Results 21 to 30 of about 6,478 (207)
Inositol Pyrophosphates: Signaling Molecules with Pleiotropic Actions in Mammals
Molecules, 2020 Inositol pyrophosphates (PP-IPs) such as 5-diphosphoinositol pentakisphosphate (5-IP7) are inositol metabolites containing high-energy phosphoanhydride bonds.
Seulgi Lee +3 more
doaj +1 more source
Inositol Phosphates and Retroviral Assembly: A Cellular Perspective
Viruses, 2021 Understanding the molecular mechanisms of retroviral assembly has been a decades-long endeavor. With the recent discovery of inositol hexakisphosphate (IP6) acting as an assembly co-factor for human immunodeficiency virus (HIV), great strides have been ...
Clifton L. Ricaña, Robert A. Dick
doaj +1 more source
A Structural Perspective of the Role of IP6 in Immature and Mature Retroviral Assembly
Viruses, 2021 The small cellular molecule inositol hexakisphosphate (IP6) has been known for ~20 years to promote the in vitro assembly of HIV-1 into immature virus-like particles.
Martin Obr +2 more
doaj +1 more source
Phytic Acid against Clostridium perfringens Type A: A Food Matrix Study
Foods, 2022 This study evaluated the inhibitory effect of phytic acid (PA) on the spore germination and vegetative cells growth of Clostridium perfringens type A, as well as its effect in combination with maltodextrin (MD) in cooked sausages.
Ana Paula Marinho Bloot +8 more
doaj +1 more source
Nature Communications, 2021 Inositol hexakisphosphate (IP6) is a known assembly cofactor for HIV-1. Here, the authors show the role of IP6 in the assembly of the Rous sarcoma virus (RSV).
Martin Obr +9 more
doaj +1 more source
Inositol hexakisphosphate increases the size of platelet aggregates. [PDF]
Biochem Pharmacol, 2019 The inositol phosphates, InsP5 and InsP6, have recently been identified as binding partners of fibrinogen, which is critically involved in hemostasis by crosslinking activated platelets at sites of vascular injury. Here, we investigated the putative physiological role of this interaction and found that platelets increase their InsP6 concentration upon ...
Brehm MA +12 more
europepmc +5 more sources
New Frontiers for the Use of IP6 and Inositol Combination in Treating Diabetes Mellitus: A Review
Molecules, 2020 Inositol, or myo-inositol, and associated analog molecules, including myo-inositol hexakisphosphate, are known to possess beneficial biomedical properties and are now being widely studied.
Felix O. Omoruyi +3 more
doaj +1 more source
Affinity enrichment and identification of inositol poly- and pyrophosphate interactomes
STAR Protocols, 2021 Summary: This protocol describes an affinity enrichment approach from mammalian cell extracts to identify protein binding partners of inositol hexakisphosphate (InsP6) and 5-diphosphoinositol pentakisphosphate (5PP-InsP5), two important eukaryotic ...
David Furkert +2 more
doaj +1 more source
Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants [PDF]
The Plant Journal, 2014 SummaryInositol pyrophosphates are unique cellular signaling molecules with recently discovered roles in energy sensing and metabolism. Studies in eukaryotes have revealed that these compounds have a rapid turnover, and thus only small amounts accumulate.
Mintu, Desai +9 more
openaire +2 more sources
Inositol hexakisphosphate promotes dynamin I- mediated endocytosis [PDF]
Proceedings of the National Academy of Sciences, 2002 Membrane homeostasis is maintained by exocytosis and endocytosis. The molecular mechanisms regulating the interplay between these two processes are not clear. Inositol hexakisphosphate (InsP 6 ) is under metabolic control and serves as a signal in the pancreatic β cell stimulus-secretion coupling by increasing Ca
Marianne, Høy +10 more
openaire +2 more sources