Results 71 to 80 of about 70,433 (242)

Allelic Variants of CRISPR/Cas9 Induced Mutation in an Inositol Trisphosphate 5/6 Kinase Gene Manifest Different Phenotypes in Barley

open access: yesPlants, 2020
Inositol trisphosphate 5/6 kinases (ITPK) constitute a small group of enzymes participating in the sequential phosphorylation of inositol phosphate to inositol hexakisphosphate (IP6), which is a major storage form of phosphate in cereal grains.
Tomáš Vlčko, Ludmila Ohnoutková
doaj   +1 more source

Talented family: Inositol phosphates [PDF]

open access: yesThe Biochemist, 2009
So, what's a review on inositol phosphates doing in a nice lipid-themed place like this? (given how watersoluble and un-lipiddy they are). But they are, at least in animal cells, inextricably linked with inositol lipids. The link is the phospholipase C (PI-PLC) reaction, which splits phosphatidylinositol 4,5-bisphosphate [PtdIns(4,5)P2] into ...
openaire   +1 more source

Inositol phosphate signaling and gibberellic acid [PDF]

open access: yesPlant Signaling & Behavior, 2009
To respond to physical signals and endogenous hormones, plants use specific signal transduction pathways. We and others have previously shown that second messenger inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] is used in abscisic acid (ABA) signaling, and that some mutants with altered Ins(1,4,5)P(3) have altered responses to ABA. Specifically, mutants
Christine M, Fleet   +2 more
openaire   +2 more sources

Functionally complementary bacterial inoculant coordinates arbuscular mycorrhizal fungi to improve Angelica sinensis root yield and quality

open access: yesiMetaOmics, EarlyView.
Comprehensive understanding of how diverse PGPR strains enhance the rhizosphere microenvironment remains a considerable challenge. Here, we provide experimental evidence that a functionally synergistic composite microbial formulation can markedly enhance growth performance and improve the quality attributes in Angelica sinensis.
Zongyu Zhang   +13 more
wiley   +1 more source

Microbial metabolites in tumor epigenetic regulation

open access: yesiMeta, EarlyView.
The gut microbiome modulates tumor epigenetic regulation through bioactive metabolites derived from dietary substrates. Microbiota‐produced SCFAs, secondary BAs, one‐carbon metabolites, and tryptophan‐derived ligands regulate histone acetylation, DNA methylation, and chromatin remodeling via HDAC, DNMT, AhR, and metabolic cofactor‐dependent pathways ...
Wangzheqi Zhang   +31 more
wiley   +1 more source

Inositol pyrophosphates: Why so many phosphates? [PDF]

open access: yesAdvances in Biological Regulation, 2015
The inositol pyrophosphates (PP-InsPs) are a specialized group of "energetic" signaling molecules found in yeasts, plants and animals. PP-InsPs boast the most crowded three dimensional phosphate arrays found in Nature; multiple phosphates and diphosphates are crammed around the six-carbon, inositol ring.
openaire   +2 more sources

Vascular Calcification: Mechanisms, Models, and Therapies

open access: yesiNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu   +5 more
wiley   +1 more source

Inositol Phosphates: A Remarkably Versatile Enzyme [PDF]

open access: yesCurrent Biology, 2002
Ins(3,4,5,6)P(4) is an inhibitor of Ca(2+)-activated Cl(-) channels, but further understanding has been hindered by ignorance of how it is made in cells. It now transpires that one protein with ATP-dependent kinase and phosphatase activities interconverts Ins(3,4,5,6)P(4) and Ins(1,3,4,5,6)P(5), as well as several other inositol polyphosphates.
openaire   +2 more sources

Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira   +9 more
wiley   +1 more source

Do Short‐Term Legume–Maize Sequences Outperform Maize Monoculture Regarding Biomass Production and P Use Efficiency Under P‐Restricted Conditions?

open access: yesJournal of Plant Nutrition and Soil Science, EarlyView.
In a short‐term pot experiment, three legume‐based crop rotations are being tested for their effects on the P cycle and P use efficiency compared to maize monoculture. Legume‐based crop rotations stimulate the P cycle by increasing acid phosphatase activity and carboxylate exudation.
Michelle Natalie Herrmann   +6 more
wiley   +1 more source

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