Results 201 to 210 of about 276,610 (317)

Nipocalimab‐aahu in generalised myasthenia gravis: A new Fc receptor‐targeted option for antibody‐positive patients

Ibrain, EarlyView.
Generalised myasthenia gravis (gMG) can be effectively treated with nipocalimab (Imaavy), a new FcRn inhibitor that selectively lowers harmful IgG levels without causing widespread immunosuppression. According to Phase 2/3 trials, nipocalimab exhibits favourable safety, broad age applicability (≥12 years), and sustained efficacy, setting it apart as a ...
Jawairya Muhammad Hussain, Anoosha Ashfaq, Azka Shahid, Fatima Mudassir   +3 more
wiley   +1 more source

Endophilin A1 facilitates organization of the GABAergic postsynaptic machinery to maintain excitation-inhibition balance. [PDF]

Elife
Chen X, Pan D, Liu JJ, Yang Y.
europepmc   +1 more source

Molecular imprinting for neurology: Materials, applications, and limitations

Ibrain, EarlyView.
Molecularly imprinted materials: diagnostic, therapeutic and research applications in neurology. Molecularly imprinted materials offer high specificity and affinity for target molecules in neurological applications. This review highlights their synthesis, characterisation, and use in diagnostics, research and therapeutics.
Xiaohan Ma, Yingqi Ma, Claudia Marino, Alessandro Poma   +3 more
wiley   +1 more source

Nicotinic Modulation of Fast-Spiking Neurons in Rat Somatosensory Cortex across Development. [PDF]

eNeuro
Haga CW, Koenig J, Cramer N, Chandra R, Keller A.   +4 more
europepmc   +1 more source

Microbiota‐gut‐brain axis multi‐organ chip construction and applications in drug evaluation

iMetaOmics, EarlyView.
Microbiota‐gut‐brain axis multiorgan chip and its applications in drug evaluation. The chip includes essential biological components such as gut microbiota, gut barrier, blood‐brain barrier (BBB), and brain. This integrated platform incorporates neural (blue), endocrine (yellow), immune (pink), and metabolic (green) pathways to investigate the impact ...
Yue Tang, Hewen Chen, Ziyue Zhao, Xuesong Kang, Wenxin Wang, Kun Dai, Yufei Guo, Axin Liang, Aiqin Luo, Zikai Hao   +9 more
wiley   +1 more source

Alpha-neurexins in health and disease. [PDF]

Front Mol Neurosci
Chofflet N, Wang M, Chofflet M, Takahashi H.   +3 more
europepmc   +1 more source

Optoelectronic synapses based on two‐dimensional transition metal dichalcogenides for neuromorphic applications

InfoScience, EarlyView.
This review first introduces the fundamental concepts of artificial synapses and synaptic plasticity, then discusses the device structures and operation mechanisms of optoelectronic synapses based on two‐dimensional transition metal dichalcogenides, highlights their applications in neuromorphic vision systems and computing, and concludes with key ...
Xiaona Sun, Yifan Hu, Chengbao Jiang, Shengxue Yang   +3 more
wiley   +1 more source

The synaptic architecture of layer 5 thick tufted excitatory neurons in mouse visual cortex. [PDF]

Nat Neurosci
Bodor AL, Schneider-Mizell CM, Zhang C, Elabbady L, Mallen A, Bergeson A, Brittain D, Buchanan J, Bumbarger DJ, Dalley R, Gamlin C, Joyce E, Kapner D, Kinn S, Mahalingam G, Seshamani S, Suckow S, Takeno M, Torres R, Yin W, Bae JA, Castro MA, Dorkenwald S, Halageri A, Jia Z, Jordan C, Kemnitz N, Lee K, Li K, Lu R, Macrina T, Mitchell E, Mondal SS, Mu S, Nehoran B, Popovych S, Silversmith W, Turner NL, Yu SC, Wong W, Wu J, Celii B, Campagnola L, Seeman SC, Jarsky T, Ren N, Arkhipov A, Reimer J, Seung HS, Reid RC, Collman F, da Costa NM.   +51 more
europepmc   +1 more source

Multi‐defect‐engineering in ZnO/GO heterostructures for optoelectronic synaptic devices with ultra‐high dynamic range and low energy consumption

InfoMat, EarlyView.
A multi‐defect‐engineered ZnO/GO flat‐band heterojunction enables a high‐dynamic‐range, low‐power optoelectronic synapse through enhanced photoresponse and reduced dark current. The device achieves a record 74.9 dB dynamic range and ultralow energy consumption of 23 fJ per spike at 1 mV.
Zhiyao Zheng, Baoshi Qiao, Zhanpo Han, Jie Qiu, Yifan Yao, Chang Shu, Yajing Liu, Huan Hu, Yang Xu, Bin Yu, Dongbo Wang, Ming Wang, Zheng Li   +12 more
wiley   +1 more source

Incremental self-organization of spatio-temporal spike pattern detection. [PDF]

Sci Rep
Dehghani Habibabadi M, Müller L, Pawelzik K.   +2 more
europepmc   +1 more source