Intimate connections: Inositol pyrophosphates at the interface of metabolic regulation and cell signaling. [PDF]
Shears SB.
europepmc +1 more source
Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases [PDF]
Sandip Mukherjee +2 more
openalex +1 more source
Biochemical and structural characterization of an inositol pyrophosphate kinase from a giant virus [PDF]
Kinases that synthesize inositol phosphates (IPs) and pyrophosphates (PP-IPs) control numerous biological processes in eukaryotic cells. Herein, we extend this cellular signaling repertoire to viruses. We have biochemically and structurally characterized
Desfougères, Yann +6 more
core
Unconventional signaling properties of inositol pyrophosphates
Inositol pyrophosphates (PP-InsPs) are messenger molecules in eukaryotic cells, that serve as sensors of phosphate and ATP, among other functions, signaling e.g. through allosteric regulation and posttranslational modifications. This work is structured into two parts, focusing on two different unusual features of these molecules.
openaire +1 more source
Affinity-Based Interactome Mapping of Inositol Pyrophosphates Reveals 4/6-PP-InsP 5 –Binding Proteins in Plants [PDF]
Kevin Ritter +9 more
openalex +1 more source
Correction for Lee et al., Inositol pyrophosphates inhibit synaptotagmin-dependent exocytosis. [PDF]
europepmc +1 more source
Inositol pyrophosphates promote tumor growth and metastasis by antagonizing liver kinase B1. [PDF]
Rao F +7 more
europepmc +1 more source
Inositol pyrophosphates regulate RNA polymerase I-mediated rRNA transcription in Saccharomyces cerevisiae. [PDF]
Thota SG +4 more
europepmc +1 more source

