Results 121 to 130 of about 2,887 (163)

Inositol Hexakisphosphate Kinase-2 in Cerebellar Granule Cells Regulates Purkinje Cells and Motor Coordination via Protein 4.1N. [PDF]

J Neurosci, 2018
Nagpal L, Fu C, Snyder SH.
europepmc   +1 more source

Multiple aspects of male germ cell development and interactions with Sertoli cells require inositol hexakisphosphate kinase-1. [PDF]

Sci Rep, 2018
Fu C, Rojas T, Chin AC, Cheng W, Bernstein IA, Albacarys LK, Wright WW, Snyder SH.   +7 more
europepmc   +1 more source

Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells.

Cell Signal, 2018
Rajasekaran SS, Kim J, Gaboardi GC, Gromada J, Shears SB, Dos Santos KT, Nolasco EL, Ferreira SS, Ferreira SS, Illies C, Köhler M, Gu C, Ryu SH, Martins JO, Darè E, Barker CJ, Berggren PO.   +16 more
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Corrigendum to 'Inositol hexakisphosphate kinase 1 is a metabolic sensor in pancreatic β-cells' [Cellular Signalling 46 (2018) 120-128].

Cell Signal, 2019
Rajasekaran SS, Kim J, Gaboardi GC, Gromada J, Shears SB, Dos Santos KT, Nolasco EL, de Souza Ferreira S, Illies C, Köhler M, Gu C, Ryu SH, Martins JO, Darè E, Barker CJ, Berggren PO.   +15 more
europepmc   +1 more source

Assessing the omnipotence of inositol hexakisphosphate [PDF]

Cellular Signalling, 2001
This review assesses the authenticity of inositol hexakisphosphate (InsP(6)) being a wide-ranging regulator of many important cellular functions. Against a background in which the possible importance of localized InsP(6) metabolism is discussed, there is the facile explanation that InsP(6) is merely an "inactive" precursor for the diphosphorylated ...
Stephen B Shears
exaly   +3 more sources

Absence of detectable inositol hexakisphosphate (phytate) in plasma

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2014
A critical evaluation of a recent attempt to measure inositol hexakisphosphate (IP6) in mammalian plasma by mass spectroscopy leads to the conclusion that as yet there is no unambiguous evidence that plasma contains any IP6.
Robin F Irvine
exaly   +3 more sources

PiUS (Pi uptake stimulator) is an inositol hexakisphosphate kinase [PDF]

FEBS Letters, 1999
A cDNA cloned from its ability to stimulate inorganic phosphate uptake in Xenopus oocytes (phosphate uptake stimulator (PiUS)) shows significant similarity with inositol 1,4,5‐trisphosphate 3‐kinase. However, the expressed PiUS protein showed no detectable activity against inositol 1,4,5‐trisphosphate, nor the 1,3,4,5‐ or 3,4,5,6‐isomers of inositol ...
Andrew J Letcher, Charles A Brearley, Jürg Biber   +2 more
exaly   +5 more sources

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Inositol hexakisphosphate kinases promote autophagy

The International Journal of Biochemistry & Cell Biology, 2010
We and other authors have previously reported that increasing cellular diphosphoinositol pentakisphosphate (InsP(7)) levels increases cell sensitivity to cell death. In the present study, we elucidated the relationship between inositol hexakisphosphate kinases (InsP(6)Ks), which form InsP(7), and autophagy using InsP(6)Ks overexpression and disruption ...
Eiichiro, Nagata, Adolfo, Saiardi, Hideo, Tsukamoto, Tadayuki, Satoh, Yoshiko, Itoh, Johbu, Itoh, Mamoru, Shibata, Shunya, Takizawa, Shigeharu, Takagi   +8 more
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The signaling role of inositol hexakisphosphate kinases (IP6Ks)

Advances in Enzyme Regulation, 2011
The past ten years have seen a contained explosion of interest in inositol pyrophosphates. The early cloning of the IP6Ks and the more recent identification of the PP-IP5Ks have allowed the development of essential experimental tools to investigate the physiological role of inositol pyrophosphates.
Cristina, Azevedo, Zsolt, Szijgyarto, Adolfo, Saiardi   +2 more
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myo-Inositol-1,2,3,4,5,6-hexakisphosphate

Phytochemistry, 2003
myo-Inositol-1,2,3,4,5,6-hexakisphosphate (Ins P(6)) was first described as an abundant form of phosphorus in plant seeds and other plant tissues and dubbed "phytic acid". Subsequently it was found to be a common constituent in eukaryotic cells, its metabolism a basic component of cellular housekeeping.
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