Results 181 to 190 of about 911 (209)
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Transition of inner cell mass to embryonic stem cells: mechanisms, facts, and hypotheses

Cellular and Molecular Life Sciences, 2018
Embryonic stem cells (ESCs) are immortal stem cells that own multi-lineage differentiation potential. ESCs are commonly derived from the inner cell mass (ICM) of pre-implantation embryos. Due to their tremendous developmental capacity and unlimited self-renewal, ESCs have diverse biomedical applications.
Hassani, S.   +4 more
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Tetraploid Embryonic Stem Cells Contribute to the Inner Cell Mass of Mouse Blastocysts

Cloning and Stem Cells, 2005
The demonstration that mouse somatic cells can be reprogrammed following fusion with embryonic stem (ES) cells may provide an alternative to somatic cell nuclear transfer (therapeutic cloning) to generate autologous stem cells. In an attempt to produce cells with an increased pool of reprogramming factors, tetraploid ES cells were produced by ...
Pralong, D.   +6 more
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Energy metabolism of the inner cell mass and trophectoderm of the mouse blastocyst

Differentiation, 2006
Mammalian pre-implantation development culminates in the formation of the blastocyst consisting of two distinct cell lineages, approximately a third of the cells comprise the pluripotent inner cell mass (ICM) and the remainder the differentiated trophectoderm (TE).
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[Mechanics of inner cell mass formation].

Biologie aujourd'hui, 2018
During the very first days of mammalian development, the embryo forms a structure called the blastocyst. The blastocyst consists of two cell types: the trophectoderm (TE), which implants the embryo in the uterus and the inner cell mass (ICM), which gives rise to all cells of the mammalian body.
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Investigation of the determinative state of the mouse inner cell mass. I. Aggregation of isolated inner cell masses with morulae.

Journal of embryology and experimental morphology, 1975
Inner cell masses (ICMs) were dissected from 3 1/2- and 4 1/2-day blastocysts and cultured in contact with 2 1/2-day morulae. Blastocysts and morulae were homozygous for different electrophoretic variants of the enzyme glucose phosphate isomerase (GPI).
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A quantitative analysis of cell allocation to trophectoderm and inner cell mass in the mouse blastocyst

Developmental Biology, 1987
The allocation of cells to the trophectoderm and inner cell mass (ICM) in the mouse blastocyst has been examined by labelling early morulae (16-cell stage) with the short-term cell lineage marker yellow-green fluorescent latex (FL) microparticles. FL is endocytosed exclusively into the outside polar cell population and remains autonomous to the progeny
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Investigation of the determinative state of the mouse inner cell mass. II. The fate of isolated inner cell masses transferred to the oviduct.

Journal of embryology and experimental morphology, 1975
Inner cell masses (ICMs) were dissected from 3 1/2- and 4 1/2-day mouse blastocysts and inserted into empty zonae before transfer to the oviducts of pseudopregnant mice. The ICMs survived in the oviduct for at least 2 days with little evidence of reduction in cell number.
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Proliferation and differentiation of porcine inner cell mass and epiblast in vitro.

Biology of reproduction, 1997
The proliferation rate and differentiation state were investigated in porcine inner cell masses (ICMs) and epiblasts in vitro. ICMs isolated from early blastocysts (Day 7 of pregnancy) and epiblasts isolated from preelongated blastocysts (Day 11 of pregnancy) were cultured for up to 5 days in the presence of human leukemia inhibitory factor (hLIF ...
Wianny, F.   +2 more
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Inner Cell Mass Development

2018
Björn Oback, Zachariah L Mclean
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