Results 101 to 110 of about 71,654 (304)
BiomedicinesBackground/Objectives: Norepinephrine (NE) plays a crucial role in modulating cognitive processes via α2A-adrenoceptors (α2A-ARs) within the prefrontal cortex (PFC), an essential brain region responsible for higher cognitive functions.
Yaru Wei +5 more
doaj +1 more source
Advanced Science, EarlyView.A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang +10 more
wiley +1 more source
The general anaesthetic etomidate inhibits the excitability of mouse thalamocortical relay neurons by modulating multiple modes of GABAA receptor-mediated inhibition [PDF]
, 2014 Modulation of thalamocortical (TC) relay neuron function has been implicated in the sedative and hypnotic effects of general anaesthetics. Inhibition of TC neurons is mediated predominantly by a combination of phasic and tonic inhibition, together with a
Herd, Murray B. +5 more
core +1 more source
Photonic‐Enabled Energy‐Efficient Transparent Neuromorphic Computing Devices: A Review
Advanced Science, EarlyView.Transparent photonic neuromorphic computing devices merge optics and brain‐inspired computing to overcome von Neumann bottlenecks with ultrafast, low‐energy processing. By exploiting transparent oxides, 2D materials, phase‐change materials, and hybrid heterostructures, these platforms enable photonic synapses, memory, and logic for see‐through edge ...
Shuvaraj Ghosh +8 more
wiley +1 more source
Dynamic encoding of natural luminance sequences by LGN bursts [PDF]
, 2006 In the lateral geniculate nucleus (LGN) of the thalamus, visual stimulation produces two distinct types of responses known as tonic and burst. Due to the dynamics of the T-type Ca2+ channels involved in burst generation, the type of response evoked by a ...
Chong Weng +17 more
core +1 more source
Scientific Reports, 2017 We present a novel, all-electric approach to record and to precisely control the activity of tens of individual presynaptic neurons. The method allows for parallel mapping of the efficacy of multiple synapses and of the resulting dynamics of postsynaptic
David Jäckel +7 more
doaj +1 more source
Advanced Science, EarlyView.Here, we present an optoelectronic synaptic memtransistor (OSMT) integrating photoresponsive IGZO with contact‐engineered HfO2, enabling electrically and optically tunable synaptic weights. The device demonstrates broad range of tunable conductance states and array‐level image processing, highlighting its potential for intelligent machine vision ...
Donghyun Kang +6 more
wiley +1 more source
The P2X receptor mediated regulation of inhibitory synaptic transmission [PDF]
In the central nervous system ATP can be released by neurons and glial cells through similar pathways as other neurotransmitters. Extracellular ATP targets P2X purinoreceptors, causing an influx of Ca2+ ions which transmit very important messages for ...
Andrew-Adiamah, Jemma
core
Live-cell imaging of receptors around postsynaptic membranes. [PDF]
, 2013 This protocol describes how to image the trafficking of glutamate receptors around excitatory postsynaptic membrane formed on an adhesion protein-coated glass surface.
Hirano, Tomoo +5 more
core +1 more source
Subcellular Imbalances in Synaptic Activity
Cell Reports, 2016 The dynamic interactions between synaptic excitation and inhibition (E/I) shape membrane potential fluctuations and determine patterns of neuronal outputs; however, the spatiotemporal organization of these interactions within a single cell is poorly ...
Naoya Takahashi +3 more
doaj +1 more source