Results 41 to 50 of about 934,612 (346)

The innate immune system 'puzzle' [PDF]

open access: yesNature Immunology, 2006
Detecting pathogen invasion and regulating homeostatic processes are two essential functions of myriad non-Toll-like innate immune proteins.
openaire   +2 more sources

The innate immune system in transplantation [PDF]

open access: yesSeminars in Immunology, 2011
The vertebrate innate immune system consists of inflammatory cells and soluble mediators that comprise the first line of defense against microbial infection and, importantly, trigger antigen-specific T and B cell responses that lead to lasting immunity.
Martin H, Oberbarnscheidt   +2 more
openaire   +2 more sources

Defective apoptotic cell clearance activates innate immune response to protect Caenorhabditis elegans against pathogenic bacteria

open access: yesVirulence, 2021
Appropriate clearance of dead cells generated by apoptosis is critical to the development of multicellular organisms and tissue homeostasis. In mammals, the removal of apoptotic cell is mediated by polarized monocyte/macrophage populations of the innate ...
Jinlong Wan   +4 more
doaj   +1 more source

Systems Biology and Innate Immunity

open access: yesJournal of Innate Immunity, 2013
The innate immune system is the first line of host defense against invading microorganisms and is essential for maintenance of host health. The innate immune response is largely mediated by soluble host factors—such as complement—and phagocytic leukocytes.
Scott D, Kobayashi, Frank R, Deleo
openaire   +3 more sources

Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia

open access: yesFrontiers in Cardiovascular Medicine, 2015
The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE).
Kelsey R Bounds   +2 more
doaj   +1 more source

Die Kämpfe únd schláchten—the struggles and battles of innate-like effector T lymphocytes with microbes

open access: yesFrontiers in Immunology, 2023
The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response.
Sebastian Joyce   +3 more
doaj   +1 more source

Integrative Genomics Reveals the Genetics and Evolution of the Honey Bee’s Social Immune System [PDF]

open access: yes, 2019
Social organisms combat pathogens through individual innate immune responses or through social immunity—behaviors among individuals that limit pathogen transmission within groups.
Currie, Rob   +12 more
core   +1 more source

Memory and Specificity in the Insect Immune System: Current Perspectives and Future Challenges

open access: yesFrontiers in Immunology, 2017
The immune response of a host to a pathogen is typically described as either innate or adaptive. The innate form of the immune response is conserved across all organisms, including insects.
Dustin Cooper, Ioannis Eleftherianos
doaj   +1 more source

Cell lineage tracing reveals the plasticity of the hemocyte lineages and of the hematopoietic compartments in Drosophila melanogaster [PDF]

open access: yes, 2010
Much of our knowledge on hematopoiesis, hematopoietic compartments, hematopoietic cell lineages and immunity has been derived from studies on the vertebrate immune system.
Brehélin   +33 more
core   +1 more source

Bone and the Innate Immune System [PDF]

open access: yesCurrent Osteoporosis Reports, 2014
The immune system and bone are intimately linked with significant physical and functionally related interactions. The innate immune system functions as an immediate response system to initiate protections against local challenges such as pathogens and cellular damage.
Charles, Julia F, Nakamura, Mary C
openaire   +4 more sources

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