Results 71 to 80 of about 128,560 (293)
Nature Communications, 2023 Tissue-resident macrophages are critical for tissue homeostasis and repair. We previously showed that dermis-resident macrophages produce CCL24 which mediates their interaction with IL-4+ eosinophils, required to maintain their M2-like properties in the ...
Sang Hun Lee +8 more
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Lymphoid microenvironments and innate lymphoid cells in the gut
Trends in Immunology, 2012 Gut-associated lymphoid tissue (GALT) is a sensor region for luminal content and plays an important role in lymphoid maturation, activation and differentiation. It comprises isolated and aggregated lymphoid follicles, cryptopatches (CPs) and tertiary lymphoid tissue. Innate lymphoid cells (ILCs) play a central role within GALT.
Pearson, C, Uhlig, H, Powrie, F
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A committed precursor to innate lymphoid cells [PDF]
Nature, 2014 Innate lymphoid cells (ILCs) specialize in the rapid secretion of polarized sets of cytokines and chemokines to combat infection and promote tissue repair at mucosal barriers. Their diversity and similarities with previously characterized natural killer (NK) cells and lymphoid tissue inducers (LTi) have prompted a provisional classification of all ...
Michael G, Constantinides +3 more
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FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
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Intrinsic Control of Surface Immune and Epithelial Homeostasis by Tissue-Resident Gut Stromal Cells
Frontiers in Immunology, 2019 The epithelial layer creates a chemical and physical barrier at the forefront of intestinal mucosa, and immune cells beneath the surface epithelium are poised to react to extrinsic factors, to maintain tissue homeostasis.
Yosuke Kurashima +16 more
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Cells, 2022 The journal retracts the article, “Rolot, M. and O’Sullivan, T. E. Living with Yourself: Innate lymphoid Cell Immunometabolism. Cells 2020, 9, 334” [...]
Marion Rolot, Timothy E. O’Sullivan
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Innate lymphoid cells in secondary lymphoid organs
Immunological Reviews, 2016 SummaryThe family of innate lymphoid cells (ILCs) has attracted attention in recent years as its members are important regulators of immunity, while they can also cause pathology. In both mouse and man, ILCs were initially discovered in developing lymph nodes as lymphoid tissue inducer (LTi) cells.
Bar-Ephraïm, JE, Mebius, Reina E.
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Innate Lymphoid Cells in Tumor Immunity [PDF]
Biomedicines, 2016 Innate lymphoid cells (ILCs) are a group of immune cells of the lymphoid lineage that do not possess antigen specificity. The group includes natural killer (NK) cells, lymphoid tissue inducer (LTi) cells and the recently identified ILC1s, ILC2s and ILC3s.
Jasper Van Beek +3 more
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Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
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Inhibition of autophagy enhances the antitumor efficacy of T/CAR T cell against neuroblastoma
Journal of Experimental & Clinical Cancer ResearchNeuroblastoma (NB) is the most common extracranial solid tumor in children characterized by poor immune infiltration and resistance to adaptive immunity, contributing to its limited response to immunotherapy.
Francesca De Mitri +19 more
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