Results 111 to 120 of about 54,859 (243)
Microbial Mechanisms and Sensory Outcomes of Flavor Development in Fermented Plant‐Based Proteins
Sustainable Food Proteins, Volume 4, Issue 4, December 2026.Fermentation improves the flavor and consumer appeal of plant‐based proteins by reducing off‐flavors and generating desirable taste and aroma compounds. This review summarizes microbial mechanisms of flavor development, factors influencing sensory quality, and emerging opportunities in precision fermentation, flavoromics, and microbial engineering ...
Nancy D. Asen
wiley +1 more source
The degradation of inosine and guanosine by DM9218.
, 2014 (a) Control: inosine and guanosine solution without inoculation of bacteria (270 µL of the inosine and guanosine solution was incubated at 37°C for 60 min, after that 30 µL HClO4 was added, 20 µL of the mixture was analyzed by HPLC).
Dianbin Yang (625123) +5 more
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Molecular Oncology, Volume 20, Issue 11, Page 2936-2954, November 2026.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Inosine treatment increases the extent of NF200 immunoreactivity following spinal cord injury.
, 2015 (A) Representative photomicrographs of staining for the Aδ fiber marker NF200 (red) in bladder sections from SCI rats treated with vehicle or inosine or non-surgical controls are shown.
Debra Franck (284585) +11 more
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Cell Biochemistry and Function, Volume 44, Issue 11, November 2026.ABSTRACT Atherosclerosis is driven by coordinated changes in endothelial cells (ECs), macrophages, and vascular smooth muscle cells (VSMCs). Post‐translational modifications (PTMs), phosphorylation, acetylation, ubiquitination, SUMOylation, O‐GlcNAcylation, palmitoylation, ISGylation, and ADP‐ribosylation, integrate metabolic, inflammatory, and ...
Weiwei Jiang, Haiping Du
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XDH Inhibits the Progression of Colorectal Cancer via Regulating Ferritinophagy Signaling
Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.XDH inhibits the progression of CRC via mediating ferritinophagy and ferroptosis. Therefore, XDH/ferritinophagy may be a potential target for CRC. ABSTRACT Xanthine dehydrogenase (XDH) is involved in the progression of various cancer. This study aimed to investigate its potential in colorectal cancer (CRC). Gene expression was determined using RT‐qPCR,
Huiying Zhang +6 more
wiley +1 more source
Antiarrhythmic and arrhythmogenic action of inosine in experimental ventricular tachyarrhythmias
, 2009 Objective: To study the possible action of inosine on experimental ventricular tachyarrhythmias. Material and methods: We used 92 mongrel dogs weighing 13 kg-17 kg, anesthetized with 30 mg/kg sodium pentobarbital applied intravenously. Myocardial lesions
Chávez Domínguez,Rafael +4 more
core
Physiological Reports, Volume 14, Issue 21, November 2026.Gradual heat exposure (20°C–38°C) triggered immune, lung, and metabolic changes in mice, revealing systemic responses that may better model the biological effects of real‐world heatwaves. Abstract Heatwaves are an increasing public health concern, yet most animal studies use sudden extreme heat exposure that poorly reflects real‐world conditions.
Laura E. Dean +2 more
wiley +1 more source
The FASEB Journal, Volume 40, Issue 20, 31 October 2026.Endothelial Matrin‐3 suppresses cellular senescence and protects against atherosclerosis. Matrin‐3 deficiency induces endothelial senescence, mitochondrial dysfunction, and activation of p53‐, cell cycle‐, and senescence‐related pathways. In atherosclerosis‐prone mice, endothelial Matrin‐3 deletion promotes atherosclerotic lesion formation and disrupts
Xiao Cheng +5 more
wiley +1 more source
Effect of trolox, riboxin (inosine), and indralin on X-ray induced oxidative stress in A549 cells
Учёные записки Казанского университета: Серия Естественные наукиUsing dichlorofluorescein (DCF) fluorescence intensity, the oxidative stress in human lung adenocarcinoma A549 cells pretreated with trolox, riboxin (inosine), tartaric acid, and indralin was measured 2 h before, during, and 1 h after the X-ray radiation
L. A. Romodin
doaj +1 more source