Results 11 to 20 of about 270,142 (371)

Systematic analysis of the biological roles and pharmacological properties of D-chiro-inositol [PDF]

open access: yesГинекология, 2020
D-chiroinositol (DCI) is one of the 9 inositol isomers that forms inositol phosphoglycans, which are mediators of the action of insulin. The metabolism of DCI and myo-inositol (MI) is impaired against the background of insulin resistance, including the ...
Olga A. Gromova   +4 more
doaj   +1 more source

Scientific Opinion on the safety and efficacy of inositol as a feed additive for fish, dogs and cats [PDF]

open access: yesEFSA Journal, 2014
Inositol is an essential micronutrient for salmon, carp, tilapia and shrimps, particularly juveniles. This conclusion is extended to all fish and crustaceans.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)
doaj   +1 more source

Myo-Inositol as a Key Supporter of Fertility and Physiological Gestation

open access: yesPharmaceuticals, 2021
Pregnancy is a complex process, featuring several necessary changes in women’s physiology. Most women undergo healthy pregnancies; even so, several women experience reduced fertility or pathologies related to the pregnancy. In the last years, researchers
Riccardo Gambioli   +4 more
doaj   +1 more source

Metabolism and Functions of Inositol Pyrophosphates: Insights Gained from the Application of Synthetic Analogues

open access: yesMolecules, 2020
Inositol pyrophosphates (PP-InsPs) comprise an important group of intracellular, diffusible cellular signals that a wide range of biological processes throughout the yeast, plant, and animal kingdoms.
Stephen B. Shears, Huanchen Wang
doaj   +1 more source

Down-Regulation of Inpp5e Associated With Abnormal Ciliogenesis During Embryonic Neurodevelopment Under Inositol Deficiency

open access: yesFrontiers in Neurology, 2021
The inositol polyphosphate-5-phosphatase E (Inpp5e) gene is located on chromosome 9q34.3. The enzyme it encodes mainly hydrolyzes the 5-phosphate groups of phosphatidylinositol (3,4,5)-trisphosphate (PtdIns (3,4,5) P3) and phosphatidylinositol (4,5 ...
Huixuan Yue   +15 more
doaj   +1 more source

Inositol supplementation - known and possible applications

open access: yesJournal of Education, Health and Sport, 2022
Introduction: Myo-inositol (MYO) and D-chiro-inositol are chemical compounds known to exert an impact on multiple signaling pathways of a human body. Due to its effects on insulin metabolism and ovaries’ hormone activity their use in polycystic ovary ...
Aleksandra Swora   +9 more
doaj   +1 more source

Transition behavior of the seizure dynamics modulated by the astrocyte inositol triphosphate noise [PDF]

open access: yes, 2021
Epilepsy is a neurological disorder with recurrent seizures of complexity and randomness. Until now, the mechanism of epileptic randomness has not been fully elucidated. Inspired by the recent finding that astrocyte GTPase-activating protein (G-protein)-coupled receptors could be involved in stochastic epileptic seizures, we proposed a neuron-astrocyte
arxiv   +1 more source

Inositols in Insulin Signaling and Glucose Metabolism [PDF]

open access: yes, 2018
In the past decades, both the importance of inositol for human health and the complex interaction between glucose and inositol have been the subject of increasing consideration. Glucose has been shown to interfere with cellular transmembrane transport of
Bevilacqua, Arturo, Bizzarri, Mariano
core   +1 more source

A genome-wide dsRNA library screen for Drosophila genes that regulate the GBP/phospholipase C signaling axis that links inflammation to aging

open access: yesBMC Research Notes, 2018
Objective Invertebrates are productive models for understanding how inflammation, metabolism and aging are intertwined. We have deployed a dsRNA library screen to search for genes in Drosophila melanogaster—and hence identify human orthologs—that encode ...
Eui Jae Sung, Stephen B. Shears
doaj   +1 more source

Correction: D-pinitol, a highly valuable product from carob pods: Health-promoting effects and metabolic pathways of this natural super-food ingredient and its derivatives

open access: yesAIMS Agriculture and Food, 2021
The purpose of this note is to give some corrections for our published article in [1].
José Ignacio López-Sánchez   +2 more
doaj   +1 more source

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