Results 81 to 90 of about 1,641,408 (306)

Data-driven input-to-state stabilization

CoRR
For the class of nonlinear input-affine systems with polynomial dynamics, we consider the problem of designing an input-to-state stabilizing controller with respect to typical exogenous signals in a feedback control system, such as actuator and process disturbances.
Hailong Chen, Andrea Bisoffi, Claudio De Persis   +2 more
openaire   +2 more sources

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

A linear dissipativity approach to incremental input-to-state stability for a class of positive Lur’e systems

Incremental stability properties are considered for certain systems of forced, nonlinear differential equations with a particular positivity structure. An incremental stability estimate is derived for pairs of input/state/output trajectories of the Lur'e
Piengeon, Violaine; id_orcid, Guiver, Chris, Piengeon, Violaine   +2 more
core   +1 more source

Input-to-State Stability of Nonlinear Switched Systems via Lyapunov Method Involving Indefinite Derivative

Complexity, 2018
This paper studies the input-to-state stability (ISS) of nonlinear switched systems. By using Lyapunov method involving indefinite derivative and average dwell-time (ADT) method, some sufficient conditions for ISS are obtained.
Peng Li, Xiaodi Li, Jinde Cao
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Improved input‐to‐state stability criteria for time‐varying switched singular systems

IET Control Theory & Applications
This paper is dedicated to proposing improved input‐to‐state stability (ISS) criteria for a class of continuous‐time time‐varying switched singular systems (CTSSS) under slow/fast/slow‐fast switching signals.
Junjie Lu, Yongqi Li, Shijie Wang, Zhikun She   +3 more
doaj   +1 more source

Tracking Control of High Order Input Reference Using Integrals State Feedback and Coefficient Diagram Method Tuning

IEEE Access, 2020
The purpose of the research is tracking control to follow the input reference signal such as step, ramp, parabolic, and high order reference stably. The challenge is rising when high order input references, such as parabolic or polynomial, are used in ...
Alfian Ma'Arif, Adha Imam Cahyadi, Samiadji Herdjunanto, Oyas Wahyunggoro   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Stability of Forced Higher-Order Continuous-Time Lur'e Systems: a Behavioural Input-Output Perspective

, 2023
We consider a class of forced continuous-time Lur'e systems obtained by applying nonlinear feedback to a higher-order linear differential equation which defines an input-output system in the sense of behavioural systems theory.
Chris Guiver, Logemann, Hartmut, Guiver, Chris, Hartmut Logemann   +3 more
core   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source