Results 11 to 20 of about 4,048,456 (298)

Palidis: fast discovery of novel insertion sequences [PDF]

Microbial Genomics, 2022
AbstractThe diversity of microbial insertion sequences, crucial mobile genetic elements in generating diversity in microbial genomes, needs to be better represented in current microbial databases. Identification of these sequences in microbiome communities presents some significant problems that have led to their underrepresentation. Here, we present a
Carr, Victoria R., Pissis, Solon P., Mullany, Peter, Shoaie, Saeed, Gomez-Cabrero, David, Moyes, David L.   +5 more
openaire   +7 more sources

The transmembrane serine protease inhibitors are potential antiviral drugs for 2019-nCoV targeting the insertion sequence-induced viral infectivity enhancement

, 2020
In December 2019, 2019 novel coronavirus (2019-nCoV) induced an ongoing outbreak of pneumonia in Wuhan, Hubei, China. It enters into host cell via cellular receptor recognization and membrane fusion.
T. Meng, Hao Cao, Hao Zhang, Zijian Kang, Dan Xu, Haiyi Gong, Jing Wang, Zifu Li, X. Cui, Huji Xu, Haifeng Wei, Xiu-wu Pan, Rongrong Zhu, Jianru Xiao, Wang Zhou, Liming Cheng, Jianmin Liu   +16 more
semanticscholar   +1 more source

Insertion sequence distribution bias in Archaea [PDF]

Mobile Genetic Elements, 2014
Insertion sequences (IS) are common transposable elements in Archaea. Intergenic IS elements are usually less harmful than intragenic ISs, simply because they are less likely to disrupt host gene function. However, because regulatory sequences are intergenic and upstream of genes, we hypothesized that not all intergenic regions are selectively ...
Morgan C, Florek, Daniel P, Gilbert, Gordon R, Plague   +2 more
openaire   +2 more sources

TranspoGene and microTranspoGene: transposed elements influence on the transcriptome of seven vertebrates and invertebrates [PDF]

, 2008
Transposed elements (TEs) are mobile genetic sequences. During the evolution of eukaryotes TEs were inserted into active protein-coding genes, affecting gene structure, expression and splicing patterns, and protein sequences.
Asaf Levy, Biemont, Borchert, Callinan, Clark, Consortium, Dagan, Deininger, Deininger, Gasteiger, Giardine, Gil Ast, Griffiths-Jones, Han, Hedges, Houwing, Johnson, Jordan, Jurka, Karolchik, Kent, Kim, Kim, Kuhn, Lander, Lev-Maor, Lippman, Lorenc, Makalowski, Martignetti, McKusick, Morgan, Noa Sela, Pasyukova, Piriyapongsa, Pruitt, Sayah, Sela, Smalheiser, Smalheiser, Sorek, Sorek, Thornburg, Waterston   +43 more
core   +3 more sources

An age-of-allele test of neutrality for transposable element insertions [PDF]

, 2013
How natural selection acts to limit the proliferation of transposable elements (TEs) in genomes has been of interest to evolutionary biologists for many years.
Bergman, Casey M., Blumenstiel, Justin P., Chen, Xi, He, Miaomiao   +3 more
core   +2 more sources

Palladium‐Catalyzed Carbonylation/Acyl Migratory Insertion Sequence

Angewandte Chemie, 2010
Zhenhua, Zhang, Yiyang, Liu, Mingxing, Gong, Xiaokun, Zhao, Yan, Zhang, Jianbo, Wang   +5 more
openaire   +3 more sources

A Receptor Component of the Chloroplast Protein Translocation Machinery [PDF]

, 1994
The chloroplast outer envelope protein OEP86 functions as a receptor in precursor protein translocation into chloroplasts. Sequence analysis suggests that the precursor of OEP86 is directed to the chloroplast outer envelope by a cleavable, negatively ...
Heemeyer, Frank, Heijne, Gunnar von, Hirsch, Stephan, Muckel, Eva, Soll, Jürgen   +4 more
core   +1 more source

Early steps in mitochondrial protein import [PDF]

, 1990
The process of insertion of precursor proteins into mitochondrial membranes was investigated using a hybrid protein (pSc1-c) that contains dual targeting information and, at the same time, membrane insertion activity.
Neupert, Walter, Nicholson, Donald W., Stuart, Rosemary A.   +2 more
core   +1 more source

U-insertion/deletion Edited Sequence Database [PDF]

Nucleic Acids Research, 1998
Uridine insertion/deletion RNA editing is a post-transcriptional RNA modification occurring in the mitochondria of kinetoplastid protozoa. The U-insertion/deletion Edited Sequence Database is a compilation of mitochondrial genes and edited mRNAs from five kinetoplastid species.
L, Simpson, S H, Wang, O H, Thiemann, J D, Alfonzo, D A, Maslov, H A, Avila   +5 more
openaire   +2 more sources

Insertion sequence-caused large-scale rearrangements in the genome of Escherichia coli

Nucleic Acids Research, 2016
A majority of large-scale bacterial genome rearrangements involve mobile genetic elements such as insertion sequence (IS) elements. Here we report novel insertions and excisions of IS elements and recombination between homologous IS elements identified ...
Heewook Lee, T. Doak, E. Popodi, P. Foster, Haixu Tang   +4 more
semanticscholar   +1 more source