Results 51 to 60 of about 94,332,065 (302)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Antagonistic Magneto-Rheological Actuators with Inherent Output Boundedness: An Ideal Solution for High-Performance and Human-Safe Actuation

open access: yesActuators, 2023
This paper studies the working principles of antagonistic magneto-rheological (MR) actuators, i.e., a combination of an electric motor and a pair of MR clutches in an antagonistic configuration, for compliant actuation in robotics.
Mehrdad R. Kermani   +3 more
doaj   +1 more source

Further input-to-state stability subtleties for discrete-time systems [PDF]

open access: yes, 2013
This technical note considers input-to-state stability analysis of discrete-time systems using continuous Lyapunov functions. The main result reveals a relation between existence of a continuous Lyapunov function and inherent input-to-state stability on ...
Lazar, M Mircea   +5 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A linear dissipativity approach to incremental input-to-state stability for a class of positive Lur’e systems [PDF]

open access: yes
Incremental stability properties are considered for certain systems of forced, nonlinear differential equations with a particular positivity structure. An incremental stability estimate is derived for pairs of input/state/output trajectories of the Lur'e
Piengeon, Violaine; id_orcid   +2 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Input-to-State Stability for Dynamical Neural Networks with Time-Varying Delays

open access: yesAbstract and Applied Analysis, 2012
A class of dynamical neural network models with time-varying delays is considered. By employing the Lyapunov-Krasovskii functional method and linear matrix inequalities (LMIs) technique, some new sufficient conditions ensuring the input-to-state ...
Weisong Zhou, Zhichun Yang
doaj   +1 more source

An Input-to-State Stability Perspective on Robust Locomotion

open access: yesIEEE Control Systems Letters, 2023
6 ...
Maegan Tucker, Aaron D. Ames
openaire   +4 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

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