Results 21 to 30 of about 2,887 (163)

Phytic Acid against Clostridium perfringens Type A: A Food Matrix Study

Foods, 2022
This study evaluated the inhibitory effect of phytic acid (PA) on the spore germination and vegetative cells growth of Clostridium perfringens type A, as well as its effect in combination with maltodextrin (MD) in cooked sausages.
Ana Paula Marinho Bloot, Daneysa Lahis Kalschne, Diego Ricardo Nunes Nogues, Joana S. Amaral, Eder Lisandro Moraes Flores, Eliane Colla, Sascha Habu, Ilton José Baraldi, Cristiane Canan   +8 more
doaj   +1 more source

Structure of the mature Rous sarcoma virus lattice reveals a role for IP6 in the formation of the capsid hexamer

Nature Communications, 2021
Inositol hexakisphosphate (IP6) is a known assembly cofactor for HIV-1. Here, the authors show the role of IP6 in the assembly of the Rous sarcoma virus (RSV).
Martin Obr, Clifton L. Ricana, Nadia Nikulin, Jon-Philip R. Feathers, Marco Klanschnig, Andreas Thader, Marc C. Johnson, Volker M. Vogt, Florian K. M. Schur, Robert A. Dick   +9 more
doaj   +1 more source

New Frontiers for the Use of IP6 and Inositol Combination in Treating Diabetes Mellitus: A Review

Molecules, 2020
Inositol, or myo-inositol, and associated analog molecules, including myo-inositol hexakisphosphate, are known to possess beneficial biomedical properties and are now being widely studied.
Felix O. Omoruyi, Dewayne Stennett, Shadae Foster, Lowell Dilworth   +3 more
doaj   +1 more source

Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes

STAR Protocols, 2021
Summary: This protocol describes an affinity enrichment approach from mammalian cell extracts to identify protein binding partners of inositol hexakisphosphate (InsP6) and 5-diphosphoinositol pentakisphosphate (5PP-InsP5), two important eukaryotic ...
David Furkert, Michal Nadler-Holly, Dorothea Fiedler   +2 more
doaj   +1 more source

Role of Inositols and Inositol Phosphates in Energy Metabolism

Molecules, 2020
Recently, inositols, especially myo-inositol and inositol hexakisphosphate, also known as phytic acid or IP6, with their biological activities received much attention for their role in multiple health beneficial effects.
Saimai Chatree, Nanthaphop Thongmaen, Kwanchanit Tantivejkul, Chantacha Sitticharoon, Ivana Vucenik   +4 more
doaj   +1 more source

The Pathway for the Production of Inositol Hexakisphosphate in Human Cells [PDF]

Journal of Biological Chemistry, 2005
The yeast and Drosophila pathways leading to the production of inositol hexakisphosphate (InsP(6)) have been elucidated recently. The in vivo pathway in humans has been assumed to be similar. Here we show that overexpression of Ins(1,3,4)P(3) 5/6-kinase in human cell lines results in an increase of inositol tetrakisphosphate (InsP(4)) isomers, inositol
John W, Verbsky, Shao-Chun, Chang, Monita P, Wilson, Yasuhiro, Mochizuki, Philip W, Majerus   +4 more
openaire   +2 more sources

Inositol hexakisphosphate-induced autoprocessing of large bacterial protein toxins. [PDF]

PLoS Pathogens, 2010
Large bacterial protein toxins autotranslocate functional effector domains to the eukaryotic cell cytosol, resulting in alterations to cellular functions that ultimately benefit the infecting pathogen.
Martina Egerer, Karla J F Satchell
doaj   +1 more source

Synthesis and biological evaluation of flavonoid-based IP6K2 inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Inositol polyphosphates (IPs) are a group of inositol metabolites that act as secondary messengers for external signalling cues. They play various physiological roles such as insulin release, telomere length maintenance, cell metabolism, and aging ...
Myunghwan Ahn, Seung Eun Park, Jiyeon Choi, Jiahn Choi, Doyoung Choi, Dongju An, Hayoung Jeon, Soowhan Oh, Kiho Lee, Jaehoon Kim, Jaebong Jang, Seyun Kim, Youngjoo Byun   +12 more
doaj   +1 more source

Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants [PDF]

The Plant Journal, 2014
SummaryInositol pyrophosphates are unique cellular signaling molecules with recently discovered roles in energy sensing and metabolism. Studies in eukaryotes have revealed that these compounds have a rapid turnover, and thus only small amounts accumulate.
Mintu, Desai, Padma, Rangarajan, Janet L, Donahue, Sarah P, Williams, Eric S, Land, Mihir K, Mandal, Brian Q, Phillippy, Imara Y, Perera, Victor, Raboy, Glenda E, Gillaspy   +9 more
openaire   +2 more sources

Structural basis of arrestin-3 activation and signaling

Nature Communications, 2017
While arrestins are mainly associated with GPCR signaling, arrestin-3 can signal independently of receptor interaction. Here the authors present the structure of arrestin-3 bound to inositol hexakisphosphate (IP6) and propose a model for arrestin-3 ...
Qiuyan Chen, Nicole A. Perry, Sergey A. Vishnivetskiy, Sandra Berndt, Nathaniel C. Gilbert, Ya Zhuo, Prashant K. Singh, Jonas Tholen, Melanie D. Ohi, Eugenia V. Gurevich, Chad A. Brautigam, Candice S. Klug, Vsevolod V. Gurevich, T. M. Iverson   +13 more
doaj   +1 more source