Results 61 to 70 of about 8,886,109 (303)

Modulatory effects of adenosine on inhibitory postsynaptic potentials in the lateral amygdala of the rat [PDF]

British Journal of Pharmacology, 1999
Adenosine is a depressant in the central nervous system with pre‐ and postsynaptic effects. In the present study, intracellular recording techniques were applied to investigate the modulatory effects of adenosine on projection neurons in the lateral rat amygdala (LA), maintained as slices in vitro. Adenosine reversibly reduced the amplitude of a fast
T, Heinbockel, H C, Pape
openaire   +2 more sources

Parameters of networks used in simulations (exc: excitatory, inh: inhibitory, pop: population, amp: amplitude, CP: connection probability, PSP: postsynaptic potential, PSC: postsynaptic current, assem: assembly, conn: connections).

, 2018
Parameters of networks used in simulations (exc: excitatory, inh: inhibitory, pop: population, amp: amplitude, CP: connection probability, PSP: postsynaptic potential, PSC: postsynaptic current, assem: assembly, conn: connections).
Moritz Deger (306447), Wulfram Gerstner (129561), Hesam Setareh (5487965)   +2 more
core   +1 more source

Dynamic matching of the excitatory and inhibitory postsynaptic LTD/LTP thresholds.

, 2022
A. Plasticity curves of E-to-E (, blue) and I-to-E (, red) weights as a function of the postsynaptic rate νE with static, non-identical LTD/LTP thresholds (, ). B.
Julijana Gjorgjieva (255641), Christoph Miehl (8816756)   +1 more
core   +1 more source

Multimode Oxide‐Based Optoelectronic Memtransistor for In‐Sensor Vision Processing

Advanced Functional Materials, EarlyView.
A multimode optoelectronic memtransistor (OEMT) is demonstrated for vision explainable artificial intelligence (VXAI) hardware. By integrating optical sensing, electrical masking, and non‐volatile memory, the device enables key operations required for generating saliency information.
Min Gu Lee, Geunyoung Kim, Hwa Young Kim, Do Hoon Kim, Hanchan Song, Huisu Noh, Jungwan Noh, Seungwoo Lee, Sang‐Hee Ko Park, Himchan Cho, Kyung Min Kim   +10 more
wiley   +1 more source

Emerging Post‐CMOS Hardware Neurons for Brain‐Inspired Computing: Devices, Circuits, and System Integration

Advanced Functional Materials, EarlyView.
The physical realization of artificial neurons is a critical challenge for energy‐efficient neuromorphic computing. This review presents a comprehensive analysis of the evolution of artificial neuron implementations from conventional CMOS to emerging post‐CMOS technologies.
Kannan Udaya Mohanan, Hocheon Yoo, Benoît H. Lessard, Ioannis Kymissis, Chang‐Hyun Kim   +4 more
wiley   +1 more source

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Melatonin Modulates the GABAergic Response in Cultured Rat Hippocampal Neurons

Journal of Pharmacological Sciences, 2012
In the present study, we investigated the effect of melatonin on the GABA-induced current (IGABA) and GABAergic miniature inhibitory postsynaptic currents (mIPSCs) in cultured rat hippocampal neurons using the whole-cell patch-clamp technique.
Xin-Ping Cheng, Hao Sun, Zeng-You Ye, Jiang-Ning Zhou   +3 more
doaj   +1 more source

Effects of Methylphenidate on the Inhibitory Postsynaptic Potential in Rat Locus Coeruleus Neurons.

The Kurume Medical Journal, 2002
Effects of methylphenidate (MPH), an agent used clinically for the treatment of children presenting the attention-deficit/hyperactivity disorder (AD/HD), on synaptic transmission in the rat locus coeruleus (LC) were examined by intracellular recording methods.
KUWAHATA, TAKASHI, ISHIMATSU, MASARU, KIDANI, YURI, AKASU, TAKASHI   +3 more
openaire   +3 more sources

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source

GABA(B) receptor-mediated modulation of synaptic plasticity in the lateral amygdala [PDF]

, 2005
Fear conditioning, one of the most powerful and widely used methods to investigate the mechanisms of associative learning in animals, involves the pairing of an aversive stimulus such as a foot-shock (the unconditioned stimulus; US) with a neutral ...
Shaban, Hamdy
core   +1 more source