Postsynaptic activity of inhibitory neurons evokes hemodynamic fMRI responses [PDF]
NeuroImage, 2021 Functional MRI responses are localized to the synaptic sites of evoked inhibitory neurons, but it is unknown whether, or by what mechanisms, these neurons initiate functional hyperemia.
Alexander John Poplawsky +4 more
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Imperfect space clamp permits electrotonic interactions between inhibitory and excitatory synaptic conductances, distorting voltage clamp recordings. [PDF]
PLoS ONE, 2011 The voltage clamp technique is frequently used to examine the strength and composition of synaptic input to neurons. Even accounting for imperfect voltage control of the entire cell membrane ("space clamp"), it is often assumed that currents measured at ...
Alon Poleg-Polsky, Jeffrey S Diamond
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Cortical PV and VIP interneurons similarly influence SST neuron output despite distinct unitary properties [PDF]
Communications BiologySomatostatin (SST) expressing cells are powerful inhibitors of excitatory pyramidal neurons. It has been shown that SST cells are targeted by other inhibitory interneurons, namely parvalbumin- (PV) and vasoactive intestinal polypeptide- (VIP) expressing ...
Felix Preuss +3 more
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Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neuronsin vitro [PDF]
Cellular and Molecular Neurobiology, 1987 The characteristics of long-duration inhibitory postsynaptic potentials (1-IPSPs) which are evoked in rat frontal neocortical neurons by local electrical stimulation were investigated with intracellular recordings from an in vitro slice preparation. Stimulation with suprathreshold intensities evoked 1-IPSPs with typical durations of 600-900 msec at ...
Howe, James R. +2 more
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Spike-timing dependent plasticity in inhibitory circuits [PDF]
Frontiers in Synaptic Neuroscience, 2010 Inhibitory circuits in the brain rely on GABA-releasing interneurons. For long, inhibitory circuits were considered weakly plastic in the face of patterns of neuronal activity that trigger long-term changes in the synapses between excitatory principal ...
Karri P Lamsa +2 more
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Melatonin suppresses abnormal hyperexcitability of hippocampal CA1 neurons in early-stage oxygen-glucose deprivation [PDF]
Frontiers in PharmacologyExcitotoxicity in the early stages of ischemia is a primary trigger of neuronal injury. Literature has indicated the potential neuroprotective effects of melatonin against ischemic hypoxic injury, but the direct electrophysiological mechanisms underlying
Yang Cui, Qi Wang, Chao Liu, Heng Zhou
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Visualization by high resolution immunoelectron microscopy of the transient receptor potential vanilloid-1 at inhibitory synapses of the mouse dentate gyrus. [PDF]
PLoS ONE, 2015 We have recently shown that the transient receptor potential vanilloid type 1 (TRPV1), a non-selective cation channel in the peripheral and central nervous system, is localized at postsynaptic sites of the excitatory perforant path synapses in the ...
Miren-Josune Canduela +7 more
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Spiking Neural P Systems with Membrane Potentials, Inhibitory Rules, and Anti-Spikes
Entropy, 2022 Spiking neural P systems (SN P systems for short) realize the high abstraction and simulation of the working mechanism of the human brain, and adopts spikes for information encoding and processing, which are regarded as one of the third-generation neural
Yuping Liu, Yuzhen Zhao
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Frontiers in Synaptic Neuroscience, 2022 Synaptic plasticity is a critical process that regulates neuronal activity by allowing neurons to adjust their synaptic strength in response to changes in activity.
Caitlyn A. Chapman +2 more
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Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord [PDF]
, 1975 The actions of glycine, GABA, α-alanine, β-alanine and taurine were studied by intracellular recordings from lumbar motoneurons of the isolated spinal cord of the frog.
Krumnikl, J. +9 more
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