Results 31 to 40 of about 71,654 (304)

EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs [PDF]

, 1989
1. Intracellular recordings were obtained from neurons in layer II/III of rat frontal cortex. Single-electrode current- and voltage-clamp techniques were employed to compare the sensitivity of excitatory postsynaptic potentials (EPSPs) and ...
J. J. Hablitz, Sutor, Bernd, Hablitz, John H., B. Sutor   +3 more
core   +1 more source

Interplay between low threshold voltage-gated K+ channels and synaptic inhibition in neurons of the chicken nucleus laminaris along its frequency axis

Frontiers in Neural Circuits, 2014
Central auditory neurons that localize sound in horizontal space have specialized intrinsic and synaptic cellular mechanisms to tightly control the threshold and timing for action potential generation.
William eHamlet, William eHamlet, Yu-Wei eLiu, Zhengquang eTang, Yong eLu, Yong eLu   +5 more
doaj   +1 more source

Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats

Neurobiology of Disease, 2022
Aberrant glucocorticoid signaling via glucocorticoid receptors (GR) plays a critical role in alcohol use disorder (AUD). Acute alcohol withdrawal and protracted abstinence in dependent rats are associated with increased GR signaling and changes in GR ...
Sophia Khom, Larry Rodriguez, Pauravi Gandhi, Dean Kirson, Michal Bajo, Christopher S. Oleata, Leandro F. Vendruscolo, Barbara J. Mason, Marisa Roberto   +8 more
doaj   +1 more source

Synaptic transfer of dynamic motion information between identified neurons in the visual system of the blowfly [PDF]

, 2003
Warzecha A-K, Kurtz R, Egelhaaf M. Synaptic transfer of dynamic motion information between identified neurons in the visual system of the blowfly. Neuroscience.
Egelhaaf, Martin ; https://orcid.org/, Kurtz, Rafael, Warzecha, Anne-Kathrin   +2 more
core   +2 more sources

Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex

Molecular Pain, 2018
Background Chronic pain is a persistent unpleasant sensation that produces pathological synaptic plasticity in the central nervous system. Both human imaging study and animal studies consistently demonstrate that the anterior cingulate cortex is a ...
Kohei Koga, Shuji Shimoyama, Akihiro Yamada, Tomonori Furukawa, Yoshikazu Nikaido, Hidemasa Furue, Kazuhiko Nakamura, Shinya Ueno   +7 more
doaj   +1 more source

Brain injury impairs working memory and prefrontal circuit function

Frontiers in Neurology, 2015
More than 2.5 million Americans suffer a traumatic brain injury (TBI) each year. Even mild to moderate traumatic brain injury causes long-lasting neurological effects.
Colin James Smith, Colin James Smith, Guoxiang eXiong, Jaclynn eElkind, Brendan James Putnam, Akiva eCohen   +5 more
doaj   +1 more source

Nucleus Reuniens Afferents in Hippocampus Modulate CA1 Network Function via Monosynaptic Excitation and Polysynaptic Inhibition

Frontiers in Cellular Neuroscience, 2021
The thalamic midline nucleus reuniens modulates hippocampal CA1 and subiculum function via dense projections to the stratum lacunosum-moleculare (SLM). Previously, anatomical data has shown that reuniens inputs in the SLM form synapses with dendrites of ...
Priyodarshan Goswamee, Elizabeth Leggett, A. Rory McQuiston   +2 more
doaj   +1 more source

Non-Hebbian Long-Term Potentiation of Inhibitory Synapses in the Thalamus [PDF]

, 2013
The thalamus integrates and transmits sensory information to the neocortex. The activity of thalamocortical relay (TC) cells is modulated by specific inhibitory circuits.
Nevian, Thomas, Sieber, Andrea Rahel, Sieber, Andrea, Min, Rogier   +3 more
core   +1 more source

Fast and slow voltage-dependent dynamics of magnesium block in the NMDA receptor: the asymmetric trapping block model [PDF]

, 2004
The NMDA receptor (NMDAR) produces a long-lasting component of the glutamatergic EPSC in mammalian central neurons. The current through NMDARs is voltage dependent as a result of block by extracellular magnesium, which has recently been shown to give ...
Vargas-Caballero, Mariana, Robinson, Hugh P.C.   +1 more
core   +1 more source

GluClR-mediated inhibitory postsynaptic currents reveal targets for ivermectin and potential mechanisms of ivermectin resistance.

PLoS Pathogens, 2019
Glutamate-gated chloride channel receptors (GluClRs) mediate inhibitory neurotransmission at invertebrate synapses and are primary targets of parasites that impact drastically on agriculture and human health.
Mohammed Atif, Jennifer J Smith, Argel Estrada-Mondragon, Xue Xiao, Angela A Salim, Robert J Capon, Joseph W Lynch, Angelo Keramidas   +7 more
doaj   +1 more source