Results 91 to 100 of about 12,901 (262)
Modelling the Innate Immune System
, 2012 The Human Immune System (HIS) is a complex network composed of specialized cells, tissues, and organs that is responsible for protecting the organism against diseases caused by distinct pathogenic agents, such as viruses, bacteria and other parasites.
Pedro Augusto F. Rocha +5 more
openaire +4 more sources
Trauma: the role of the innate immune system.
World journal of emergency surgery : WJES, 2006 Immune dysfunction can provoke (multiple) organ failure in severely injured patients. This dysfunction manifests in two forms, which follow a biphasic pattern. During the first phase, in addition to the injury by trauma, organ damage is caused by the immune system during a systemic inflammatory response.
Ger T. Rijkers +3 more
openaire +4 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang +16 more
wiley +1 more source
Interactions between Innate Lymphoid Cells and Cells of the Innate and Adaptive Immune System
Frontiers in Immunology, 2017 Type 2 innate lymphoid cells (ILC2s) are a major source of cytokines, which are also produced by Th2 cells and several cell types of the innate immune system.
Cornelia Symowski, David Voehringer
doaj +1 more source
Innate Immunity: The Virtues of a Nonclonal System of Recognition [PDF]
, 1997 Ruslan Medzhitov, Charles A. Janeway
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Autosomal dominant progranulin (GRN) pathogenic variants are a genetic cause of frontotemporal lobar degeneration. Though clinical trials for GRN‐related therapies are underway, there is an unmet need for biomarkers that can predict symptom onset and track disease progression.
Taru M. Flagan +46 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han +9 more
wiley +1 more source
The innate immune system in cystic fibrosis lung disease [PDF]
, 1999 Robert Bals +2 more
openalex +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Managing long COVID in people with multiple sclerosis and related disorders (pwMSRD) is complex due to overlapping symptoms. To address evidence gaps, we evaluated long COVID susceptibility in pwMSRD versus controls and its associations with multi‐domain function and disability.
Chen Hu +15 more
wiley +1 more source
Analyse des „Innate”‐Immunsystems: Analysis of the „innate” immune system [PDF]
, 1999 Robert Smail Jack, Grit Wiegand
openalex +1 more source