Results 271 to 280 of about 1,265,061 (383)

Training vs. Tolerance: The Yin/Yang of the Innate Immune System. [PDF]

Biomedicines, 2023
Lajqi T, Köstlin-Gille N, Bauer R, Zarogiannis SG, Lajqi E, Ajeti V, Dietz S, Kranig SA, Rühle J, Demaj A, Hebel J, Bartosova M, Frommhold D, Hudalla H, Gille C.   +14 more
europepmc   +1 more source

Reinforced Polymer–Nanoparticle Hydrogels for Subcutaneous and Sustained Delivery of Trastuzumab

Advanced Healthcare Materials, EarlyView.
Biologic therapy development is rapidly accelerating, requiring extended delivery formulation strategies. Supramolecular hydrogels and electrostatic complexation create subcutaneous depots that release clinically relevant trastuzumab doses in a controlled manner through simple component mixing without chemical modifications.
Giovanni Bovone, Stéphane Bernhard, Guillaume Jacquot, Vincent Mittelheisser, Céline Mirjolet, Elia A. Guzzi, Lorenza Garau Paganella, Luca Liebi, Julien Draussin, Pedro Lopez Navarro, Elsa Barbé, Olivier Lefebvre, Jacky G. Goetz, Loic J. Charbonnière, Xavier Pivot, Sébastien Harlepp, Mark W. Tibbitt, Alexandre Detappe   +17 more
wiley   +1 more source

The Innate Immune System and the TRAIL-Bcl-XL Axis Mediate a Sex Bias in Lung Cancer and Confer a Therapeutic Vulnerability in Females. [PDF]

Cancer Res
May L, Hu B, Jerajani P, Jagdeesh A, Alhawiti O, Cai L, Semenova N, Guo C, Isbell M, Deng X, Faber AC, Pillappa R, Bandyopadhyay D, Wang XY, Neuwelt A, Koblinski J, Bos PD, Li H, Martin R, Landry JW.   +19 more
europepmc   +1 more source

Obesity Correlates with Chronic Inflammation of the Innate Immune System in Preeclampsia and HELLP Syndrome during Pregnancy. [PDF]

Biomedicines, 2023
Rimboeck J, Gruber M, Weigl M, Huber P, Lunz D, Petermichl W.   +5 more
europepmc   +1 more source

FPRs: linking innate immune system and fibrosis [PDF]

, 2015
MONTUORI, NUNZIA, ROSSI, FRANCESCA WANDA
core   +2 more sources

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

ORIGINAL ARTICLE: A Role for Mannose‐Binding Lectin, a Component of the Innate Immune System in Pre‐Eclampsia [PDF]

, 2008
Nándor Gábor Than, Roberto Romero, Offer Erez, Juan Pedro Kusanovic, Adi L. Tarca, Samuel S. Edwin, Jung‐Sun Kim, Sonia S. Hassan, Jimmy Espinoza, Pooja Mittal, Shali Mazaki‐Tovi, Lara Friel, Francesca Gotsch, Edi Vaisbuch, Natalia Camacho, Zoltán Papp   +15 more
openalex   +1 more source

Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy

Advanced Healthcare Materials, EarlyView.
The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq, Punnya Anil Kumar Jeeja, Sudip Kumar Dam, Sabya Sachi Das, Juan L. Vivero‐Escoto   +4 more
wiley   +1 more source

The role of genetic variants of NOD2/CARD15, a receptor of the innate immune system, in GvHD and complications following related and unrelated donor haematopoietic stem cell transplantation [PDF]

, 2008
Ernst Holler, Gerhard Rogler, Julia Brenmoehl, J. Hahn, Hildegard Greinix, Anne M. Dickinson, Gèrard Socié, Daniel Wolff, Jürgen Finke, Gottfried Fischer, Graham Jackson, Vanderson Rocha, Inken Hilgendorf, Günther Eißner, Jörg Marienhagen, Reinhard Andreesen   +15 more
openalex   +1 more source

OTULIN deficiency: focus on innate immune system impairment. [PDF]

Front Immunol
Dou B, Jiang G, Peng W, Liu C.
europepmc   +1 more source