RNA polymerase interactions and elongation rate [PDF]
We show that non-steric molecular interactions between RNA polymerase (RNAP) motors that move simultaneously on the same DNA track determine strongly the kinetics of transcription elongation. With a focus on the role of collisions and cooperation, we introduce a stochastic model that allows for the exact analytical computation of the stationary ...
arxiv
Plc1p, Arg82p, and Kcs1p, Enzymes Involved in Inositol Pyrophosphate Synthesis, Are Essential for Phosphate Regulation and Polyphosphate Accumulation in Saccharomyces cerevisiae [PDF]
Choowong Auesukaree+4 more
openalex +1 more source
Stable Isotope Phosphate Labelling of Diverse Metabolites is Enabled by a Family of O-18-Phosphoramidites** [PDF]
A family of 18O2-phosphoramidites facilitates synthetic access on gram-scale to various isotopically pure 18O-labelled phosphate products, like nucleotides, inositol phosphates, polyphosphates, and DNA.
Duerr-Mayer, T+9 more
core
IP6K gene identification in plant genomes by tag searching [PDF]
BACKGROUND: Plants have played a special role in inositol polyphosphate (IP) research since in plant seeds was discovered the first IP, the fully phosphorylated inositol ring of phytic acid (IP6).
Fassetti, Fabio+4 more
core +2 more sources
Regulation of a Cyclin-CDK-CDK Inhibitor Complex by Inositol Pyrophosphates [PDF]
Young‐Sam Lee+3 more
openalex +1 more source
Data-driven modelling of the inositol trisphosphate receptor (IPR) and its role in calcium induced calcium release (CICR) [PDF]
We give a review of the current state of the art of data-driven modelling of the inositol trisphosphate receptor (IPR). After explaining that the IPR plays a crucial role as a central regulator in calcium dynamics, several sources of relevant experimental data are introduced.
arxiv
Modeling stochastic Ca$^{2+}$ release from a cluster of IP$_3$-sensitive receptors [PDF]
We focused our attention on Ca$^{2+}$ release from the endoplasmic reticulum through a cluster of inositol 1,4,5-trisphosphate (IP$_3$) receptor channels. The random opening and closing of these receptors introduce stochastic effects that have been observed experimentally.
arxiv
Intercellular synchronization of diffusively coupled astrocytes [PDF]
We examine the synchrony of the dynamics of localized [Ca^{2+}]_i oscillations in internal pool of astrocytes via diffusing coupling of a network of such cells in a certain topology where cytosolic Ca^{2+} and inositol 1,4,5-triphosphate (IP3) are coupling molecules; and possible long range interaction among the cells.
arxiv
Inositol phosphate kinases in the eukaryote landscape [PDF]
Inositol phosphate encompasses a large multifaceted family of signalling molecules that originate from the combinatorial attachment of phosphate groups to the inositol ring. To date, four distinct inositol kinases have been identified, namely, IPK, ITPK,
Desfougères, Y+3 more
core