Results 231 to 240 of about 635,202 (354)

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Endothelial insulin-like growth factor-1 signalling regulates vascular barrier function and atherogenesis. [PDF]

Cardiovasc Res
Drozd M, Bruns AF, Yuldasheva NY, Maqbool A, Viswambharan H, Skromna A, Makava N, Cheng CW, Sukumar P, Eades L, Walker AMN, Griffin KJ, Galloway S, Watt NT, Haywood N, Palin V, Warmke N, Imrie H, Bridge K, Beech DJ, Wheatcroft SB, Kearney MT, Cubbon RM.   +22 more
europepmc   +1 more source

Effects of Aerobic, Resistance, and Concurrent Training on Secretion of Growth Hormone and Insulin-Like Growth Factor-1 in Elderly Women

, 2012
Kh Jalali Dehkordi, Ali jalali dehkordi, Asghar Tofighi, Fazlolah Fatholahi Shourabeh, Mahnaz Sinaei   +4 more
openalex   +1 more source

Correlation between Insulin Like Growth Factor -1 and Anthropometric Measurements of Premature Infants

, 2016
Amina Abdelwahab, Abdelmoneim Khashana, Nesma Ahmed, Soha Younis   +3 more
openalex   +2 more sources

Variant in the 5′ Untranslated Region of Insulin-Like Growth Factor 1 Receptor Is Associated With Susceptibility to Mastitis in Cattle [PDF]

, 2012
Mayumi Sugimoto, Yoshikazu Sugimoto
openalex   +1 more source

Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways [PDF]

, 2016
Derek LeRoith, Haim Werner, Ilan Bruchim, Rive Sarfstein   +3 more
core   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Insulin-like Growth Factor 1 Impact on Alzheimer's Disease: Role in Inflammation, Stress, and Cognition. [PDF]

Curr Issues Mol Biol
Zegarra-Valdivia J, Arana-Nombera H, Perez-Fernandez L, Del Rocío Casimiro M, Gallegos-Manayay V, Del Rosario Oliva-Piscoya M, Alamo-Medina R, Abanto-Saldaña E, Cruz-Ordinola MC, Paredes-Manrique C, Chino-Vilca B.   +10 more
europepmc   +1 more source

A Cold Stress‐Activated Endocrine Sentinel Chemical Hormone Promotes Insect Survival via Mitochondrial Adaptations Through the Adipokinetic Hormone Receptor

Advanced Science, EarlyView.
Seasonal cold adaptation is vital for insect survival, yet the molecular mechanisms linking diapause to mitochondrial resilience remain largely unresolved. We identify ascaroside C9 (asc‐C9) as a key endocrine signal that enhances diapause survival during cold stress by activating the AKHR–PGC1α–UCP4 axis, thereby driving cold‐induced lipolysis and ...
Jiao Zhou, Junxian Chen, Hongxia Zhang, Lu Guo, Kevin Mai, Elijah Abraham, Dilip V. Prajapati, Yue Chang, Jing Ning, Xinchen Wang, Defeng Li, Dan‐Dan Zhang, Jianghua Sun, Rebecca A. Butcher, Lilin Zhao   +14 more
wiley   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

Advanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han, Chunsheng Wang, Xiuli Guo, Yuan Luo, Jianguo Zhang, Fajian He, Zihang Zeng, Jiang Luo, Wen Ouyang, Yan Gong, Conghua Xie   +10 more
wiley   +1 more source