Results 31 to 40 of about 7,394 (114)

Inosine improves neurogenic detrusor overactivity.

open access: yes, 2015
(A) Representative cystometrograms of rats with transection or compression spinal cord injury that received vehicle (upper panels) or inosine (225 mg/kg, lower panels) i.p. daily for 6 wk, either immediately at the time of injury (left and middle panels)
Debra Franck (284585)   +11 more
core   +1 more source

A inosina previne alterações comportamentais e bioquímicas induzidas pelo metilmercúrio em camundongos [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.Introdução: O metilmercúrio (MeHg) tem sido especulado como contaminante ambiental envolvido em
Macedo Júnior, Sérgio José
core  

Influence of nonsteroid anabolic inosine on manifestation of the effects of dexamethasone on skeletal muscle of white rats

open access: yesБіологічні студії, 2012
In experiments on young rat females, it has been established, that the nonsteroid anabolic inosine caused in the case of complex application with dexamethasone the increasing of a specific fraction of slow or intermediate type of fibers in initially ...
V. V. Trush
doaj   +1 more source

Inosine in DNA and RNA

open access: yes, 2014
Deamination of the nucleobases in DNA and RNA is a result of spontaneous hydrolysis, endogenous or environmental factors as well as deaminase enzymes. Adenosine is deaminated to inosine which is miscoding and preferentially base pairs with cytosine.
Alseth, Ingrun   +2 more
core   +1 more source

Xanthine Oxidoreductase: A Double-Edged Sword in Neurological Diseases

open access: yesAntioxidants
Non-communicable neurological disorders are the second leading cause of death, and their burden continues to increase as the world population grows and ages.
Massimo Bortolotti   +3 more
doaj   +1 more source

Germination of Bacillus cereus spores in response to L-alanine and to inosine: the roles of gerL and gerQ operons [PDF]

open access: yes, 2002
Bacillus cereus 569 (ATCC 10876) endospores germinate in response to inosine or L-alanine, the most rapid germination response being elicited by a combination of these germinants.
Clements, M.O.   +3 more
core  

Inhibition of inosine monophosphate dehydrogenase reduces adipogenesis and diet-induced obesity

open access: yes, 2009
We previously described a putative role for inosine monophosphate dehydrogenase (IMPDH), a rate-limiting enzyme in de novo guanine nucleotide biosynthesis, in lipid accumulation.
Hutley, Louise J.   +12 more
core   +1 more source

Metabolic engineering of the purine biosynthetic pathway in Corynebacterium glutamicum results in increased intracellular pool sizes of IMP and hypoxanthine [PDF]

open access: yes, 2012
Background: Purine nucleotides exhibit various functions in cellular metabolism. Besides serving as building blocks for nucleic acid synthesis, they participate in signaling pathways and energy metabolism.
Sarah Zimmet   +11 more
core   +1 more source

The evolution and implications of the inosine tRNA modification [PDF]

open access: yes
Ever since the legendary publication by Francis Crick in JMB introducing the wobble hypothesis in 1966, inosine has been a permanent part of molecular biology.
Gulik, P.T.S. (Peter) van der   +1 more
core   +1 more source

Development of an Inosine Hyperproducer from Bacillus licheniformis by Systems Metabolic Engineering

open access: yes, 2023
Inosine is widely used in food, chemical, and medicine. This study developed Bacillus licheniformis into an inosine hyperproducer through systems metabolic engineering.
Shouwen Chen (3550844)   +9 more
core   +1 more source

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