Results 61 to 70 of about 107,392 (304)

Melatonin Modulates the GABAergic Response in Cultured Rat Hippocampal Neurons

Journal of Pharmacological Sciences, 2012
In the present study, we investigated the effect of melatonin on the GABA-induced current (IGABA) and GABAergic miniature inhibitory postsynaptic currents (mIPSCs) in cultured rat hippocampal neurons using the whole-cell patch-clamp technique.
Xin-Ping Cheng, Hao Sun, Zeng-You Ye, Jiang-Ning Zhou   +3 more
doaj   +1 more source

Associative properties of structural plasticity based on firing rate homeostasis in recurrent neuronal networks

, 2018
Correlation-based Hebbian plasticity is thought to shape neuronal connectivity during development and learning, whereas homeostatic plasticity would stabilize network activity.
Gallinaro, Júlia V, Rotter, Stefan
core   +2 more sources

Presynaptic M1 muscarinic cholinoceptors mediate inhibition of excitatory synaptic transmission in the hippocampus in vitro [PDF]

, 1990
The effects of the cholinoceptor agonist, carbachol (CCh), were examined in the rat hippocampal slice preparation. Intracellular recordings from CA1 pyramidal neurones revealed that CCh (1–3 μM) inhibited excitatory postsynaptic responses evoked by ...
Sheridan, Robert D., Sutor, Bernd
core   +1 more source

Bioinspired Adaptive Sensors: A Review on Current Developments in Theory and Application

Advanced Materials, EarlyView.
This review comprehensively summarizes the recent progress in the design and fabrication of sensory‐adaptation‐inspired devices and highlights their valuable applications in electronic skin, wearable electronics, and machine vision. The existing challenges and future directions are addressed in aspects such as device performance optimization ...
Guodong Gong, You Zhou, Qingxiu Li, Wenyu Zhao, Sunyingyue Geng, Hangfei Li, Yan‐Bing Leng, Shirui Zhu, Guanglong Ding, Yongbiao Zhai, Ziyu Lv, Ye Zhou, Su‐Ting Han   +12 more
wiley   +1 more source

Photo‐Rewritable Ambipolar Organic Electrochemical Synapses with Bidirectional Optical Plasticity for Adaptive Vision in Aqueous Environments

Advanced Materials, EarlyView.
Photo‐rewritable ambipolar organic synapses operating in aqueous environments at low voltage (≤0.4 V) demonstrate bidirectional optical plasticity through photon‐modulated electrochemical doping. The bulk heterojunction device enables both excitatory and inhibitory responses with extended retention time (>130 min).
Xiaoqian Su, Xihu Wu, He Wang, Wenzhe Lu, Bing Xue, Jinli Tang, Zhangshanhao Li, Kejing Ren, Qiang He, Junyu Li, Lan Yin, Yuxin Liu, Shiming Zhang, Ting Lei, Changsheng Wu   +14 more
wiley   +1 more source

The effect of heterogeneity on decorrelation mechanisms in spiking neural networks: a neuromorphic-hardware study [PDF]

, 2014
High-level brain function such as memory, classification or reasoning can be realized by means of recurrent networks of simplified model neurons. Analog neuromorphic hardware constitutes a fast and energy efficient substrate for the implementation of ...
Diesmann, Markus, Grübl, Andreas, Jordan, Jakob, Meier, Karlheinz, Pfeil, Thomas, Schemmel, Johannes, Tetzlaff, Tom   +6 more
core   +5 more sources

Self‐Powered Flexible Triboelectric‐Gated Ion‐Gel Transistor for Neuromorphic Tactile Sensing and Human Activity Recognition

Advanced Materials, EarlyView.
A fully flexible ion‐gel‐gated graphene‐channel transistor driven by a triboelectric nanogenerator enables self‐powered tactile sensing and synaptic learning. Mimicking spike‐rate‐dependent plasticity, the device exhibits frequency‐selective potentiation and depression, supporting rate‐coded neuromorphic computation even under flex.
Hanseong Cho, Seoyeon Park, Youngmin Lee, Sejoon Lee   +3 more
wiley   +1 more source

Patch-Clamp Analysis of the Antinociceptive Actions of TRPA1 Activation in the Spinal Dorsal Horn

Molecular Pain, 2015
Background Transient receptor potential (TRP) channels are nonselective cation channels expressed in a variety of sensory structures, and are important molecular mediators of thermal, mechanical, cellular and chemical signals.
Manabu Yamanaka, Wataru Taniguchi, Naoko Nishio, Hiroshi Hashizume, Hiroshi Yamada, Munehito Yoshida, Terumasa Nakatsuka   +6 more
doaj   +1 more source

Depolarizing effect of neocortical chandelier neurons

Frontiers in Neural Circuits, 2009
Chandelier (or axo-axonic) cells are one of the most distinctive types of GABAergic interneurons in the cortex. Although they have traditionally been considered inhibitory neurons, data from rat and human neocortical preparations suggest that chandelier ...
Alan Woodruff, Qing Xu, Stewart A Anderson, Rafael Yuste   +3 more
doaj   +1 more source

A DLG2 deficiency in mice leads to reduced sociability and increased repetitive behavior accompanied by aberrant synaptic transmission in the dorsal striatum

Molecular Autism, 2020
Background DLG2, also known as postsynaptic density protein-93 (PSD-93) or chapsyn-110, is an excitatory postsynaptic scaffolding protein that interacts with synaptic surface receptors and signaling molecules.
Taesun Yoo, Sun-Gyun Kim, Soo Hyun Yang, Hyun Kim, Eunjoon Kim, Soo Young Kim   +5 more
doaj   +1 more source