Results 231 to 240 of about 14,137 (280)

INOSITOL PHOSPHATE BIOCHEMISTRY

Annual Review of Biochemistry, 1992
PERSPECTIVES . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 225 C ONVENTIONAL PHOSPHA TIDYLIN OSITOLS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 226 PHOSPHOLIPASE C . . . . . . . . . .
openaire   +2 more sources

Configuration of Inositol Phosphate in Liver Phosphatidyl Inositol

Nature, 1960
THE hydrolysis of synthetic glycerol 1-(inositol 2-phosphate)1,2 has recently been compared with that of the glycerylphosphoryl inositol isolated from hydrolysates of liver phosphatidyl inositol3. The results suggest that the phosphate group in the original lipid is attached to the 1- or 2-hydroxyl of the myoinositol.
J N, HAWTHORNE, P, KEMP, R B, ELLIS
openaire   +2 more sources

Phosphatidylinositol and inositol phosphate metabolism

Journal of Cell Science, 2001
The six carbons that comprise the inositol ring can be phosphorylated in a combinatorial manner, generating a truly astonishing range of inositol phosphates and inositol lipids. Yet, somehow, the cell can distinguish and utilize several of these metabolites to specifically regulate a variety ...
K, Abel, R A, Anderson, S B, Shears
openaire   +2 more sources

Rapid Analysis of Inositol Phosphates

Journal of Agricultural and Food Chemistry, 2001
Fast and simple analytical methods for the determination of inositol bis- to hexakisphosphates or only inositol hexakisphosphate in foods and feces are presented. The methods are both faster and simpler with regard to analytical detection and sample pretreatment as compared to previously reported methods. The samples are pretreated using extraction and
N G, Carlsson, E L, Bergman, E, Skoglund, K, Hasselblad, A S, Sandberg   +4 more
openaire   +2 more sources

Inositol phosphates and cell signalling

Nature, 1989
Inositol 1,4,5-trisphosphate is a second messenger which regulates intracellular calcium both by mobilizing calcium from internal stores and, perhaps indirectly, by stimulating calcium entry. In these actions it may function with its phosphorylated metabolite, inositol 1,3,4,5-tetrakisphosphate. The subtlety of calcium regulation by inositol phosphates
M J, Berridge, R F, Irvine
openaire   +2 more sources

Paosphorothioate Analogues of Inositol Phosphates

Phosphorus, Sulfur, and Silicon and the Related Elements, 1990
Abstract Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.
Allan Cooke, Leroy James, Stefan Nahorski, Barry Potter   +3 more
openaire   +1 more source

Methods for the analysis of inositol phosphates

Analytical Biochemistry, 1989
Interest in the inositol phospholipids was stimulated by the simultaneous discoveries that the products of hydrolysis of these lipids could serve as messengers to activate to synergistic signaling pathways in hormonally responsive cells, namely, inositol 1,4,5-trisphosphate which causes the release of Ca2+ from intracellular stores and diacylglycerol ...
N M, Dean, M A, Beaven
openaire   +2 more sources

A bioautographic method for the identification of inositol and inositol phosphate

Analytical Biochemistry, 1962
Abstract A bioautographic method, utilizing Saccharomyces carlsbergensis strain 4228, was shown to be capable of detecting and distinguishing between myoinositol, myoinositol 2-phosphate, and other derivatives of myoinositol. The method was shown to respond to as little as 1 μg inositol and is effective even in the presence of lipid hydrolyzates.
openaire   +2 more sources

Inositol Phosphates in the Nucleus

Science, 2000
The inositol signaling pathways in the cytoplasm are well characterized. In a Perspective, Chi and Crabtree now explain how similar inositol pathways operate in the nucleus to switch gene expression on and off. One of the key players is the kinase Ipk2p, which might stabilize components of a transcription complex ( Odom et al.).
Tian H. Chi, Gerald R. Crabtree
openaire   +1 more source

Selective recognition of inositol phosphates by subtypes of the inositol trisphosphate receptor

Biochemical Journal, 2001
Synthetic analogues of inositol trisphosphate (IP3), all of which included structures equivalent to the 4,5-bisphosphate of (1,4,5)IP3, were used to probe the recognition properties of rat full-length type 1, 2 and 3 IP3 receptors expressed in insect Spodoptera frugiperda 9 cells.
E P, Nerou, A M, Riley, B V, Potter, C W, Taylor   +3 more
openaire   +2 more sources