Results 51 to 60 of about 7,394 (114)
Purine Nucleoside Phosphorylase (PNP) is an enzyme involved in biosynthetic pathway of purine nucleosides. Purine nucleoside phosphorylase catalyzes the cleavage of the glycosidic bond of ribo- or deoxyribonucleosides to form the purine base and ...
Jaloliddin Abdurakhmanov +12 more
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Inosine transiently decreases coronary flow but potentiates vasodilation by adenosine
To test whether inosine interferes with the action of adenosine, we investigated the effects of intracoronary administration of inosine, adenosine, 8-phenyltheophylline, and adenosine deaminase on isolated rat heart. Inosine did not change heart rate or
J. W. de Jong, P. Van der Meer
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Inosine-Induced Base Pairing Diversity during Reverse Transcription
A-to-I editing catalyzed by adenosine deaminase acting on RNAs impacts numerous physiological and biochemical processes that are essential for cellular functions and is a big contributor to the infectivity of certain RNA viruses.
Sweta Vangaveti (3932504) +3 more
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Among tRNA modification enzymes there is a correlation between specificity for multiple tRNA substrates and heteromultimerization. In general, enzymes that modify a conserved residue in different tRNA sequences adopt a heterodimeric structure. Presumably,
Sameer Dixit +2 more
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Therapeutic value of serum uric acid levels increasing in the treatment of multiple sclerosis [PDF]
Background/Aim. Uric acid was successfully used in both, prevention and treatment of the animal model of multiple sclerosis (MS). Recently it has been shown that inosine, a ribosylated precursor of uric acid, might be used to elevate serum uric acid ...
Tončev Goran
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Structural features and internal dynamics of inosine-containing RNAs are poorly understood. NMR studies of such RNAs require 13C,15N-labeling, which cannot be achieved using in vitro transcription as inosine and guanosine are not distinguished by RNA ...
Michael Sattler +13 more
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Identification of Adenosine-to-Inosine RNA Editing with Acrylonitrile Reagents [PDF]
New chemical probes have been designed to facilitate the identification of adenosine-to-inosine (A-to-I) edited RNAs. These reagents combine a conjugate acceptor for selective inosine covalent modification with functional groups for bioorthogonal ...
Li, Ying +4 more
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Introduction. The problem of effectiveness and safe pharmacological means of reducing the consequences of exposure to the ionizing effect is becoming increasingly urgent.
L. A. Romodin +4 more
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Effects of Succinate-Based Antioxidant on in vitro Conversion of Methemoglobin in Oxyhemoglobin
The purpose of the study — to determine the feasibility of using the succinate-based antioxidant for the in vitro reduction of excessive methemoglobin to oxyhemoglobin in blood.Materials and Methods. Blood sampling was performed in five healthy donors in
A. M. Chernysh +6 more
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Association of Inosine and Cytidine
A rigorous theory for the analysis of an associating system involving two different monomer units, which may also undergo self-association, has been developed.
Kolinski, R., Magar, M.E., Steiner, R.F.
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