Structural basis of arrestin-3 activation and signaling
Nature Communications, 2017 While arrestins are mainly associated with GPCR signaling, arrestin-3 can signal independently of receptor interaction. Here the authors present the structure of arrestin-3 bound to inositol hexakisphosphate (IP6) and propose a model for arrestin-3 ...
Qiuyan Chen +13 more
doaj +1 more source
Mikrobiyal Fitazlar, Uygulama Alanları ve Biyoteknoloji
Journal of Agricultural Sciences, 2007 Fitazlar, myo-inositol hexakisphosphate phosphohydrolase, EC 3.1.3.8 fitatdan fosfatların serbest kalmasını katalizlerler. Birçok tahıl tanesi, baklagiller ve yağlı tohumlar fosforu fitat olarak depolarlar.
Meltem Aşan
doaj +1 more source
A role for Gle1, a regulator of DEAD-box RNA helicases, at centrosomes and basal bodies. [PDF]
, 2017 Control of organellar assembly and function is critical to eukaryotic homeostasis and survival. Gle1 is a highly conserved regulator of RNA-dependent DEAD-box ATPase proteins, with critical roles in both mRNA export and translation.
Akef, Abdalla +2 more
core +1 more source
Structure-based selection of human metabolite binding P4 pocket of DRB1*15:01 and DRB1*15:03, with implications for multiple sclerosis. [PDF]
, 2018 Binding of small molecules in the human leukocyte antigen (HLA) peptide-binding groove may result in conformational changes of bound peptide and an altered immune response, but previous studies have not considered a potential role for endogenous ...
Damotte, Vincent +2 more
core +1 more source
Pathway of phytate dephosphorylation by β-propeller phytases of different origins [PDF]
, 2007 Using a combination of high-performance ion chromatography analysis and kinetic studies, the pathway of myo-inositol hexakisphosphate dephosphorylation by the P-propeller phytase of Shewanella oneidensis was established, which was then compared with that
Carlsson, NG +3 more
core +1 more source
New insights into the biological role of mammalian ADARs; the RNA editing proteins [PDF]
, 2015 The ADAR proteins deaminate adenosine to inosine in double-stranded RNA which is one of the most abundant modifications present in mammalian RNA.
Arieti, Fabiana +4 more
core +2 more sources
Lactic fermentation as a strategy to improve the nutritional and functional values of pseudocereals [PDF]
, 2019 One of the greatest challenges is to reduce malnutrition worldwide while promoting sustainable agricultural and food systems. This is a daunting task due to the constant growth of the population and the increasing demands by consumers for functional ...
Gerez, Carla Luciana +2 more
core +1 more source
PLoS ONE, 2014 Bdellovibrio bacteriovorus is an unusual δ-proteobacterium that invades and preys on other Gram-negative bacteria and is of potential interest as a whole cell therapeutic against pathogens of man, animals and crops.
Robert J Gruninger +7 more
doaj +1 more source
Inositol hexakisphosphate binding sites in rat heart and brain [PDF]
British Journal of Pharmacology, 1996 . Inositol 1,4,5‐trisphosphate (Ins(1,4,5)P3) and inositol hexakisphosphate (InsP6) are produced in response to stimulation of cardiac α1‐adrenoceptors. While the role of Ins(1,4,5)P3 and Ins(1,4,5)P3 receptors is well‐defined in many tissues including brain, the functional role of the putative InsP6‐InsP6 receptor system in cardiac function is less ...
K G, Rowley +3 more
openaire +2 more sources
Biosynthesis and possible functions of inositol pyrophosphates in plants
Frontiers in Plant Science, 2015 Inositol phosphates (InsPs) are intricately tied to lipid signaling, as at least one portion of the inositol phosphate signaling pool is derived from hydrolysis of the lipid precursor, phosphatidyl inositol (4,5) bisphosphate. The focus of this review is
Sarah Phoebe Williams +2 more
doaj +1 more source