Results 51 to 60 of about 7,394 (114)

Cloning and expression of recombinant purine nucleoside phosphorylase in the methylotrophic yeast Pichia pastoris

open access: yesJournal of Advanced Biotechnology and Experimental Therapeutics, 2023
Purine Nucleoside Phosphorylase (PNP) is an enzyme involved in biosynthetic pathway of purine nucleosides. Purine nucleoside phosphorylase catalyzes the cleavage of the glycosidic bond of ribo- or deoxyribonucleosides to form the purine base and ...
Jaloliddin Abdurakhmanov   +12 more
doaj   +1 more source

Inosine transiently decreases coronary flow but potentiates vasodilation by adenosine

open access: yes, 1990
To test whether inosine interferes with the action of adenosine, we investigated the effects of intracoronary administration of inosine, adenosine, 8-phenyltheophylline, and adenosine deaminase on isolated rat heart. Inosine did not change heart rate or
J. W. de Jong, P. Van der Meer
core   +1 more source

Inosine-Induced Base Pairing Diversity during Reverse Transcription

open access: yes
A-to-I editing catalyzed by adenosine deaminase acting on RNAs impacts numerous physiological and biochemical processes that are essential for cellular functions and is a big contributor to the infectivity of certain RNA viruses.
Sweta Vangaveti (3932504)   +3 more
core   +1 more source

Multi-Substrate Specificity and the Evolutionary Basis for Interdependence in tRNA Editing and Methylation Enzymes

open access: yesFrontiers in Genetics, 2019
Among tRNA modification enzymes there is a correlation between specificity for multiple tRNA substrates and heteromultimerization. In general, enzymes that modify a conserved residue in different tRNA sequences adopt a heterodimeric structure. Presumably,
Sameer Dixit   +2 more
doaj   +1 more source

Therapeutic value of serum uric acid levels increasing in the treatment of multiple sclerosis [PDF]

open access: yesVojnosanitetski Pregled, 2006
Background/Aim. Uric acid was successfully used in both, prevention and treatment of the animal model of multiple sclerosis (MS). Recently it has been shown that inosine, a ribosylated precursor of uric acid, might be used to elevate serum uric acid ...
Tončev Goran
doaj   +1 more source

Site-specific isotope-labeling of inosine phosphoramidites and NMR analysis of an inosine-containing RNA duplex.

open access: yes, 2016
Structural features and internal dynamics of inosine-containing RNAs are poorly understood. NMR studies of such RNAs require 13C,15N-labeling, which cannot be achieved using in vitro transcription as inosine and guanosine are not distinguished by RNA ...
Michael Sattler   +13 more
core   +1 more source

Identification of Adenosine-to-Inosine RNA Editing with Acrylonitrile Reagents [PDF]

open access: yes, 2019
New chemical probes have been designed to facilitate the identification of adenosine-to-inosine (A-to-I) edited RNAs. These reagents combine a conjugate acceptor for selective inosine covalent modification with functional groups for bioorthogonal ...
Li, Ying   +4 more
core   +2 more sources

Comparison of the effects of copper chlorophyllin, riboxin, indralin and the combined use of glutathione and ascorbic acid on the survival of mice during fractionated X-ray irradiation

open access: yesРазработка и регистрация лекарственных средств
Introduction. The problem of effectiveness and safe pharmacological means of reducing the consequences of exposure to the ionizing effect is becoming increasingly urgent.
L. A. Romodin   +4 more
doaj   +1 more source

Effects of Succinate-Based Antioxidant on in vitro Conversion of Methemoglobin in Oxyhemoglobin

open access: yesОбщая реаниматология, 2018
The purpose of the study — to determine the feasibility of using the succinate-based antioxidant for the in vitro reduction of excessive methemoglobin to oxyhemoglobin in blood.Materials and Methods. Blood sampling was performed in five healthy donors in
A. M. Chernysh   +6 more
doaj   +1 more source

Association of Inosine and Cytidine

open access: yes, 1971
A rigorous theory for the analysis of an associating system involving two different monomer units, which may also undergo self-association, has been developed.
Kolinski, R., Magar, M.E., Steiner, R.F.
core   +1 more source

Home - About - Disclaimer - Privacy