Phosphorylation of GABA<sub>A</sub> receptor β<sub>3</sub> subunit at Ser<sup>408-409</sup> is essential for contextual learning at hippocampal CA1 synapses. [PDF]
Sakimoto Y +3 more
europepmc +1 more source
ABSTRACT Objective The complement component 5 inhibitor therapies (C5ITs) eculizumab and ravulizumab are approved for the treatment of generalized myasthenia gravis (gMG). We evaluated the real‐world effectiveness and safety of eculizumab and ravulizumab in patients with gMG with or without prior intravenous immunoglobulin (IVIg) or plasma exchange ...
Akiyuki Uzawa +2 more
wiley +1 more source
From Neurotransmission to Retinal Pathophysiology: Unraveling the Role of GABA Receptors in Retinal Disease Progression. [PDF]
Medina Arellano AE +5 more
europepmc +1 more source
Myeloid PD‐1 Regulates Astrocyte Development and Leads to Active Behaviours
During early neurodevelopment, PD‐1 ablation in myeloid cells influences myeloid proliferation/differentiation and causes sustained astrocyte overproliferation. PD‐1f/f; LysM‐Cre mice showed elevated astrocyte gene expression and behavioural changes.
Jie Qin +6 more
wiley +1 more source
Mechanisms of Different Motor Neurons in the Occurrence of Spasticity After Spinal Cord Injury: A Narrative Review. [PDF]
Gong H +6 more
europepmc +1 more source
Functional roles of synaptic inhibition in auditory temporal processing [PDF]
Pecka, Michael
core
Preferential superficial cortical layer activation during seizure propagation
Abstract Objective Focal cortical seizures travel long distances from the onset zone, but the long‐distance propagation pathways are uncertain. In vitro and in vivo imaging techniques have investigated the local spread of seizures but did not elucidate long‐distance spread. Furthermore, classical studies in slices suggested seizure spread locally along
Anastasia Brodovskaya +4 more
wiley +1 more source
Homeostatic synaptic plasticity of miniature excitatory postsynaptic currents in mouse cortical cultures requires neuronal <i>Rab3a</i>. [PDF]
Koesters AG, Rich MM, Engisch K.
europepmc +1 more source
Fast activity chirp patterns in focal seizures from patients and animal models
Abstract Time–frequency analysis of focal seizure electroencephalographic signals performed with depth electrodes in human temporal lobe structures has revealed the occurrence at onset of oscillations at approximately 30–100 Hz that feature a monotonic rapid decay in frequency content.
Maxime Lévesque +6 more
wiley +1 more source

