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The analysis of myo-inositol phosphates (InsPs) and myo-inositol pyrophosphates (PP-InsPs) is a daunting challenge due to the large number of possible isomers, the absence of a chromophore, the high charge density, the low abundance, and the instability ...
Danye Qiu +2 more
exaly +2 more sources
Jasmonate perception by inositol-phosphate-potentiated COI1–JAZ co-receptor
Jasmonates are a family of plant hormones that regulate plant growth, development and responses to stress. The F-box protein CORONATINE INSENSITIVE 1 (COI1) mediates jasmonate signalling by promoting hormone-dependent ubiquitylation and degradation of ...
Xu Tan, Haibin Mao, Fong-Fu Hsu
exaly +2 more sources
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Inositol treatment raises CSF inositol levels
Brain Research, 1993Inositol is a key precursor for synthesis of phosphatidylinositol in a major second messenger signalling system. It is biologically active in syndromes such as respiratory distress syndrome but has been thought to be excluded from CNS by the blood-brain barrier.
J, Levine +7 more
openaire +2 more sources
Inositol polyphosphate multikinase regulates inositol 1,4,5,6-tetrakisphosphate
Biochemical and Biophysical Research Communications, 2006The human inositol phosphate multikinase (IPMK, 5-kinase) has a preferred 5-kinase activity over 3-kinase and 6-kinase activities and a substrate preference for inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4) over inositol 1,4,5-trisphosphate (Ins(1,4,5)P3) and inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4).
Shao-Chun, Chang, Philip W, Majerus
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Journal of Maternal-Fetal & Neonatal Medicine, 2020
Objective: To identify the effects of different dietary inositol stereoisomers on insulin resistance and the development of gestational diabetes mellitus (GDM) in women at high risk for this disorder.
C. Celentano +6 more
semanticscholar +1 more source
Objective: To identify the effects of different dietary inositol stereoisomers on insulin resistance and the development of gestational diabetes mellitus (GDM) in women at high risk for this disorder.
C. Celentano +6 more
semanticscholar +1 more source
Inositol, lithium, and the brain.
Psychopharmacology bulletinThis review of the background and present state of knowledge of the interactions of inositol metabolism and lithium commemorates the 150th anniversaries of the discovery of inositol and, independently, of first attempts to use lithium as a therapeutic ...
Agranoff Bw, Fisher Sk
semanticscholar +1 more source
Cerebral Lithium, Inositol and Inositol Monophosphates
Pharmacology & Toxicology, 1991Abstract:Cerebral regional inositol, inositol‐1‐phosphate (InslP), and inositol‐4‐phosphate (Ins4P), intermediates in phosphoinositide (PI) cycle, and brain lithium levels were studied in male HamWistar rats 24 hr after an intraperitoneal injection of a single dose (2, 5–1. mEq./kg) of LiCl.
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INOSITOL PHOSPHATE BIOCHEMISTRY
Annual Review of Biochemistry, 1992PERSPECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 C ONVENTIONAL PHOSPHA TIDYLIN OSITOLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226 PHOSPHOLIPASE C . . . . . . . . . .
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Insights into the activation mechanism of class I HDAC complexes by inositol phosphates
Histone deacetylases (HDACs) 1, 2 and 3 form the catalytic subunit of several large transcriptional repression complexes. Unexpectedly, the enzymatic activity of HDACs in these complexes has been shown to be regulated by inositol phosphates, which bind ...
Christopher J Millard +2 more
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Alpha-lactalbumin Effect on Myo-inositol Intestinal Absorption: In vivo and In vitro.
Current Drug Delivery, 2018BACKGROUND Myo-inositol is a natural molecule with important therapeutic applications and an impaired oral absorption may result in a reduced clinical effect. Aim of this study was to determine if the combined oral administration of α-lactalbumin and myo-
G. Monastra +4 more
semanticscholar +1 more source

