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Paosphorothioate Analogues of Inositol Phosphates
Phosphorus, Sulfur, and Silicon and the Related Elements, 1990Abstract Novel analogues of the intracellular second messenger D-myo-inositol 1,4,5-trisphosphate, which possess phosphorothioate groups in place of phosphate groups have been synthesized. They exhibit unusual biological properties which will be of considerable application in understanding the phosphoinositide cycle.
Allan Cooke +3 more
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Methods for the analysis of inositol phosphates
Analytical Biochemistry, 1989Interest in the inositol phospholipids was stimulated by the simultaneous discoveries that the products of hydrolysis of these lipids could serve as messengers to activate to synergistic signaling pathways in hormonally responsive cells, namely, inositol 1,4,5-trisphosphate which causes the release of Ca2+ from intracellular stores and diacylglycerol ...
N M, Dean, M A, Beaven
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A bioautographic method for the identification of inositol and inositol phosphate
Analytical Biochemistry, 1962Abstract A bioautographic method, utilizing Saccharomyces carlsbergensis strain 4228, was shown to be capable of detecting and distinguishing between myoinositol, myoinositol 2-phosphate, and other derivatives of myoinositol. The method was shown to respond to as little as 1 μg inositol and is effective even in the presence of lipid hydrolyzates.
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Inositol Phosphates in the Nucleus
Science, 2000The inositol signaling pathways in the cytoplasm are well characterized. In a Perspective, Chi and Crabtree now explain how similar inositol pathways operate in the nucleus to switch gene expression on and off. One of the key players is the kinase Ipk2p, which might stabilize components of a transcription complex ( Odom et al.).
Tian H. Chi, Gerald R. Crabtree
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The Metabolism of Inositol Phosphates
1988Phosphatidylinositols are phospholipid precursors of a series of inositol phosphates. Several inositol phosphates function as messenger molecules that evoke responses in cells following stimulation by extracellular agonists. While many different compounds are formed, the functions of only a few are understood.
Philip W. Majerus +4 more
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Inositol lipids and phosphates
Current Opinion in Cell Biology, 1990C P, Downes, A N, Carter
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Inositol Phosphates: Pinitol 4-Phosphate and (-)-Inositol 3-Phosphate
Journal of the American Chemical Society, 1958Gordon L. Kilgour, Clinton E. Ballou
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