Results 111 to 120 of about 6,478 (207)
Inositol hexakisphosphate excites rat medullary sympathoexcitatory neurons in vivo
European Journal of Pharmacology, 1992 Inositol hexakisphosphate (IP6) was microinjected into the rostral ventrolateral reticular nucleus or iontophoresed onto reticulospinal sympathoexcitatory neurons of the nucleus in anesthetized rats. IP6 (5-500 pmol) induced a dose-dependent potent and prolonged elevation of arterial pressure which was mimicked by microinjection of ethyleneglycol-bis ...
M K, Sun, C, Wahlestedt, D J, Reis
openaire +2 more sources
Histone Potentiates Inositol Hexakisphosphate in Inducing Apoptosis of HONE-1 Nasopharyngeal Cancer Cells [PDF]
Brazilian Archives of Biology and TechnologyInositol hexakisphosphate (InsP6) requires relatively high concentrations to induce apoptosis of cancer cells, which can possibly cause apoptosis of normal cells.
Ferry Sandra +7 more
doaj +1 more source
International Islamic University Malaysia Engineering Journal, 2011 Phytate or myo-inositol hexakisphosphates (IP6) is widely distributed in plants like rice brans. The production of myo-inositol phosphate intermediates has received much attention due to the remarkable potential health benefits offered by the compounds ...
N. Mohd. Yusoff +7 more
doaj +1 more source
Phytase: application in food industry [PDF]
, 2010 Phytates have been considered as a threat in human diet due to its antinutrients behaviour which known as strong chelators of divalent minerals such as Ca²+, Mg²+, Zn²+ and Fe²+.
Abd. Manap, Mohd. Yazid +3 more
core
Identification of mitogen-activated protein kinase docking sites in enzymes that metabolize phosphatidylinositols and inositol phosphates [PDF]
, 2006 Background Reversible interactions between the components of cellular signaling pathways allow for the formation and dissociation of multimolecular complexes with spatial and temporal resolution and, thus, are an important means of integrating multiple ...
Buckley Colin T +2 more
core +1 more source
Deleting IP6K1 stabilizes neuronal sodium–potassium pumps and suppresses excitability
Molecular BrainInositol pyrophosphates are key signaling molecules that regulate diverse neurobiological processes. We previously reported that the inositol pyrophosphate 5-InsP7, generated by inositol hexakisphosphate kinase 1 (IP6K1), governs the degradation of Na+/K+
Hongfu Jin +5 more
doaj +1 more source
FEBS Open Bio, 2014 Alzheimer’s disease (AD) is widely considered to be caused by amyloid-β peptide (Aβ) accumulation in the brain. Aβ is excised from amyloid-β precursor protein through sequential cleavage by β-secretase 1 (BACE1) and γ-secretase.
Takako K. Abe, Masayuki Taniguchi
doaj +1 more source
The Synthesis of Inositol Hexakisphosphate [PDF]
Journal of Biological Chemistry, 2002 John W. Verbsky +4 more
openaire +1 more source
Inositol hexakisphosphate (IP6) enhances the electrical excitability of Characean Nitellopsis obtusa
Plant StressDespite the importance of action potentials (APs) in plant stress physiology, the molecular identity of Ca2+ channels that initiate APs by passing Ca2+ into the cytoplasm is still unknown in Characean macroalgae. While the Thiel-Beilby mathematical model
Vilmantas Pupkis +3 more
doaj +1 more source
An unconventional gatekeeper mutation sensitizes inositol hexakisphosphate kinases to an allosteric inhibitor. [PDF]
Elife, 2023 Aguirre T +8 more
europepmc +1 more source