais
TransinformaçãoEste trabalho apresenta os primeiros resultados do Projeto Laboratório de Tecnologias Intelectuais, em desenvolvimento mediante parceria entre o Departamento de Ciência da Informação e o Programa de Pós-Graduação em Ciência da Informação da Universidade ...
Isa Maria Freire +3 more
doaj
Informing Evidence Based Decisions: Usage Statistics for Online Journal Databases
Evidence Based Library and Information Practice, 2017 Objective – The primary objective was to examine online journal database usage statistics for a provincial ministry of health in the context of evidence based decision-making. In addition, the study highlights implementation of the Journal Access Centre (
Alexei Botchkarev
doaj +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
FEBS Letters, EarlyView.Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
FEBS Letters, EarlyView.Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Symposium on information science. VI. Form and utilization of bacteriological information in a select document collection [PDF]
, 1965 W M Bejuki
openalex +1 more source
Web 2.1 : Toward a large and qualitative participation on the Web
Journal of Information and Organizational Sciences, 2009 This article presents the results of research done on Web 2.0 within the School of Information Sciences ESI. It aims to study the behavior of different academic actors who deal with information, among whom we cite teachers, students of masters and ...
Boubker Sbihi +2 more
doaj
Molecular Oncology, EarlyView.Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka +10 more
wiley +1 more source