Results 41 to 50 of about 71,654 (304)
Computational and Structural Biotechnology JournalThe relationship between oxidative stress and glycine receptors is complex, involving multiple mechanisms through which reactive oxygen species can modify glycine receptor function. Understanding these interactions is essential for developing therapeutic
Sanung Eom +9 more
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Cells, 2018 During strong parallel fiber stimulation, glutamate released at parallel fiber-Purkinje cell synapses activates type-1 metabotropic glutamate receptor (mGluR1) to trigger a slow excitatory postsynaptic current (sEPSC) in cerebellar Purkinje neurons.
Jinbin Tian, Michael X. Zhu
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Electrolyte Gated Oxide Pseudodiode for Inhibitory Synapse Applications [PDF]
, 2018 Recently, synaptic electronics are attracting increasing attention in neuromorphic engineering. Here, inhibitory synapses are proposed based on nanogranular phosphorous silicate glass gated indium tin oxide transistors operated in pseudodiode mode ...
Fei Yu +15 more
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The energy demand of fast neuronal network oscillations: insights from brain slice preparations
Frontiers in Pharmacology, 2012 Fast neuronal network oscillations in the gamma range (30-100 Hz) in the cerebral cortex have been implicated in higher cognitive functions such as sensual perception, working memory, and, perhaps, consciousness. However, little is known about the energy
Oliver eKann
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Inhibitory Postsynaptic Potentials Carry Synchronized Frequency Information in Active Cortical Networks [PDF]
, 2005 SummaryTemporal precision in spike timing is important in cortical function, interactions, and plasticity. We found that, during periods of recurrent network activity (UP states), cortical pyramidal cells in vivo and in vitro receive strong barrages of ...
McCormick, David A. +5 more
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Journal of Biomedical Science, 2017 Alteration in the excitatory/inhibitory neuronal balance is believed to be the underlying mechanism of epileptogenesis. Based on this theory, GABAergic interneurons are regarded as the primary inhibitory neurons, whose failure of action permits ...
Hui Ye, Stephanie Kaszuba
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Frontiers in Neuroscience, 2020 Signaling from the synapse to nucleus is mediated by the integration and propagation of both membrane potential changes (postsynaptic potentials) and intracellular second messenger cascades.
Jian Fu +3 more
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Progressive Parkinsonism in PPP2R5D‐Related Neurodevelopmental Disorder
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT PPP2R5D‐related neurodevelopmental disorder (Houge–Janssens syndrome type 1) is a rare autosomal dominant condition characterized by macrocephaly, intellectual disability, and epilepsy. Progressive parkinsonism is an emerging adult phenotype that neurologists should be aware of since timely genetic diagnosis opens the door to disease‐modifying
Katerina Bernardi +6 more
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Synaptic integration mechanisms. Theoretical and experimental investigation of temporal postsynaptic interactions between excitatory and inhibitory inputs [PDF]
, 1983 The effect of temporal activation of two closely adjacent synaptic inputs upon the postsynaptic output (voltage amplitude and time integral) is analyzed theoretically and experimentally. It is shown that (a) under certain conditions, maximal nonlinearity
Segev, I., Parnas, I.
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Advanced Functional Materials, EarlyView.In MOCVD MoS2 memristors, a current compliance‐regulated Ag filament mechanism is revealed. The filament ruptures spontaneously during volatile switching, while subsequent growth proceeds vertically through the MoS2 layers and then laterally along the van der Waals gaps during nonvolatile switching.
Yuan Fa +19 more
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