Results 31 to 40 of about 66,823 (327)
Inosine as a Tool to Understand and Treat Central Nervous System Disorders: A Neglected Actor?
Frontiers in Neuroscience, 2021 Since the 1970s, when ATP was identified as a co-transmitter in sympathetic and parasympathetic nerves, it and its active metabolite adenosine have been considered relevant signaling molecules in biological and pathological processes in the central ...
F. P. Nascimento +4 more
semanticscholar +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 181-190, January 2023., 2023 Our project aims to reveal the cryoprotective effect of flammulina velutipes polysaccharide (FVP) on the quality characteristics in freeze‐thawed cultured large yellow croaker. The differences were compared with conventional commercial cryoprotectant in combination with muscle quality, body color, and flavor.
Yuzhuo Shi +5 more
wiley +1 more source
Cells, 2020 Human subcutaneous fibroblasts (HSCF) challenged with inflammatory mediators release huge amounts of ATP, which rapidly generates adenosine. Given the nucleoside’s putative relevance in wound healing, dermal fibrosis, and myofascial pain, we ...
Carina Herman-de-Sousa +9 more
doaj +1 more source
A purinergic call to arms from dying brown adipocytes
Cell Stress, 2022 Brown adipocytes react to temperature and nutritional challenges by ramping up their metabolism and generating heat. This adaptation to changes in the environment is crucial for defending organismal homeostasis, but is impaired in obesity and ...
Mohammed K. Hankir
doaj +1 more source
Inosine metabolism in the rat [PDF]
Biochemical Journal, 1982 1. Uptake and subsequent metabolism of purine and ribose moieties was monitored after intravenous administration of doubly labelled inosine. 2. More than 95% was cleared from the plasma within 5 min, and 99% within 20 min. 3. Approx. 50% of the 160 mumol total was rapidly incorporated into liver and kidney.
A R Fernando, J R Griffiths, R J Sharma
openaire +3 more sources
Journal of Advanced Biotechnology and Experimental Therapeutics, 2023 Purine Nucleoside Phosphorylase (PNP) is an enzyme involved in biosynthetic pathway of purine nucleosides. Purine nucleoside phosphorylase catalyzes the cleavage of the glycosidic bond of ribo- or deoxyribonucleosides to form the purine base and ...
Jaloliddin Abdurakhmanov +12 more
doaj +1 more source
New insights into the biological role of mammalian ADARs; the RNA editing proteins [PDF]
, 2015 The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA.
Arieti, Fabiana +4 more
core +2 more sources
Role of RNA modifications in carcinogenesis and carcinogen damage response
Molecular Carcinogenesis, Volume 62, Issue 1, Page 24-37, January 2023., 2023 Abstract The field of epitranscriptomics encompasses the study of post‐transcriptional RNA modifications and their regulatory enzymes. Among the numerous RNA modifications, N6‐methyladenosine (m6A) has been identified as the most common internal modification of messenger RNA (mRNA).
Michelle Verghese +2 more
wiley +1 more source
Inosine Substitutions in RNA Activate Latent G-Quadruplexes.
Journal of the American Chemical Society, 2021 It is well-accepted that gene expression is heavily influenced by RNA structure. For instance, stem-loops and G-quadruplexes (rG4s) are dynamic motifs in mRNAs that influence gene expression.
T. Hagen +9 more
semanticscholar +1 more source
Foods, 2020 Currently, soybean meal constitutes the main protein source for poultry production. However, the environmental and social issues related to soybean production are calling for more sustainable protein sources that can offset soybean requirements in animal
Vasiliki Gkarane +3 more
doaj +1 more source