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Innate lymphoid cells (ILCs) are lymphoid cells that do not express rearranged receptors and have important effector and regulatory functions in innate immunity and tissue remodeling. ILCs are categorized into 3 groups based on their distinct patterns of
Hazenberg, Mette D., Spits, Hergen
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Editorial: Innate lymphoid cell development, migration, and function [PDF]
Jorge Henao-Mejía +5 more
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Autophagy is an essential cellular homeostasis pathway initiated by multiple stimuli ranging from nutrient deprivation to viral infection, playing a key role in human health and disease.
Manuela Giansanti +7 more
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Innate lymphoid cell recovery and occurrence of GvHD after hematopoietic stem cell transplantation
International audienceLymphocytes are essential for microbial immunity, tumor surveillance, and tissue homeostasis. However, the in vivo development and function of helper-like innate lymphoid cells (ILCs) in humans remain much less well understood than ...
Barlogis, Vincent +13 more
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Innate Lymphoid Cells in the Central Nervous System
Immune cells are present within the central nervous system and play important roles in neurological inflammation and disease. As relatively new described immune cell population, Innate Lymphoid Cells are now increasingly recognized within the central ...
Shuaiwei Wang, Serge A. van de Pavert
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Innate lymphoid cells in the airways [PDF]
The airways, similar to other mucosal surfaces, are continuously exposed to the outside environment and a barrage of antigens, allergens, and microorganisms. Of critical importance therefore is the ability to mount rapid and effective immune responses to control commensal and pathogenic microbes, while simultaneously limiting the extent of these ...
Jennifer A, Walker, Andrew, McKenzie
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Innate lymphoid cells and the skin [PDF]
Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung, skin and gut (Nature 464:1367-1371, 2010, Nat Rev Immunol 13: 145-149, 2013).
Salimi, Maryam, Ogg, Graham
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Natural killer cells and type 1 innate lymphoid cells in cancer
International audienceInnate lymphoid cells (ILCs) are a group of innate lymphocytes that do not express RAG-dependent rearranged antigen-specific cell surface receptors.
Vivier, Eric +5 more
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The evolution of innate lymphoid cells [PDF]
Innate lymphoid cells (ILCs) are the most recently discovered group of immune cells. Understanding their biology poses many challenges. We discuss here the current knowledge on the appearance of ILC subsets during evolution and propose how the connection between ILCs and T cells contributes to the robustness of immunity and hence to the fitness of the ...
Vivier, Eric +3 more
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Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy [PDF]
Helminth parasites such as the nematode Heligmosomoides polygyrus strongly inhibit T helper type 2 (Th2) allergy, as well as colitis and autoimmunity. Here, we show that the soluble excretory/secretory products of H.
McSorley, H. J.; id_orcid +15 more
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