Results 51 to 60 of about 1,641,408 (306)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Weak input-to-state stability: Characterizations and counterexamples

open access: yes, 2022
S.433-454We establish characterizations of weak input-to-state stability for abstract dynamical systems with inputs, which are similar to characterizations of uniform and of strong input-to-state stability established in a recent paper by A.
Schmid, J.
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Single-Piece State-Space Behavioral Models for IC Output Buffers [PDF]

open access: yes, 2007
In this paper enhancements of parametric behavioral models for the output buffers of digital ICs are explored. A model based on a single-piece structure, which offers improved accuracy in describing state transition events for arbitrary load conditions ...
Savi, Patrizia   +14 more
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Input-to-State Stability for Dynamical Neural Networks with Time-Varying Delays

open access: yesAbstract and Applied Analysis, 2012
A class of dynamical neural network models with time-varying delays is considered. By employing the Lyapunov-Krasovskii functional method and linear matrix inequalities (LMIs) technique, some new sufficient conditions ensuring the input-to-state ...
Weisong Zhou, Zhichun Yang
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Towards ℓ2-stability of discrete-time reset control systems via dissipativity theory [PDF]

open access: yes, 2013
This paper proposes conditions on input-output stability of discrete-time reset systems by using some key dissipativity properties. In the continuous-time setting, dissipativity of the base linear system is preserved under reset actions if the storage ...
Carrasco, Joaquín; id_orcid   +1 more
core   +1 more source

The Stability of the Systems with Command Saturation, Command Delay, and State Delay

open access: yesAutomation, 2022
This article presents the study of the stability of single-input and multiple-input systems with point or distributed state delay and input delay and input saturation.
Marcel Nicola
doaj   +1 more source

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