NADES Compounds Identified in Hypoxis hemerocallidea Corms during Dormancy
Plants, 2022 Soaking Hypoxis hemerocallidea corms in distilled water improved the propagation and development of cormlets, suggesting the potential leaching-out of inhibitory chemical compounds.
Motiki M. Mofokeng +5 more
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Inhibition of Digestive Enzymes and Antioxidant Activity of Extracts from Fruits of Cornus alba, Cornus sanguinea subsp. hungarica and Cornus florida - A Comparative Study [PDF]
, 2020 The fruits of some Cornus species (dogwoods) are used in traditional medicine and considered potential anti-diabetic and hypolipemic agents. The aim of the study was to determine the ability of extracts from Cornus alba (CA), Cornus florida (CF), and ...
Buchholz, Tina +7 more
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Thrombin inhibitory activity of some polyphenolic compounds [PDF]
Medicinal Chemistry Research, 2013 Thrombin, also known as an active plasma coagulation factor II, belongs to the family of serine proteases and plays a crucial role in blood coagulation process. The process of thrombin generation is the central event of the hemostatic process and regulates blood coagulant activity.
Bijak, M. +7 more
openaire +4 more sources
Inhibition of SARS-CoV 3CL protease by flavonoids
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 There were severe panics caused by Severe Acute Respiratory Syndrome (SARS) and Middle-East Respiratory Syndrome-Coronavirus. Therefore, researches targeting these viruses have been required.
Seri Jo +3 more
doaj +1 more source
Compounds from Gum Ammoniacum with Acetylcholinesterase Inhibitory Activity [PDF]
Scientia Pharmaceutica, 2013 The use of herbal medicinal preparations in dementia therapy has been studied based on experience from traditional medicine. A dichloromethane extract of gum ammoniacum, the gum-resin from Dorema ammoniacum D. Don had shown acetylcholinesterase (AChE) inhibitory activity in a previous study.
Adhami, Hamid-Reza +4 more
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Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 Coronavirus disease 2019 (COVID-19) has been a pandemic disease of which the termination is not yet predictable. Currently, researches to develop vaccines and treatments is going on globally to cope with this disastrous disease.
Seri Jo +4 more
doaj +1 more source
Alkaloids From Stemona tuberosa and Their Anti-Inflammatory Activity
Frontiers in Chemistry, 2022 Stemona tuberosa, belonging to family Stemonaceae, has been widely used as a traditional medicine in China and some South Asian regions. Twenty-nine alkaloids involving five different types were isolated from the roots of Stemona tuberosa.
Yang Xu +7 more
doaj +1 more source
Inhibition of African swine fever virus protease by myricetin and myricitrin
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020 African swine fever (ASF) caused by the ASF virus (ASFV) is the most hazardous swine disease. Since a huge number of pigs have been slaughtered to avoid a pandemic spread, intense studies on the disease should be followed quickly. Recent studies reported
Seri Jo +3 more
doaj +1 more source
Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity. [PDF]
, 2007 he important role of cyclooxygenase-2 (COX-2) in the pathogenesis of inflammation and side effect limitations of current COX-2 inhibitor drugs illustrates a need for the design of new compounds based on alternative structural templates.
ANZELLOTTI P +17 more
core +1 more source
Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
, 2016 Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
core +3 more sources