Results 61 to 70 of about 851,496 (289)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Networked by design: can policy constraints support the development of capabilities for collaborative innovation? [PDF]

, 2013
While there has been some recent interest in the behavioural effects of policies in support of innovation networks, this research field is still relatively new.
Caloffi, A., Rossi, Federica, Russo, M.
core  

Development of Dynamic Capabilities for Automotive Industry Performance under Disruptive Innovation

Journal of Open Innovation: Technology, Market and Complexity, 2020
Dynamic capabilities are creating dramatic change for the industry around the world. Resource-Based View (RBV) theory and Operational capability theory are the basic capabilities of an organization under a normal changing environment.
Atichat Rotjanakorn, Pornrat Sadangharn, Khahan Na-Nan   +2 more
doaj   +1 more source

New business model of integration practices between TQM and SCM: the role of innovation capabilities [PDF]

Problems and Perspectives in Management, 2019
The concept of “total quality management (TQM)” is broadly used in business. Regardless of the fact that several studies have analyzed this topic, little research has been conducted on integrating total quality management and supply chain management (SCM)
Hana Arrfou
doaj   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

TECHNOLOGICAL COLLABORATION: BRIDGING THE INNOVATION GAP BETWEEN SMALL AND LARGE FIRMS [PDF]

This paper analyses technological collaboration as an input to the innovation processes of SMEs. Technological collaboration may be a useful mechanism to offset some of the weaknesses in SMEs’ resource endowments and bring their innovation capabilities ...
Lluis Santamaria, Maria Jesus Nieto
core   +3 more sources

CRM System: the Role of Dynamic Capabilities in creating Innovation Capability

BBR: Brazilian Business Review, 2018
Customer relationship management (CRM) is a topic discussed, mainly, by information systems and marketing management areas. Many organizations are already using CRM systems.
Cristiane Drebes Pedron, Winnie Ng Picoto, Miguel Colaco, Cintia Cristina Araújo   +3 more
doaj   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Modeling the significance of corporate social responsibility on green capabilities and sustainability performance

Heliyon
This study examines the complex interplay among corporate social responsibility (CSR), green dynamic capabilities, green innovation capabilities, and organizations' economic, environmental, and social performance in the current era of innovation and ...
Han Xiao, Abdullah Al Mamun, Mohammad Nurul Hassan Reza, Xiaofang Lin, Qing Yang   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source