Results 101 to 110 of about 69,045 (225)

Profiles of Streptococcus thermophilus MN‐ZLW‐002 nutrient requirements in controlled pH batch fermentations

MicrobiologyOpen, 2019
This study aimed to evaluate the profiles of Streptococcus thermophilus nutrient requirements to guide the design of media for high cell density culturing. The growth kinetics, physiological state, and nutrient requirement profiles of S.
Gefei Liu, Yali Qiao, Yanjiao Zhang, Cong Leng, Jiahui Sun, Hongyu Chen, Yan Zhang, Aili Li, Zhen Feng   +8 more
doaj   +1 more source

Narrative review of strategies for blood product shelf‐life extension

Transfusion, EarlyView.
Mike Akaraphanth, Jessica Oudakker, Matthew Paulson, Michael Adam Meledeo, Kristin M. Reddoch‐Cardenas, Lusha Xiang, Steven G. Schauer, Todd Getz   +7 more
wiley   +1 more source

Codon decoding by orthogonal tRNAs interrogates the in vivo preferences of unmodified adenosine in the wobble position

Frontiers in Genetics
The in vivo codon decoding preferences of tRNAs with an authentic adenosine residue at position 34 of the anticodon, the wobble position, are largely unexplored because very few unmodified A34 tRNA genes exist across the three domains of life.
Margaret A. Schmitt, Jillyn M. Tittle, John D. Fisk   +2 more
doaj   +1 more source

Prophylactic supplementation with Bifidobacterium infantis or its metabolite inosine attenuates cardiac ischemia/reperfusion injury

iMeta
Emerging evidence has demonstrated the profound impact of the gut microbiome on cardiovascular diseases through the production of diverse metabolites. Using an animal model of myocardial ischemia–reperfusion (I/R) injury, we found that the prophylactic ...
Hao Zhang, Jiawan Wang, Jianghua Shen, Siqi Chen, Hailong Yuan, Xuan Zhang, Xu Liu, Ying Yu, Xinran Li, Zeyu Gao, Yaohui Wang, Jun Wang, Moshi Song   +12 more
doaj   +1 more source

Inhibition of inosine metabolism of the gut microbiota decreases testosterone secretion in the testis

mSystems
Growing evidence indicates that gut microbiota is involved in the regulation of the host’s sex hormone levels, such as through interfering with the sex hormone metabolism in the intestine.
Lei Tang, Xizhong Yang, Mengting Zhou, Lingxin Feng, Cuijie Ji, Jie Liang, Bei Zhang, Ruowu Shen, Luoyang Wang   +8 more
doaj   +1 more source

Microbiota‐Derived Inosine Suppresses Systemic Autoimmunity via Restriction of B Cell Differentiation and Migration

Advanced Science
The role of gut microbiota dysbiosis in systemic lupus erythematosus (SLE) pathogenesis remains elusive. Here, it is shown that fecal microbiota transplantation (FMT) from healthy mice to lupus mice ameliorates lupus‐like symptoms.
Lingyu Gao, Yuhan Zhang, Zhi Hu, Shengwen Chen, Qiaolin Wang, Yong Zeng, Huiqi Yin, Junpeng Zhao, Yijing Zhan, Changxing Gao, Yue Xin, Bing Chen, Stijn van derVeen, Ming Zhao, Deyu Fang, Qianjin Lu   +15 more
doaj   +1 more source

Comparison of the radioprotective effects of copper chlorophyllin, riboxin, indralin, and the combined use of glutathione and ascorbic acid based on the physiological parameters in mice exposed to fractionated irradiation

Учёные записки Казанского университета: Серия Естественные науки
The radioprotective effects of copper chlorophyllin, riboxin, indralin, and the combined use of glutathione and ascorbic acid were compared in male ICR (CD-1) mice exposed to five daily irradiations at doses of 1.4 or 2.5 Gy, with all compounds ...
L. A. Romodin, A. A. Moskovskij, O. V. Nikitenko, T. M. Bychkova, O. V. Mikenin, D. A. Bocharov, E. D. Rodionova   +6 more
doaj   +1 more source

Inosine reverses multidrug resistance in Gram-negative bacteria carrying mobilized RND-type efflux pump gene cluster tmexCD-toprJ

mSystems
Antimicrobial resistance is rapidly increasing worldwide, highlighting the urgent need for pharmaceutical and nonpharmaceutical interventions to tackle different-to-treat bacterial infections.
Fulei Li, Tianqi Xu, Dan Fang, Zhiqiang Wang, Yuan Liu   +4 more
doaj   +1 more source

Preparation, Quality and Purine-lowering Activity of Functional Yak Yoghurt during Storage Period

Shipin gongye ke-ji
In order to develop a purine-reducing functional yak yoghurt, Lactobacillus paracasei 259 and commercial starter was used as the fermentation strain in this experiment.
Xindi YU, Jingya LIU, Xiumei REN, Lianhong CHEN   +3 more
doaj   +1 more source

Nerve repair with polylactic acid and inosine treatment enhance regeneration and improve functional recovery after sciatic nerve transection

Frontiers in Cellular Neuroscience
BackgroundFollowing transection, nerve repair using the polylactic acid (PLA) conduit is an effective option. In addition, inosine treatment has shown potential to promote nerve regeneration.
Fellipe Soares dos Santos Cardoso, Guilherme dos Santos Maria, Fernanda Marques Pestana, Ricardo Cardoso, Bruna dos Santos Ramalho, Bruna dos Santos Ramalho, Luiza dos Santos Heringer, Tiago Bastos Taboada, Ana Maria Blanco Martinez, Fernanda Martins de Almeida, Fernanda Martins de Almeida   +10 more
doaj   +1 more source