Results 71 to 80 of about 66,823 (327)

Sensory and ATP derivative-based indicators for assessing the freshness of Atlantic salmon (Salmo salar) and cod (Gadus morhua) [PDF]

open access: yes, 2019
peer-reviewedIrish Journal of Agricultural and Food Research | Volume 58: Issue 1 Sensory and ATP derivative-based indicators for assessing the freshness of Atlantic salmon (Salmo salar) and cod (Gadus morhua)
Bolton, Declan   +4 more
core   +1 more source

Fructose promotes more than glucose the adipocytic differentiation of pig mesenchymal stem cells

open access: yesJournal of Food Biochemistry, Volume 46, Issue 12, December 2022., 2022
This work show the effect of fructose on adipose differentiation. High levels of fructose increase the expansion of genes such as C/EBPβ, PPARγ, and NOX4 as well as the increase in XOR activity and high production of ROS during the differentiation process.
Francisco Campos‐Maldonado   +6 more
wiley   +1 more source

Meta-analytical evaluation of the clinical efficacy of a complex metabolic neuroprotector in patients with chronic cerebral ischemia

open access: yesАнтибиотики и Химиотерапия, 2022
The aim of the study is to evaluate the clinical efficacy, safety, and impact of the complex metabolic neuroprotector on the patients’ quality of life (CMN) Cytoflavin in tablets, as well as in the course of stepwise pharmacotherapy of patients with ...
M. V. Zhuravleva   +5 more
doaj   +1 more source

Arabidopsis thaliana endonuclease V is a ribonuclease specific for inosine-containing single-stranded RNA

open access: yesOpen Biology, 2021
Endonuclease V is highly conserved, both structurally and functionally, from bacteria to humans, and it cleaves the deoxyinosine-containing double-stranded DNA in Escherichia coli, whereas in Homo sapiens it catalyses the inosine-containing single ...
Megumi Endo   +4 more
doaj   +1 more source

Sleep-wake sensitive mechanisms of adenosine release in the basal forebrain of rodents : an in vitro study [PDF]

open access: yes, 2013
Adenosine acting in the basal forebrain is a key mediator of sleep homeostasis. Extracellular adenosine concentrations increase during wakefulness, especially during prolonged wakefulness and lead to increased sleep pressure and subsequent rebound sleep.
A Alonso   +72 more
core   +2 more sources

The inosine conundrum [PDF]

open access: yesScience-Business eXchange, 2009
A new study of inosine in a rat stroke model gives more impetus for studies in humans. But the path forward is uncertain as Alseres Pharmaceuticals needs a partner to develop the compound in the clinic, where key questions about delivery and the treatment window must be worked out.
openaire   +2 more sources

Wakefulness affects synaptic and network activity by increasing extracellular astrocyte-derived adenosine [PDF]

open access: yes, 2012
Loss of sleep causes an increase in sleep drive and deficits in hippocampal-dependent memory. Both of these responses are thought to require activation of adenosine A1 receptors (adorA1Rs) and release of transmitter molecules including ATP, which is ...
Dale, Nicholas   +3 more
core   +2 more sources

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

open access: yesMolecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang   +8 more
wiley   +1 more source

Identification and rescue of a tRNA wobble inosine deficiency causing intellectual disability disorder

open access: yesRNA: A publication of the RNA Society, 2020
The deamination of adenosine to inosine at the wobble position of tRNA is an essential post-transcriptional RNA modification required for wobble decoding in bacteria and eukaryotes.
Jillian Ramos   +10 more
semanticscholar   +1 more source

A Smartphone Application as an Exploratory Endpoint in a Phase 3 Parkinson’s Disease Clinical Trial: A Pilot Study

open access: yesDigital Biomarkers, 2022
Background: Smartphones can generate objective measures of Parkinson’s disease (PD) and supplement traditional in-person rating scales. However, smartphone use in clinical trials has been limited.
Alex Page   +8 more
doaj   +1 more source

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