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The innate immune system 'puzzle' [PDF]
Detecting pathogen invasion and regulating homeostatic processes are two essential functions of myriad non-Toll-like innate immune proteins.
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The innate immune system in transplantation [PDF]
The vertebrate innate immune system consists of inflammatory cells and soluble mediators that comprise the first line of defense against microbial infection and, importantly, trigger antigen-specific T and B cell responses that lead to lasting immunity.
Martin H, Oberbarnscheidt +2 more
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Appropriate clearance of dead cells generated by apoptosis is critical to the development of multicellular organisms and tissue homeostasis. In mammals, the removal of apoptotic cell is mediated by polarized monocyte/macrophage populations of the innate ...
Jinlong Wan +4 more
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Systems Biology and Innate Immunity
The innate immune system is the first line of host defense against invading microorganisms and is essential for maintenance of host health. The innate immune response is largely mediated by soluble host factors—such as complement—and phagocytic leukocytes.
Scott D, Kobayashi, Frank R, Deleo
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Four Pathways Involving Innate Immunity in the Pathogenesis of Preeclampsia
The maternal innate immune system plays an important role both in normal pregnancy as well as hypertensive disorders of pregnancy including preeclampsia (PE).
Kelsey R Bounds +2 more
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The large majority of lymphocytes belong to the adaptive immune system, which are made up of B2 B cells and the αβ T cells; these are the effectors in an adaptive immune response.
Sebastian Joyce +3 more
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Integrative Genomics Reveals the Genetics and Evolution of the Honey Bee’s Social Immune System [PDF]
Social organisms combat pathogens through individual innate immune responses or through social immunity—behaviors among individuals that limit pathogen transmission within groups.
Currie, Rob +12 more
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Memory and Specificity in the Insect Immune System: Current Perspectives and Future Challenges
The immune response of a host to a pathogen is typically described as either innate or adaptive. The innate form of the immune response is conserved across all organisms, including insects.
Dustin Cooper, Ioannis Eleftherianos
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Cell lineage tracing reveals the plasticity of the hemocyte lineages and of the hematopoietic compartments in Drosophila melanogaster [PDF]
Much of our knowledge on hematopoiesis, hematopoietic compartments, hematopoietic cell lineages and immunity has been derived from studies on the vertebrate immune system.
Brehélin +33 more
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Bone and the Innate Immune System [PDF]
The immune system and bone are intimately linked with significant physical and functionally related interactions. The innate immune system functions as an immediate response system to initiate protections against local challenges such as pathogens and cellular damage.
Charles, Julia F, Nakamura, Mary C
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