Results 141 to 150 of about 521,946 (359)

Integrated brain on a chip and automated organ‐on‐chips systems

open access: yesInterdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023
Organ‐on‐chips (OOCs) related to brain functions have been used in drug development and disease simulation in vitro. However, modeling of complex biological systems remains a major challenge. In this paper, the compositions of the OOCs are optimized, and an automatic integrated system model is designed. It is expected to boost life science research and
Zhe Li   +3 more
wiley   +1 more source

Morphine Differentially Alters the Synaptic and Intrinsic Properties of D1R- and D2R-Expressing Medium Spiny Neurons in the Nucleus Accumbens

open access: yesFrontiers in Synaptic Neuroscience, 2019
Exposure to opioids reshapes future reward and motivated behaviors partially by altering the functional output of medium spiny neurons (MSNs) in the nucleus accumbens shell.
Dillon S. McDevitt   +3 more
doaj   +1 more source

Ionic Permeability of the Inhibitory Postsynaptic Membrane of Lobster Muscle Fibers

open access: yesThe Journal of General Physiology, 1969
Reversal potentials (E IPSP) of the inhibitory postsynaptic potential and the membrane resting potentials (EM) of lobster muscle fibers were determined with intracellular recording under a variety of ionic conditions.
F. Motokizawa, J. Reuben, H. Grundfest
semanticscholar   +1 more source

Bioinspired Adaptive Neuron Enabled by Self‐powered Optoelectronic Memristor and Threshold Switching Memory for Neuromorphic Visual System

open access: yesAdvanced Science, EarlyView.
The self‐powered optoelectronic memristor based on ZnO/WOx heterojunction is developed, exhibiting the visual adaptation functions of desensitization and Weber's law. A bioinspired visual adaptive neuron is constructed, capable of converting light stimuli into dynamic spike trains.
Yankun Cheng   +8 more
wiley   +1 more source

Altered Amygdala Excitation and CB1 Receptor Modulation of Aggressive Behavior in the Neuroligin-3R451C Mouse Model of Autism

open access: yesFrontiers in Cellular Neuroscience, 2018
Understanding neuronal mechanisms underlying aggression in patients with autism spectrum disorder (ASD) could lead to better treatments and prognosis.
Suzanne Hosie   +8 more
doaj   +1 more source

Spike timing precision and neural error correction: local behavior [PDF]

open access: yesNeural Computation, v. 17, n. 7, 1577-1601, 2005, 2005
The effects of spike timing precision and dynamical behavior on error correction in spiking neurons were investigated. Stationary discharges -- phase locked, quasiperiodic, or chaotic -- were induced in a simulated neuron by presenting pacemaker presynaptic spike trains across a model of a prototypical inhibitory synapse.
arxiv  

A biophysical observation model for field potentials of networks of leaky integrate-and-fire neurons

open access: yes, 2012
We present a biophysical approach for the coupling of neural network activity as resulting from proper dipole currents of cortical pyramidal neurons to the electric field in extracellular fluid.
Graben, Peter beim, Rodrigues, Serafim
core   +2 more sources

Implementing Multimodal Hardware Security with 2D α‐In2Se3 Ferroelectric Transistor

open access: yesAdvanced Science, EarlyView.
A multimodal secure transistor‐integrated in‐memory sensing and computing architecture is demonstrated by leveraging its electronic and optoelectronic synaptic behaviors. Key security primitives, such as anticounterfeiting, watermarking, logic locking, and camouflaging, are implemented within a compact single‐transistor structure, providing a scalable ...
Xinwei Zhang   +11 more
wiley   +1 more source

Environmental exposure of the general population to cadmium as a risk factor of the damage to the nervous system: A critical review of current data

open access: yesJournal of Applied Toxicology, Volume 43, Issue 1, Page 66-88, January 2023., 2023
Abstract Nowadays, more and more attention has been focused on the risk of the neurotoxic action of cadmium (Cd) under environmental exposure. Due to the growing incidence of nervous system diseases, including neurodegenerative changes, and suggested involvement of Cd in their aetiopathogenesis, this review aimed to discuss critically this element ...
Agnieszka Ruczaj   +1 more
wiley   +1 more source

Molecular Specialization of GABAergic Synapses on the Soma and Axon in Cortical and Hippocampal Circuit Function and Dysfunction

open access: yesFrontiers in Molecular Neuroscience, 2019
The diversity of inhibitory interneurons allows for the coordination and modulation of excitatory principal cell firing. Interneurons that release GABA (γ-aminobutyric acid) onto the soma and axon exert powerful control by virtue of proximity to the site
April Contreras   +2 more
doaj   +1 more source

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