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Virulence, 2021 Appropriate clearance of dead cells generated by apoptosis is critical to the development of multicellular organisms and tissue homeostasis. In mammals, the removal of apoptotic cell is mediated by polarized monocyte/macrophage populations of the innate ...
Jinlong Wan +4 more
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Frontiers in Immunology, 2019 The immune system is composed of two subsystems—the innate immune system and the adaptive immune system. The innate immune system is the first to respond to pathogens and does not retain memory of previous responses.
Nicole C. Smith +2 more
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The Chemokine System in Innate Immunity [PDF]
Cold Spring Harbor Perspectives in Biology, 2015 Chemokines are chemotactic cytokines that control the migration and positioning of immune cells in tissues and are critical for the function of the innate immune system. Chemokines control the release of innate immune cells from the bone marrow during homeostasis as well as in response to infection and inflammation.
Caroline L, Sokol, Andrew D, Luster
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The roles of extracellular vesicles in the immune system
Nature reviews. Immunology, 2022 Extracellular vesicles (EVs) are increasingly recognized as having ubiquitous roles in the immune system. This Review focuses on the progress made in the field in the past 5 years, including the roles of EVs in innate and adaptive immunity and their ...
E. Buzás
semanticscholar +1 more source
Frontiers in Immunology, 2023 The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response.
Sebastian Joyce +3 more
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Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis [PDF]
, 2004 Streptococcus uberis and Serratia marcescens are Gram-positive and Gram-negative bacteria, respectively, that induce clinical mastitis. Once initial host barrier systems have been breached by these pathogens, the innate immune system provides the next ...
Bannerman, Douglas D +5 more
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The innate immune system 'puzzle' [PDF]
Nature Immunology, 2006 Detecting pathogen invasion and regulating homeostatic processes are two essential functions of myriad non-Toll-like innate immune proteins.
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The innate immune system in transplantation [PDF]
Seminars in Immunology, 2011 The vertebrate innate immune system consists of inflammatory cells and soluble mediators that comprise the first line of defense against microbial infection and, importantly, trigger antigen-specific T and B cell responses that lead to lasting immunity.
Martin H, Oberbarnscheidt +2 more
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Regulation of short-chain fatty acids in the immune system
Frontiers in Immunology, 2023 A growing body of research suggests that short-chain fatty acids (SCFAs), metabolites produced by intestinal symbiotic bacteria that ferment dietary fibers (DFs), play a crucial role in the health status of symbiotes. SCFAs act on a variety of cell types
Xiao-feng Liu +9 more
semanticscholar +1 more source
Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia
Frontiers in Cardiovascular Medicine, 2015 The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE).
Kelsey R Bounds +2 more
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