Results 231 to 240 of about 27,445 (272)
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Phosphatidylinositol and inositol phosphate metabolism
Journal of Cell Science, 2001The six carbons that comprise the inositol ring can be phosphorylated in a combinatorial manner, generating a truly astonishing range of inositol phosphates and inositol lipids. Yet, somehow, the cell can distinguish and utilize several of these metabolites to specifically regulate a variety ...
K, Abel, R A, Anderson, S B, Shears
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Rapid Analysis of Inositol Phosphates
Journal of Agricultural and Food Chemistry, 2001Fast and simple analytical methods for the determination of inositol bis- to hexakisphosphates or only inositol hexakisphosphate in foods and feces are presented. The methods are both faster and simpler with regard to analytical detection and sample pretreatment as compared to previously reported methods. The samples are pretreated using extraction and
N G, Carlsson +4 more
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Mass measurement of inositol phosphates
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1989This review summarises the methods available for the mass measurement of inositol phosphates, i.e., use of radioactive inositol lipid precursors, optical techniques, gas chromatography, mass spectrometry, nuclear magnetic resonance, fast atom bombardment and assays specific for Ins(1,4,5)P3.
Palmer, S, Wakelam, M J
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Paosphorothioate Analogues of Inositol Phosphates
Phosphorus, Sulfur, and Silicon and the Related Elements, 1990Abstract Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.
Allan Cooke +3 more
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Inositol Phosphate Metabolism and Signal Transduction
American Review of Respiratory Disease, 1990Activation of a variety of cell surface receptors results in a biphasic increase in the cytoplasmic Ca2+ concentration, due to the release or mobilization of intracellular Ca2+ stores and to the entry of Ca2+ from the extracellular space. Stimulation of these same receptors also results in the hydrolysis of the minor plasma membrane phospholipid ...
A R, Hughes +3 more
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Gradient ion chromatography of inositol phosphates
Analytical Biochemistry, 1988Inositol phosphates including phytic acid were separated in 30 min by gradient ion chromatography with postcolumn derivatization. All four pentakisphosphates were resolved, while four tetrakisphosphate peaks were detected. The limits of detection for all polyphosphates, including tris- and bisphosphates, were between 1 and 2 nmol.
B Q, Phillippy, J M, Bland
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Inositol Phosphate Metabolism During Myocardial Ischemia
Journal of Molecular and Cellular Cardiology, 1997Inositol phosphate release in intact heart in response to norepinephrine involves primarily release of inositol(1,4)bisphosphate (Ins(1,4)P2) rather than inositol(1,4,5)trisphosphate (Ins(1,4,5)P3) but Ins(1,4,5)P3 release predominates under conditions of post-ischemic reperfusion.
E A, Woodcock +3 more
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Inositol Phosphate Second Messengers
1990Abstract The role of inositol lipid hydrolysis in receptor-mediated cell signalling was first suggested by Michell in the mid-1970s (1). However, the current growth in interest in this subject probably stems from the more recent realization that receptor-mediated hydrolysis of phosphatidylinositol 4,5-bisphosphate [Ptdlns(4,5)P2 ...
C J Kirk, A J Morris,, S B Shears
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Inositol Phosphates: Pinitol 4-Phosphate and (-)-Inositol 3-Phosphate
Journal of the American Chemical Society, 1958Gordon L. Kilgour, Clinton E. Ballou
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