Characteristics of long-duration inhibitory postsynaptic potentials in rat neocortical neuronsin vitro [PDF]
The characteristics of long-duration inhibitory postsynaptic potentials (1-IPSPs) which are evoked in rat frontal neocortical neurons by local electrical stimulation were investigated with intracellular recordings from an in vitro slice preparation. Stimulation with suprathreshold intensities evoked 1-IPSPs with typical durations of 600-900 msec at ...
James R. Howe +2 more
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Tetanus-induced potentiation of inhibitory postsynaptic potentials in hippooampal CA1 neurons
In the present study, tetanus-induced potentiation of inhibitory postsynaptic potentials (IPSPs), previously described by our laboratory, was further investigated in guinea pig hippocampal CA1 neurons. Tetanic stimulation of the stratum radiatum induced a long-term potentiation of the excitatory postsynaptic potential and a potentiation of the γ ...
Z, Xie +3 more
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Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation [PDF]
Gephyrin is a key scaffold protein mediating the anchoring of GABAA receptors at inhibitory synapses. Here, we exploited superresolution techniques combined with proximity-based clustering analysis and model simulations to investigate the single-molecule gephyrin reorganization during plasticity of inhibitory synapses in mouse hippocampal cultured ...
Pennacchietti, Francesca +10 more
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Effect of standing posture on inhibitory postsynaptic potentials in gastrocnemius motoneurons [PDF]
This study examined the task dependence of sensory inputs on motoneuron excitability by comparing the inhibitory postsynaptic potential (IPSP) evoked by stimulation of the sural nerve between a standing postural task (Free Standing) and a comparable voluntary isometric contraction performed in a supine position (Lying Supine).
S. Jayne Garland +3 more
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The pathway for the slow inhibitory postsynaptic potential in bullfrog sympathetic ganglia
Intracellular and sucrose gap recording techniques were used to examine synaptically evoked potentials and the response of neurons in bullfrog paravertebral sympathetic ganglia to muscarinic agonists. These neurons were defined as either B or C cells on the basis of the conduction velocity of antidromically evoked action potentials.
P A, Smith, F F, Weight
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Dendritic amplification of inhibitory postsynaptic potentials in a model Purkinje cell [PDF]
AbstractIn neurons with large dendritic arbors, the postsynaptic potentials interact in a complex manner with active and passive membrane properties, causing not easily predictable transformations during the propagation from synapse to soma. Previous theoretical and experimental studies in both cerebellar Purkinje cells and neocortical pyramidal ...
Sergio M. G. Solinas +2 more
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Modulatory effects of adenosine on inhibitory postsynaptic potentials in the lateral amygdala of the rat [PDF]
Adenosine is a depressant in the central nervous system with pre‐ and postsynaptic effects. In the present study, intracellular recording techniques were applied to investigate the modulatory effects of adenosine on projection neurons in the lateral rat amygdala (LA), maintained as slices in vitro. Adenosine reversibly reduced the amplitude of a fast
Thomas Heinbockel, Hans‐Christian Pape
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Effects of Methylphenidate on the Inhibitory Postsynaptic Potential in Rat Locus Coeruleus Neurons.
Effects of methylphenidate (MPH), an agent used clinically for the treatment of children presenting the attention-deficit/hyperactivity disorder (AD/HD), on synaptic transmission in the rat locus coeruleus (LC) were examined by intracellular recording methods.
Takashi Kuwahata +3 more
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Effects of milnacipran (MIL), a serotonin and noradrenaline reuptake inhibitor (SNRI), on synaptic transmission were examined in the rat locus coeruleus (LC). Bath-application of MIL produced a hyperpolarization associated with a decrease in input resistance of LC neurons.
Takashi Kuwahata +3 more
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Excitatory postsynaptic potentials in rat neocortical neurons in vitro. III. Effects of a quinoxalinedione non-NMDA receptor antagonist [PDF]
1. Intracellular microelectrodes were used to obtain recordings from neurons in layer II/III of rat frontal cortex. A bipolar electrode positioned in layer IV of the neocortex was used to evoke postsynaptic potentials.
J. J. Hablitz +3 more
core +2 more sources

