Results 41 to 50 of about 7,394 (114)
Elucidation of the Epitranscriptomic RNA Modification Landscape of Chikungunya Virus
VirusesThe genomes of positive-sense (+) single-stranded RNA (ssRNA) viruses are believed to be subjected to a wide range of RNA modifications. In this study, we focused on the chikungunya virus (CHIKV) as a model (+) ssRNA virus to study the landscape of viral
Belinda Baquero-Pérez +7 more
doaj +1 more source
Life, 2019 A mixture of sugar diphosphates is produced in reactions between small aldehyde phosphates catalysed by layered double hydroxide (LDH) clays under plausibly prebiotic conditions.
Harold S. Bernhardt
doaj +1 more source
The degradation of inosine and guanosine by DM9218.
, 2014 (a) Control: inosine and guanosine solution without inoculation of bacteria (270 µL of the inosine and guanosine solution was incubated at 37°C for 60 min, after that 30 µL HClO4 was added, 20 µL of the mixture was analyzed by HPLC).
Dianbin Yang (625123) +5 more
core +1 more source
The Role of Inosine in Adipose Tissue Metabolism [PDF]
, 2022 During the last decades, obesity has become a pandemic disease, associated with severe comorbidities, and a major problem for health care systems. Obesity results from energy imbalance, when energy intake exceeds energy expenditure.
Niemann, Birte
core
Inosine treatment decreases TRPV1 immunoreactivity following spinal cord injury.
, 2015 Representative photomicrographs of staining for the C fiber marker TRPV1 (red) in bladders from SCI rats treated with vehicle or inosine or non-surgical controls are shown.
Debra Franck (284585) +11 more
core +1 more source
, 2000 Gluco- and ribosylation of the bases of sugar protected inosine and uridine were investigated, obtaining only adducts with beta -configuration at thenew glycosidic carbon; stereospecific insertion of a sugar moiety at the 1-N of inosine was achieved ...
DE NAPOLI, LORENZO +5 more
core +2 more sources
Frontiers in NutritionIntroductionMetabolism-associated fatty liver disease (MAFLD) has emerged as a severe worldwide public health burden with insufficient available clinical therapeutic strategies, which underscores the urgent demand for safe, natural dietary interventions.
Yanyan Gao +20 more
doaj +1 more source
Use of inosine for the treatment of t-reg deficiency
, 2023 The present invention provides the use of inosine in the treatment of a disease associated with Treg deficiency or Treg dysfunction, in particular immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX).
Sveriges lantbruksuniversitet. +1 more
core
Renal FailureObjectives It is unknown when inosine was first employed as a renoprotective agent in the context of kidney transplantation procedures. However, there is no clinical evidence to support a protective role of inosine.
You Luo +5 more
doaj +1 more source
Veterinární Medicína, 2015 Inosine is a naturally occurring purine nucleoside, the effect of which was discovered only in recent decades. It has potential to prevent neuronal and glial death and can stimulate axonal outgrowth. This study evaluated the effect of inosine (400 mg per
V. Ledecky +3 more
doaj +1 more source