Results 41 to 50 of about 9,333,976 (340)

EPSPs in rat neocortical neurons in vitro. II. Involvement of N-methyl-D-aspartate receptors in the generation of EPSPs [PDF]

, 1989
1. Intracellular recordings were obtained from neurons in layer II/III of rat frontal cortex. Single-electrode current- and voltage-clamp techniques were employed to compare the sensitivity of excitatory postsynaptic potentials (EPSPs) and ...
J. J. Hablitz, Sutor, Bernd, Hablitz, John H., B. Sutor   +3 more
core   +2 more sources

Interplay between low threshold voltage-gated K+ channels and synaptic inhibition in neurons of the chicken nucleus laminaris along its frequency axis

Frontiers in Neural Circuits, 2014
Central auditory neurons that localize sound in horizontal space have specialized intrinsic and synaptic cellular mechanisms to tightly control the threshold and timing for action potential generation.
William eHamlet, William eHamlet, Yu-Wei eLiu, Zhengquang eTang, Yong eLu, Yong eLu   +5 more
doaj   +1 more source

Alcohol dependence and withdrawal increase sensitivity of central amygdalar GABAergic synapses to the glucocorticoid receptor antagonist mifepristone in male rats

Neurobiology of Disease, 2022
Aberrant glucocorticoid signaling via glucocorticoid receptors (GR) plays a critical role in alcohol use disorder (AUD). Acute alcohol withdrawal and protracted abstinence in dependent rats are associated with increased GR signaling and changes in GR ...
Sophia Khom, Larry Rodriguez, Pauravi Gandhi, Dean Kirson, Michal Bajo, Christopher S. Oleata, Leandro F. Vendruscolo, Barbara J. Mason, Marisa Roberto   +8 more
doaj   +1 more source

Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex

Molecular Pain, 2018
Background Chronic pain is a persistent unpleasant sensation that produces pathological synaptic plasticity in the central nervous system. Both human imaging study and animal studies consistently demonstrate that the anterior cingulate cortex is a ...
Kohei Koga, Shuji Shimoyama, Akihiro Yamada, Tomonori Furukawa, Yoshikazu Nikaido, Hidemasa Furue, Kazuhiko Nakamura, Shinya Ueno   +7 more
doaj   +1 more source

Brain injury impairs working memory and prefrontal circuit function

Frontiers in Neurology, 2015
More than 2.5 million Americans suffer a traumatic brain injury (TBI) each year. Even mild to moderate traumatic brain injury causes long-lasting neurological effects.
Colin James Smith, Colin James Smith, Guoxiang eXiong, Jaclynn eElkind, Brendan James Putnam, Akiva eCohen   +5 more
doaj   +1 more source

Nucleus Reuniens Afferents in Hippocampus Modulate CA1 Network Function via Monosynaptic Excitation and Polysynaptic Inhibition

Frontiers in Cellular Neuroscience, 2021
The thalamic midline nucleus reuniens modulates hippocampal CA1 and subiculum function via dense projections to the stratum lacunosum-moleculare (SLM). Previously, anatomical data has shown that reuniens inputs in the SLM form synapses with dendrites of ...
Priyodarshan Goswamee, Elizabeth Leggett, A. Rory McQuiston   +2 more
doaj   +1 more source

Dynamic matching of the excitatory and inhibitory postsynaptic LTD/LTP thresholds and networks response to input perturbations.

, 2022
A. Postsynaptic LTD/LTP thresholds and shift dynamically depending on the recent postsynaptic rate νE. For lower postsynaptic rate than the excitatory postsynaptic LTD/LTP threshold (), decreases, and for , increases.
Julijana Gjorgjieva (255641), Christoph Miehl (8816756)   +1 more
core   +1 more source

Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs [PDF]

, 2003
Kretzberg J, Sejnowski T, Warzecha A-K, Egelhaaf M. Variability of postsynaptic responses depends non-linearly on the number of synaptic inputs. Neurocomputing.
Egelhaaf, Martin ; https://orcid.org/, Sejnowski, Terrence, Warzecha, Anne-Kathrin, Kretzberg, Jutta   +3 more
core   +1 more source

Fast and slow inhibitory postsynaptic potentials in the piriform cortex neurons.

Proceedings of the Japan Academy, Series B, 1978
Kensaku Mori, Masahiko Satou, Sadayuki F. Takagi   +2 more
openalex   +3 more sources

Molecular investigation of ergot alkaloid ergotamine's modulatory effects on glycine receptors expressed in Xenopus oocytes

Computational and Structural Biotechnology Journal
The relationship between oxidative stress and glycine receptors is complex, involving multiple mechanisms through which reactive oxygen species can modify glycine receptor function. Understanding these interactions is essential for developing therapeutic
Sanung Eom, Minsu Pyeon, Myungmi Moon, Jeongyeon Yun, Jaehui Yang, Jihwon Yun, Hye Duck Yeom, Mee-Hyun Lee, Gihyun Lee, Junho H. Lee   +9 more
doaj   +1 more source