Results 21 to 30 of about 9,333,976 (340)

EPSPs in rat neocortical neurons in vitro. I. Electrophysiological evidence for two distinct EPSPs [PDF]

open access: yes, 1989
1. To investigate excitatory postsynaptic potentials (EPSPs), intracellular recordings were performed in layer II/III neurons of the rat medial frontal cortex.
Sutor, Bernd, Hablitz, John H.
core   +2 more sources

Inhibitory postsynaptic actions of taurine, GABA and other amino acids on motoneurons of the isolated frog spinal cord [PDF]

open access: yes, 1975
The actions of glycine, GABA, α-alanine, β-alanine and taurine were studied by intracellular recordings from lumbar motoneurons of the isolated spinal cord of the frog.
Krumnikl, J.   +9 more
core   +1 more source

Efavirenz restored NMDA receptor dysfunction and inhibited epileptic seizures in GluN2A/Grin2a mutant mice

open access: yesFrontiers in Neuroscience, 2023
IntroductionN-methyl-D-aspartate receptor (NMDAR) is one of the main receptor of the excitatory neurotransmitter glutamate in the brain, which is the key determinant of the excitatory/inhibitory balance of neural network.
Teng Zhao   +7 more
doaj   +1 more source

Nitric oxide signalling modulates synaptic inhibition in the superior paraolivary nucleus (SPN) via cGMP-dependent suppression of KCC2

open access: yesFrontiers in Neural Circuits, 2014
Glycinergic inhibition plays a central role in the auditory brainstem circuitries involved in sound localization and in the encoding of temporal action potential firing patterns.
Lina eYassin   +6 more
doaj   +1 more source

Phenomenological incorporation of nonlinear dendritic integration using integrate-and-fire neuronal frameworks. [PDF]

open access: yesPLoS ONE, 2013
It has been discovered recently in experiments that the dendritic integration of excitatory glutamatergic inputs and inhibitory GABAergic inputs in hippocampus CA1 pyramidal neurons obeys a simple arithmetic rule as V(S)(Exp) ≈ V(E)(Exp) + V(I)(Exp) + kV(
Douglas Zhou   +3 more
doaj   +1 more source

Imbalance of Excitation and Inhibition at Threshold Level In the Auditory Cortex

open access: yesFrontiers in Neural Circuits, 2015
The interplay of cortical excitation and inhibition is a fundamental feature of cortical information processing. Excitation and inhibition in single cortical neurons are balanced in their response to optimal sensory stimulation due to thalamocortical ...
Yan eZhao   +6 more
doaj   +1 more source

Functional maps of neocortical local circuitry

open access: yesFrontiers in Neuroscience, 2007
This review aims to summarize data obtained with different techniques to provide a functional map of the local circuit connections made by neocortical neurones, a reference for those interested in cortical circuitry and the numerical information required
Alex M Thomson, Christophe Lamy
doaj   +1 more source

Diurnal rhythms in neurexins transcripts and inhibitory/excitatory synapse scaffold proteins in the biological clock [PDF]

open access: yes, 2012
The neurexin genes (NRXN1/2/3) encode two families (α and β) of highly polymorphic presynaptic proteins that are involved in excitatory/inhibitory synaptic balance.
Hendricks, Michael   +15 more
core   +2 more sources

NMDA Currents Modulate the Synaptic Input–Output Functions of Neurons in the Dorsal Nucleus of the Lateral Lemniscus in Mongolian Gerbils [PDF]

open access: yes, 2011
Neurons in the dorsal nucleus of the lateral lemniscus (DNLL) receive excitatory and inhibitory inputs from the superior olivary complex (SOC) and convey GABAergic inhibition to the contralateral DNLL and the inferior colliculi.
Grothe, Benedikt   +3 more
core   +1 more source

Changes in synaptic transmission of substantia gelatinosa neurons after spinal cord hemisection revealed by analysis using in vivo patch-clamp recording

open access: yesMolecular Pain, 2016
Background After spinal cord injury, central neuropathic pain develops in the majority of spinal cord injury patients. Spinal hemisection in rats, which has been developed as an animal model of spinal cord injury in humans, results in hyperexcitation of ...
Yuji Kozuka MD   +6 more
doaj   +1 more source

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