Results 41 to 50 of about 595,744 (272)

Gamified interactive e-books for bullying prevention: enhancing knowledge and motivation in Chinese primary schools

Frontiers in Psychology
Bullying is increasingly prevalent in Chinese schools, contributing to a rise in associated criminal cases. A key factor in this trend is the lack of comprehensive understanding of bullying.
Jiawei Shao, Siti Nazleen Abdul Rabu, Chuang Chen   +2 more
doaj   +1 more source

Instructional Design of Call: a Perspective of Flexibility, Learning Goal, and Computer Roles [PDF]

, 2015
: Instructional Design of Call: A Perspective of Flexibility, Learning Goal, and Computer Roles. The purpose of this study is to review instructional design (ID) used in computer assisted language learning (CALL) studies.
Saukah, A. (Ali), Suarcaya, P. (Putu)
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Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Exploring Standards of Rigour for Design Cases [PDF]

, 2009
Designers share their specialized knowledge by developing design cases, which we define as representations of design efforts and outcomes disseminated to peers. In the field of instructional design this practice is not well established. In addition, many
Boling, Elizabeth, Smith, Kennon M
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Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Limits of Metacognitive Prompts for Confidence Judgments in an Interactive Learning Environment

Open Education Studies
Metacognitive activities are reported to improve learning but prompts to support metacognition have only been investigated with mixed results. In the present study, metacognitive prompts for confidence judgments were implemented in a learning platform to
Klar Maria, Buchner Josef, Kerres Michael   +2 more
doaj   +1 more source

Qualitative Content Analysis of Connectivism Theory and Introducing a Conceptual Model of Learning Ecology Design [PDF]

Interdisciplinary Journal of Virtual Learning in Medical Sciences, 2014
Introduction: The aim of this research was to qualitatively analyze the teaching and learning components of the connectivism theory and introduce a conceptual model for designing of the connectivist learning.Materials & Methods: The method of this study ...
Eisa Rezaei, Mohammadreza Nili, Hashem Fardanesh, Mohammad Shahalizadeh   +3 more
doaj  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

THE TEACHING OF ENGLISH TO YOUNG LEARNERS AT “PERMATA IMAN” KINDERGARTEN MALANG [PDF]

, 2007
Present trends show that the teaching of English is not only conducted in elementary schools but even in kindergarten. The society wants their children to learn English earlier and also the schools want to prepare their students before they face English ...
Ria Sari, Septi
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