Results 11 to 20 of about 331,728 (400)

Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate [PDF]

open access: yesInternational Journal of Endocrinology, 2016
Inositols (myo-inositol and inositol hexakisphosphate) exert a wide range of critical activities in both physiological and pathological settings. Deregulated inositol metabolism has been recorded in a number of diseases, including cancer, where inositol modulates different critical pathways.
BIZZARRI, Mariano   +3 more
openaire   +5 more sources

Inositols in PCOS [PDF]

open access: yesMolecules, 2020
(1) Background: Myoinositol (MI) and D-chiro-inositol (DCI) are involved in a number of biochemical pathways within oocytes having a role in oocyte maturation, fertilization, implantation, and post-implantation development. Both inositols have a role in insulin signaling and hormonal synthesis in the ovaries.
Zdravko Kamenov, Antoaneta Gateva
openaire   +4 more sources

Inositol is an effective and safe treatment in polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials

open access: yesReproductive Biology and Endocrinology, 2023
Background Metformin is the gold standard insulin sensitizer, which is widely used to treat insulin resistance in polycystic ovary syndrome (PCOS). However, metformin may induce gastrointestinal side effects. Objective Inositols have long been debated as
Dorina Greff   +11 more
semanticscholar   +1 more source

Conversion of dietary inositol into propionate and acetate by commensal Anaerostipes associates with host health

open access: yesNature Communications, 2021
We describe the anaerobic conversion of inositol stereoisomers to propionate and acetate by the abundant intestinal genus Anaerostipes. A inositol pathway was elucidated by nuclear magnetic resonance using [13C]-inositols, mass spectrometry and ...
T. Bui   +9 more
semanticscholar   +1 more source

Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women with PCOS: a network meta-analysis

open access: yesReproductive Health, 2021
Background Multiple oral insulin-sensitizing agents, such as metformin, thiazolidinediones, inositols, and berberine, have been proven safe and efficacious in improving the endocrine, metabolic, and reproductive abnormalities seen in polycystic ovary ...
Han Zhao, C. Xing, Jiaqi Zhang, B. He
semanticscholar   +1 more source

Scientific Opinion on the safety and efficacy of inositol as a feed additive for fish, dogs and cats [PDF]

open access: yesEFSA Journal, 2014
Inositol is an essential micronutrient for salmon, carp, tilapia and shrimps, particularly juveniles. This conclusion is extended to all fish and crustaceans.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

How do new therapeutic strategies for PCOS management influence the health of the affected individuals? The narrative review

open access: yesJournal of Education, Health and Sport, 2022
Introduction and purpose: Management of polycystic ovary syndrome (PCOS) is difficult since the exact pathogenic mechanism has not been established yet.
Aleksandra Wójcik   +4 more
doaj   +1 more source

General amyloid inhibitors? A critical examination of the inhibition of IAPP amyloid formation by inositol stereoisomers. [PDF]

open access: yes, 2014
Islet amyloid polypeptide (IAPP or amylin) forms amyloid deposits in the islets of Langerhans; a process that is believed to contribute to the progression of type 2 diabetes and to the failure of islet transplants.
Raleigh, David, Wang, Hui
core   +5 more sources

Phosphatidylinositol (4,5)-bisphosphate turnover by INP51 regulates the cell wall integrity pathway in "Saccharomyces cerevisiae" [PDF]

open access: yes, 2004
Signal transduction pathways are important for the cell to transduce external or internal stimuli where second messengers play an important role as mediators of the stimuli. One important group of second messengers are the phosphoinositide family present
Morales-Johansson, Helena
core   +2 more sources

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